Patent EP0049422A2 successfully refreshed from Google Patents.
EP0049422A2
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Stable nonaqueous solution of tetracycline salt
Assignee: Bayer Corp
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Filing: 1981-09-23
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Granted: —
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Expires: 2001-09-23
Abstract
Abstract Nonaqueous solution of a tetracycline antibiotic salt which is stable upon extended storage comprises a mixture of a tetracycline antibiotic salt, nonaqueous diluent, nonaqueous solvent, and nonaqueous nonionic solubilizer. It preferably also contains an anti-oxidant and a nonaqueous anionic solubilizer.
Inventors
- 👤 Lawrence John Daher
- 👤 George Carr Hoss
- 👤 Victor Albert Raul
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-02 16:39
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/65
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
25 words
A stable nonaqueous solution of a tetracycline antibiotic salt comprising a mixture of a tetracycline antibiotic salt, nonaqueous diluent, nonaqueous solvent and nonaqueous nonionic solubilizer.
Claim 2
Dependent Claim
25 words
A stable nonaqueous solution of a tetracycline antibiotic salt comprising a mixture of a tetracycline antibiotic salt, nonaqueous diluent, nonaqueous solvent and nonaqueous nonionic solubilizer.
Claim 3
Dependent Claim
12 words
A stable solution of Claim 1 also containing a nonaqueous anionic solubilizer.
Claim 4
Dependent Claim
10 words
A stable solution of Claim 1 also containing an antioxidant.
Claim 5
Dependent Claim
65 words
A stable nonaqueous solution of a tetracycline antibiotic salt comprising a mixture of 0.25 to 2 percent tetracycline antibiotic salt, 41 to 88 percent nonaqueous diluent, 4 to 40.percent nonaqueous solvent, 0.3 to 20 percent nonaqueous nonionic solubilizer, 0 to 6 percent nonaqueous anionic solubilizer and 0 to 0.75 percent antioxidant, said percent values being on a weight/weight basis based on the entire solution weight.
Claim 6
Dependent Claim
65 words
A stable nonaqueous solution of a tetracycline antibiotic salt comprising a mixture of 0.25 to 2 percent tetracycline antibiotic salt, 41 to 88 percent nonaqueous diluent, 4 to 40.percent nonaqueous solvent, 0.3 to 20 percent nonaqueous nonionic solubilizer, 0 to 6 percent nonaqueous anionic solubilizer and 0 to 0.75 percent antioxidant, said percent values being on a weight/weight basis based on the entire solution weight.
Claim 7
Dependent Claim
55 words
A stable solution according to Claim 4 wherein the components are present in the amounts of 0.3 to 1.5 percent tetracycline antibiotic salt, 57 to 84 percent nonaqueous diluent, 4 to 30 percent nonaqueous solvent, 2 to 9 percent nonaqueous nonionic solubilizer, 1 to 6 percent nonaqueous anionic solubilizer and 0.03 to 0.2 percent antioxidant.
Claim 8
Dependent Claim
56 words
A stable solution according to Claim 4 wherein the components are present in the amounts of 0.5 to 1.25 percent tetracycline antibiotic salt, 60 to 81 percent nonaqueous diluent, 4 to 25 percent nonaqueous solvent, 3 to 9 percent nonaqueous nonionic solubilizer, 1.5 to 4.5 percent nonaqueous anionic solu- bilzier and 0.1 to 0.2 percent antioxidant.
References Cited (Backward Citations)
No citation records indexed.
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