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EP0094924A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Articles exhibiting a biocompatible surface layer and process for providing articles with such a surface layer

Assignee: Astra Meditec AB
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Filing: 1983-05-13
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Granted: —
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Expires: 2003-05-13
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Abstract

Abstract A process for providing a surface of glass, silicon, aluminium or silicone rubber of an article useful within medicine with a biocompatible surface layer. Said surface is reacted (after oxidation when required) with a silane containing at least one epoxy group and the surface thus treated is then reacted with a polysaccharide containing at least one hydroxyl group. The invention also relates to an article exhibiting a biocompatible surface layer of a polysaccharide containing at least one hydroxyl group, which polysaccharide is covalently bound to a surface of glass, silicon, aluminium or silicone rubber of the article by means of a silane.

Inventors

  • 👤 Bo Hakan Nygren
  • 👤 Johan Emanuel Stenberg

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-04 16:16
CPC Classifications
A; A61; A61L; A61L33/00; A61L33/0005; A61L33/0011; A61L33/0029; A61L33/06; A61L33/08; C; C08; C08K; C08K3/00; C08K3/02; C08K3/08; C08K3/40; C08K5/00; C08K5/54; C08L; C08L83/00; C08L83/04; Y; Y10; Y10T; Y10T428/00; Y10T428/13; Y10T428/131; Y10T428/1317; Y10T428/1321; Y10T428/1352; Y10T428/1355; Y10T428/1386; Y10T428/139; Y10T428/1393; Y10T428/31504; Y10T428/31511; Y10T428/31515; Y10T428/31518; Y10T428/31522; Y10T428/31551; Y10T428/31609; Y10T428/31612; Y10T428/31652; Y10T428/31663; Y10T428/31971

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 59 words
Article exhibiting at least one surface of glass, silicon, aluminium or silicone rubber coated with a biocompatible surface layer, characterized in that the biocompatible surface layer consists of a polysaccharide containing at least one hydroxyl group, which polysaccharide is covalently bound to said surface of glass, silicon, aluminium or silicone rubber of the article by means of a silane.
Claim 2
Dependent Claim 59 words
Article exhibiting at least one surface of glass, silicon, aluminium or silicone rubber coated with a biocompatible surface layer, characterized in that the biocompatible surface layer consists of a polysaccharide containing at least one hydroxyl group, which polysaccharide is covalently bound to said surface of glass, silicon, aluminium or silicone rubber of the article by means of a silane.
Claim 3
Dependent Claim 21 words
Article according to claim 1, characterized in that it is a catheter or a device for sampling and/or storage of blood.
Claim 4
Dependent Claim 33 words
Article according to claim 1, characterized in that it is a heart-lung machine, in which machine aluminium surfaces of the machine coming into contact with blood are coated with the biocompatible surface layer.
Claim 5
Dependent Claim 62 words
Process for providing articles exhibiting . at least one surface of glass, silicon, aluminium or silicone rubber with a biocompatible surface layer, characterized in that said surface of.the article, after oxidation thereof when required, is reacted with a silane containing at least one epoxy group and that the surface thus treated is reacted with a polysaccharide containing at least one hydroxyl group.
Claim 6
Dependent Claim 62 words
Process for providing articles exhibiting . at least one surface of glass, silicon, aluminium or silicone rubber with a biocompatible surface layer, characterized in that said surface of.the article, after oxidation thereof when required, is reacted with a silane containing at least one epoxy group and that the surface thus treated is reacted with a polysaccharide containing at least one hydroxyl group.
Claim 7
Dependent Claim 17 words
A process according to claim 4, characterized in that a neutral polysaccharide is used as said saccharide.
Claim 8
Dependent Claim 16 words
A process according to claim 5, characterized in that dextran is used as said neutral polysaccharide.

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