EP0078434A1
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Pharmaceutical and dietary compositions
Assignee: Efamol Ltd
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Filing: 1981-03-03
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Granted: —
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Expires: 2001-03-03
Abstract
Abstract A pharmaceutical composition comprises y-linolenic acid and/or dihomo-y-linolenic acid together with a compound influencing the 1-series/2-series PG balance in the body in favour of 1-series PGs and selected from spironolactone and other modified steroid having its action, alone or in an acceptable pharmaceutical vehicle.
Inventors
- 👤 David Frederick Horrobin
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-05 16:11
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/56; A61K31/58; A61K31/21; A61K31/215; A61K31/235; A61K31/24; A61K31/245; A61K31/33; A61K31/335; A61K31/365; A61K31/375; A61K31/395; A61K31/41; A61K31/425; A61K31/429; A61K31/43; A61K31/435; A61K31/47; A61K31/475; A61K31/485; A61K31/49; A61K31/585; A61K33/00; A61K33/24; A61K33/30; A61K38/00; A61K38/16; A61K38/17; A61K38/19; A61K38/21; A61K45/00; A61K45/06; A61P; A61P43/00
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
54 words
A pharmaceutical composition comprising y-linolenic acid or physiologically functional derivative thereof and/or dihomo-y-linolenic acid or physiologically functional derivative thereof together with a compound influencing the l-series/2-series PG balance in the body in favour of 1-series PGs and selected from spironolactone and other modified steroid having its action alone or in an acceptable pharmaceutical vehicle.
Claim 2
Dependent Claim
54 words
A pharmaceutical composition comprising y-linolenic acid or physiologically functional derivative thereof and/or dihomo-y-linolenic acid or physiologically functional derivative thereof together with a compound influencing the l-series/2-series PG balance in the body in favour of 1-series PGs and selected from spironolactone and other modified steroid having its action alone or in an acceptable pharmaceutical vehicle.
Claim 3
Dependent Claim
23 words
A composition according to claim 1, presented for administration in quantities to give doses of 30 mg to 2 g/day of said steroid.
Claim 4
Dependent Claim
28 words
A composition according to claim 1, presented for administration in quantities to give 0.05 to 10 g/day of said y-linolenic or dihomo-γ-linolenic acid or derivative,calculated as y-linolenic acid.
Claim 5
Dependent Claim
18 words
A composition according to claim 1, further comprising physiologically assimible zinc, a 6-lactam antibiotic, penicillamine, phenformin or levamisole.
Claim 6
Dependent Claim
43 words
A composition according to claim 4, presented for administration in quantities to give 2.5 to 800 mg/day zinc, 0.5 to 10 g/day 6-lactam antibiotic, 50 mg to 10 g/day penicillamine, 10 mg to 5 g/day phenformin or 10 mg to 2 g/day levamisole.
Claim 7
Dependent Claim
24 words
A composition according to claim 1 further comprising a material selected from colchicine, griseofulvin, amantadine, melatonin, interferon, and vinblastine, vincristine and other Vinca alkaloids.
Claim 8
Dependent Claim
59 words
A composition according to claim 6, presented for administration in quantities to give doses of: 0.3 to 15 mg/day colchicine 100 to 1000 mg/day amantadine 0.5 to 5 g/day griseofulvin 35 to 350 mg/week vinblastine 7 to 70 mg/week vincristine 1 x 1 0 5 to 1 x 10 8 units/day interferon, or 10 mg to 5 g/day melatonin.
Claim 9
Dependent Claim
24 words
A composition according to claim 1, further comprising a material selected from Vitamin C, ethyl alcohol, and naloxone, nalorphine, levallorphan or other opiate antagonist.
Claim 10
Dependent Claim
55 words
A composition according to claim 8, presented for administration in quantities to give doses of: 50 mg to 50 g/day ascorbic acid or 5 to 500 ml/day ethyl alcohol or 0.1 to 500 mg/day naloxone, 1 mg to 5 g/day nalorphine, 0 .2 mg to 1 g/day levallorphan or comparable amount of other opiate antagonist
Claim 11
Dependent Claim
18 words
A composition according to any preceding claim, for use in treatment of any of the diseases specified herein.
Claim 12
Dependent Claim
26 words
A pharmaceutical pack comprising the materials set out in any preceding claim presented separately, or one or more separately and others together, but for conjoint administration.
References Cited (Backward Citations)
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