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EP0041175A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Ion specific analytical element

Assignee: Bayer Corp
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Filing: 1981-05-25
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Granted: —
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Expires: 2001-05-25
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Abstract

Abstract A method for the determination of an ion in a liquid sample and an analytical element for use in such determinations are disclosed. More particularly, the contemplated method comprises contacting an analytical element with the sample in the presence of a detectable species associated with an ionic analyte, said analytical element comprising a layer of substantially nonpolar material incorporated with an analyte-specific ionphore, and measuring the amount of said detectable species which has migrated to at least a surface portion of said analytical element, the amount of said detectable species which has migrated being indicative of the concentration of the specific ionic analyte in the sample. The analytical element can include a layer of substantially nonpolar material incorporated with an analyte-specific ionophore and, in laminar relationship therewith, a second layer incorporated with a detectable species associated with said ionic analyte.

Inventors

  • 👤 Steven C. Charlton

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-29 18:13
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/84; G01N33/52; G01N33/525; G01N33/526

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 97 words
A method for determining the concentration of a specific ionic analyte in a liquid sample, which method comprises contacting an integral analytical element with the sample in the presence of a detectable species associated with said ionic analyte, said analytical element comprising a layer of substantially nonpolar material incorporated with an analyte-specific ionophore; and photometrically measuring the amount of said detectable species which has migrated to at least a surface portion of said analytical element, the amount of said detectable species which has migrated being indicative of the concentration of the specific ionic analyte in the sample.
Claim 2
Independent Claim 97 words
A method for determining the concentration of a specific ionic analyte in a liquid sample, which method comprises contacting an integral analytical element with the sample in the presence of a detectable species associated with said ionic analyte, said analytical element comprising a layer of substantially nonpolar material incorporated with an analyte-specific ionophore; and photometrically measuring the amount of said detectable species which has migrated to at least a surface portion of said analytical element, the amount of said detectable species which has migrated being indicative of the concentration of the specific ionic analyte in the sample.
Claim 3
Dependent Claim 36 words
The method of claim 1 wherein said contacting comprises adding to said liquid sample a detectable species which is associated with said ionic analyte and then contacting said analytical element with the detectable species containing sample.
Claim 4
Dependent Claim 49 words
The method of claim 1 wherein said contacting comprises contacting an analytical element with the sample, said analytical element comprising a layer of substantially nonpolar material incorporated with an analyte-specific ionophore; and, in laminar relationship therewith, a second layer incorporated with a detectable species associated with said ionic analyte.
Claim 5
Independent Claim 30 words
The method of claims 1 to 3 wherein after said contacting and before said measuring said method comprises the additional step of removing any excess sample from said analytical element.
Claim 6
Dependent Claim 40 words
The method of claim 3 wherein said ionophore layer has a pair of opposite surfaces, said detectable species layer being in laminar relationship with one of said pair of surfaces and said contacting comprises contacting the other of said surfaces.
Claim 7
Dependent Claim 40 words
The method of claim 3 wherein said detectable species layer has a pair of opposite surfaces, said ionophore layer being in laminar relationship with one of said pair of surfaces and said contacting comprises contacting the other of said surfaces.
Claim 8
Dependent Claim 50 words
An integral analytical element for determining the concentration of a specific ionic analyte in a liquid sample, which analytical element comprises a layer of substantially nonpolar material incorporated with an analyte-specific ionophore; and, in laminar relationship therewith, a second layer incorporated with a detectable species associated with said ionic analyte.
Claim 9
Dependent Claim 50 words
An integral analytical element for determining the concentration of a specific ionic analyte in a liquid sample, which analytical element comprises a layer of substantially nonpolar material incorporated with an analyte-specific ionophore; and, in laminar relationship therewith, a second layer incorporated with a detectable species associated with said ionic analyte.
Claim 10
Dependent Claim 43 words
8 . The analytical element of claim 7 wherein said ionophore layer has a pair of opposite surfaces, said detectable species layer being in laminar relationship with one of said pair of surfaces and said contacting comprises contacting the other of said surfaces.
Claim 11
Dependent Claim 41 words
The analytical element of claim 7 wherein said detectable species layer has a pair of opposite surfaces, said ionophore layer being in laminar relationship with one of said pair of surfaces and said contacting comprises contacting the other of said surfaces.
Claim 12
Dependent Claim 34 words
10 . The analytical element of any of claims 7-9 wherein the substantially nonpolar material of said ionophore layer is a composition comprising a plasticizer and a nonpolar polymer suitable to impart dimensional stability.

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