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A stable radioactive diagnostic agent and a non-radioactive carrier therefor

Assignee: Nihon Medi Physics Co Ltd
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Filing: 1982-12-01
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Granted: —
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Expires: 2002-12-01
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Abstract

Abstract A stable non-radioactive carrier for use in production of To labeled radioactive diagnostic agent comprising a chelating agent, a water-soluble reducing agent for pertechnetate and a stabilizer chosen from ascorbic acid and erythorbic acid, and their pharmaceutically acceptable salts and esters In an amount of more than about 100 moles per 1 mol of said water-soluble reducing agent.

Inventors

  • 👤 Makoto Azuma
  • 👤 Masaaki Hazue

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-09 09:34
CPC Classifications
A; A61; A61B; A61B6/00; A61K; A61K51/00; A61K51/02; A61K51/04; A61K51/0474; A61K51/0478; A61K2123/00

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 58 words
A stable non-radioactive carrier for use in production of 99m Tc-labeled radioactive diagnostic agent comprising a chelating agent, a water-soluble reducing agent for pertechnetate and a stabilizer chosen from ascorbic acid and erythorbic acid, and their pharmaceutically acceptable salts and esters in an amount of more than about 100 moles per 1 mol of said water-soluble reducing agent.
Claim 2
Dependent Claim 58 words
A stable non-radioactive carrier for use in production of 99m Tc-labeled radioactive diagnostic agent comprising a chelating agent, a water-soluble reducing agent for pertechnetate and a stabilizer chosen from ascorbic acid and erythorbic acid, and their pharmaceutically acceptable salts and esters in an amount of more than about 100 moles per 1 mol of said water-soluble reducing agent.
Claim 3
Dependent Claim 17 words
The stable non-radioactive carrier according to claim l, wherein the water-soluble reducing agent is a stannous salt.
Claim 4
Dependent Claim 64 words
3 . A stable 99m Tc-labeled radioactive diagnostic agent which is produced by contacting 99m Tc-containing pertechnetate with a non-radioactive carrier comprising a chelating agent, an water-soluble reducing agent for pertechnetate and a stabilizer chosen from ascorbic acid and arythorbic acid, and pharmaceutically acceptable salts and esters in an amount of more than about 100 moles per 1 mol of said water-soluble reducing agent.
Claim 5
Dependent Claim 64 words
3 . A stable 99m Tc-labeled radioactive diagnostic agent which is produced by contacting 99m Tc-containing pertechnetate with a non-radioactive carrier comprising a chelating agent, an water-soluble reducing agent for pertechnetate and a stabilizer chosen from ascorbic acid and arythorbic acid, and pharmaceutically acceptable salts and esters in an amount of more than about 100 moles per 1 mol of said water-soluble reducing agent.
Claim 6
Dependent Claim 20 words
The stable 99m Tc-labeled radioactive diagnostic agent according to claim 3, wherein the water-soluble reducing agent is a stannous salt.

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