Patent EP0041772A2 successfully refreshed from Google Patents.
EP0041772A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Fat emulsion containing a steroid
Assignee: Tanabe Pharma Corp
•
Filing: 1981-05-01
•
Granted: —
•
Expires: 2001-05-01
Abstract
Abstract A steroid having an anti-inflammatory activity can be administered as a fat emulsion thereof. The emulsion may comprise an effective quantity of the steroid having an anti-inflammatory activity, 5 to 50% (W/V) of soybean oil, a phospholipid in a weight ratio of 1-50 to 100 of said soybean oil, and a proper quantity of water. This fat emulsion exhibits a long-lasting activity in the region of inflammation and is especially useful in the therapeutic or prophylactic treatment of rheumatism, immunological hemolytic anemia, idopathic thrombocytopenic purpura, and Paget's disease, or in conjunction with kidney transplantation.
Inventors
- 👤 Yutaka Mizushima
- 👤 Kasumasa Yokoyama
- 👤 Kiichiro Nabeta
- 👤 Noboru Yamada
- 👤 Tadakazu Suyama
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-24 05:45
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/10; A61K9/107; A61K9/1075; A61K31/00; A61K31/56; A61K31/57; A61P; A61P29/00
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
10 words
A fat emulsion containing a steroid having an anti-inflammatory activity.
Claim 2
Dependent Claim
10 words
A fat emulsion containing a steroid having an anti-inflammatory activity.
Claim 3
Dependent Claim
47 words
A fat emulsion according to Claim 1, comprising an effective quantity of a steroid having an anti-inflammatory activity, 5 to 50% (W/V) of soybean oil, a phospholipid in a weight ratio of 1 - 50 to 100 of said soybean oil, and a proper quantity of water.
Claim 4
Dependent Claim
22 words
A fat emulsion according to Claim 2, wherein the steroid having an anti-inflammatory activity is a steroid having a highly lipophilic group.
Claim 5
Dependent Claim
37 words
4 . A fat emulsion according to Claim 3, wherein the steroid having a highly lipophilic group is dexamethasone palmitate, dexamethasone stearate, dexamethasone myristate, hydrocortisone palmitate, hydrocortisone stearate, hydrocortisone myristate, prednisolone palmitate, prednisolone stearate, or prednisolone myristate.
Claim 6
Dependent Claim
12 words
A fat emulsion according to Claim 2, which contains an isotonizing agent.
Claim 7
Dependent Claim
40 words
A fat emulsion accordihg to Claim 2, wherein the fat emulsion contains, as an auxiliary emulsifier or an emulsion stabilizer, up to 0.3% (W/V) of a fatty acid having 6 to 22 carbon atoms or a physiologically acceptable salt thereof.
Claim 8
Dependent Claim
29 words
A fat emulsion according to Claim 2, wherein the fat emulsion contains as a stabilizer 0.5% (W/V) or less of cholesterol or 5% (W/V) or less of phosphatidic acid.
Claim 9
Dependent Claim
36 words
A fat emulsion according to Claim 2, wherein the fat emulsion contains as a stabilizer at least one member selected from the group consisting of albumin, dextran, vinyl polymers, nonionic surface active agents, gelatin, and hydroxyethylstarch.
Claim 10
Dependent Claim
25 words
A process for preparing a pharmaceutical preparation containing a steroid having an anti-inflammatory activity which comprises forming an emulsion of the steroid with a fat.
Claim 11
Dependent Claim
25 words
A process for preparing a pharmaceutical preparation containing a steroid having an anti-inflammatory activity which comprises forming an emulsion of the steroid with a fat.
Claim 12
Dependent Claim
50 words
A process according to claim 1, wherein the fat emulsion contains an effective quantity of the steroid having an anti-inflammatory activity, 5 to 50% (W/V) of soybean oil, a phospholipid in a weight ratio of 1 - 50 to 100 of said soybean oil, and a proper quantity of water.
Claim 13
Dependent Claim
21 words
A process according to claim 2, wherein the steroid having an anti-inflammatory activity is a steroid having a highly lipophilic group.
Claim 14
Dependent Claim
34 words
A process according to claim 3, wherein the steroid having a highly lipophilic group is dexamethasone palmitate, dexamethasone stearate, dexamethasone myristate, hydrocortisone palmitate, hydrocortisone stearate, hydrocortisone myristate, prednisolone palmitate, prednisolone stearate, or prednisolone myristate.
Claim 15
Dependent Claim
11 words
A process according to claim 2, which contains an isotonizing agent.
Claim 16
Dependent Claim
39 words
A process according to claim 2, wherein the fat emulsion contains, as an auxiliary emulsifier or an emulsion stabilizer, up to 0.3% (W/V) of a fatty acid having 6 to 22 carbon atoms or a physiologically acceptable salt thereof.
Claim 17
Dependent Claim
28 words
A process according to claim 2, wherein the fat emulsion contains as a stabilizer 0.5% (W/V) or less of cholesterol or 5% (W/V) or less of phosphatidic acid.
Claim 18
Dependent Claim
35 words
A process according to claim 2, wherein the fat emulsion contains as a stabilizer at least one member selected from the group consisting of albumin, dextran, vinyl polymers, nonionic surface active agents, gelatin, and hydroxyethylstarch.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.