Patent US2483655A successfully refreshed from Google Patents.
Patent EP0055313A1 successfully refreshed from Google Patents.
EP0055313A1
Expired / Lapsed
EP
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Guaiacol and derivatives; compositions thereof and use in a method of treatment
Assignee: Ed Geistlich Soehne AG fuer Chemische Industrie
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Filing: 1980-12-30
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Granted: —
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Expires: 2000-12-30
Abstract
Abstract The invention relates to a pharmaceutical composition for the treatment of heartburn by oral administration or the treatment of constipation of the large bowel by rectal administration which composition comprises guaiacol or a pharmaceutically acceptable derivative thereof and (a) at least one alkaline compound suitable for neutralising gastric acids and/or a mucilage compatible with the alimentary tract and/or a silicone antifoam or (b) a suppository mass. Guaiacol and its derivatives, formulated into pharmaceutical compositions have surprisingly been found to be useful in the treatment of heartburn or constipation.
Inventors
- 👤 John Rhodes
- 👤 Brian Kenneth Evans
- 👤 Richard Val Heatley
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-05 23:05
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0087; A61K9/0095; A61K31/00; A61K31/075; A61K31/085; A61K31/09; A61K33/00; A61K33/06; A61K33/08; A61K47/00; A61K47/30; A61K47/36; A61K9/20; A61K9/2004; A61K9/2013; A61K9/2018
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
62 words
A pharmaceutical composition for the treatment of heartburn by oral administration or the treatment of constipation of the large bowel by rectal administration which composition comprises guaiacol or a pharmaceutically acceptable derivative thereof and (a) at least one alkaline compound suitable for neutralising gastric acids and/or a mucilage compatible with the alimentary tract and/or a silicone antifoam or (b) a suppository mass.
Claim 2
Dependent Claim
62 words
A pharmaceutical composition for the treatment of heartburn by oral administration or the treatment of constipation of the large bowel by rectal administration which composition comprises guaiacol or a pharmaceutically acceptable derivative thereof and (a) at least one alkaline compound suitable for neutralising gastric acids and/or a mucilage compatible with the alimentary tract and/or a silicone antifoam or (b) a suppository mass.
Claim 3
Dependent Claim
14 words
A composition as claimed in claim 1 wherein the said guaiacol derivative is guaiaphenesin.
Claim 4
Dependent Claim
31 words
A composition as claimed in either of claims 1 and 2 wherein the said alkaline compounds are a 5:7 to 1.1 ratio by weight mixture of alkaline magnesium and aluminium compounds.
Claim 5
Dependent Claim
44 words
A composition as claimed in any one of claims 1 to 3 wherein the said mucilage is an aqueous solution of at least one of the following : alginic acid, alginates, gum tragacanth, gum arabic, methyl cellulose, karaya or sterculia gum, and sodium carboxymethylcellulose.
Claim 6
Dependent Claim
32 words
A composition as claimed in any one of claims 1 to 4 in dosage unit form comprising from 10 to 1000 mg per dose of guaiacol or a pharmaceutically acceptable derivative thereof.
Claim 7
Dependent Claim
29 words
A composition as claimed in any one of claims 1 to 5 in dosage unit form comprising from 0.2 to 1.6 g per dose of the said alkaline compound.
Claim 8
Dependent Claim
35 words
A composition as claimed in any one of claims 1 to-6 in dosage unit form comprising from 0.5 to 1.0 g per dose of alginic acid and sodium alginate as the base for the mucilage.
Claim 9
Dependent Claim
20 words
A mixture comprising the non-aqueous components of a pharmaceutical composition as claimed in any one of claims 1 to 7.
Claim 10
Dependent Claim
21 words
G uaiacol and .its pharmaceutically acceptable derivatives for use in the treatment of heartburn or of constipation of the large bowel.
Claim 11
Dependent Claim
21 words
G uaiacol and .its pharmaceutically acceptable derivatives for use in the treatment of heartburn or of constipation of the large bowel.
References Cited (Backward Citations)
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