EP0095946A1
Expired / Lapsed
EP
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Device for determining ionic activity
Assignee: Fujifilm Holdings Corp
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Filing: 1983-06-02
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Granted: —
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Expires: 2003-06-02
Abstract
Abstract A device for determining ionic activity is composed of plural pairs of ion-selective solid electrodes (26) each pair having two electrodes (one electrode on each of two sides) and each pair having a different type of ion-selective layer (26a, 26b, 26c); two liquid distribution porous members (32), each member being disposed overall the electrodes (26) or each said side of the plural pairs; and a porous capillary bridge (38) disposed on or between the liquid distribution porous members. The bridge (38) can be in liquid contact with all the electrodes (26) through the liquid distribution porous members (32) and achieve electrical conduction between two electrodes in each pair after spotting a test solution and a reference solution. The device preferably further comprises a support from (28) and a cover (35) having two apertures (36) for liquid spotting. The device can simultaneously determine ionic activities of a plurality of different ions in a test solution, such as whole blood, plasma, serum or urine, by spotting a test solution and a reference solution each in one operation and measuring the eletrical potential difference of each pair.
Inventors
- 👤 Masao Kitajima
- 👤 Osamu Seshimoto
- 👤 Kikuo Kubotera
- 👤 Akira Yamaguchi
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-01 12:35
CPC Classifications
G; G01; G01N; G01N27/00; G01N27/26; G01N27/28; G01N27/30; G01N27/307; G01N27/333; G01N27/3335
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
109 words
A device for determination of ionic activity in a liquid analyte, which comprises: at least two pairs of solid electrodes (26) each having as its outer layer an ion-selective layer (26a, b, c) responsive to a specified ion, at least two porous members (32) each in contact with at least part of the surface of the ion-selective layer of each pair of electrodes, the porous member being capable of supplying said liquid analyte and a reference solution to the electrodes, and a porous bridge (38) disposed over said porous members (32) to allow, during use of the device, electrical conduction between both electrodes in each pair through both solutions.
Claim 2
Independent Claim
109 words
A device for determination of ionic activity in a liquid analyte, which comprises: at least two pairs of solid electrodes (26) each having as its outer layer an ion-selective layer (26a, b, c) responsive to a specified ion, at least two porous members (32) each in contact with at least part of the surface of the ion-selective layer of each pair of electrodes, the porous member being capable of supplying said liquid analyte and a reference solution to the electrodes, and a porous bridge (38) disposed over said porous members (32) to allow, during use of the device, electrical conduction between both electrodes in each pair through both solutions.
Claim 3
Dependent Claim
19 words
A device as claimed in Claim 1, wherein said bridge (38) is composed of a twisted thread of fibres.
Claim 4
Dependent Claim
29 words
A device as claimed in Claim 1 or 2, which also includes a cell (34) for storage of the liquid and which has cavities for said porous members (32).
Claim 5
Dependent Claim
36 words
A device as claimed in Claim 3, wherein a separating element (30) between the cell (34) and electrodes (26) has apertures (31) for supply of liquid to defined parts of each electrode (26) in each pair.
Claim 6
Independent Claim
42 words
A device as claimed in any preceding claim, which also includes a cover (35) having two apertures (36) for supply to two porous members (32) of the analyte and reference solution respectively, and the porous bridge (38) bridges over said apertures (36).
Claim 7
Independent Claim
49 words
A device as claimed in any of Claims 1 to 4, which also includes a multilayer cover (35) having two apertures (36) for supply to two porous members (32) of the analyte and reference solution respectively, and the porous bridge (38) is retained between the layers of the cover.
Claim 8
Independent Claim
21 words
A device as claimed in any preceding claim, wherein the liquid distribution member (47) also acts as a liquid storage member.
Claim 9
Independent Claim
66 words
A device as claimed in any preceding claim, wherein each pair of solid electrodes (26) is a single electrode element comprising paired solid ion-selective electrodes comprising a common electrically insulating support having formed thereon a conductive metal layer which is divided into two electrically isolated portions by a groove, a layer of a water-insoluble salt. of said metal, and a common ion-selective layer (26a, b, c).
Claim 10
Independent Claim
64 words
A method of determining ionic activity in a liquid analyte, by means of a device as claimed in any preceding claim, which comprises applying the liquid analyte and a reference solution to the respective porous members (32), and applying a potential measuring device to a terminal (27) of each electrode, with the porous bridge (38) allowing electrical conduction between both electrodes in each pair.
Claim 11
Independent Claim
155 words
A device as claimed in any of Claims 1 to 9 for determining ionic activity, composed of plural pairs of solid electrodes (26) each pair having an ion-selective layer selectively responsive to a specific predetermined ion as the outermost layer of the solid electrodes and one porous bridge (38) formed thereon for achieving, after supplying a test solution and a reference solution to said pairs of solid electrodes (26), electrical conduction between both electrodes in each said pair by the permeation of the solutions through the bridge (38),and each electrode pair has one electrode on each of two sides and has a different ion-selective layer, at least one liquid distribution porous member (32) being provided for each said side of plural pairs of solid electrodes so that said porous member (32) covers at least partially all the electrodes at each said side, and said bridge (38) is disposed on or between said liquid distribution members.
References Cited (Backward Citations)
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