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EP0038567A1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Deazapurine nucleoside, formulations thereof, and use thereof in therapy

Assignee: Wellcome Foundation Ltd
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Filing: 1981-04-22
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Granted: —
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Expires: 2001-04-22
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Abstract

Abstract The use of 3-deazaadenosine, 4-amino-1-β-D-ribofuranosyl-1H-imidazo-[4,5-c] pyridine, for the treatment of inflammation in mammals, including man, is disclosed. Pharmaceutical formulations suitable for administration of the compound, in particular topical formulations for local application, are also disclosed.

Inventors

  • 👤 Ralph Vinegar
  • 👤 Gerald Wolberg

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-08 15:37
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/052; A; A61; A61P; A61P29/00

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 28 words
A pharmaceutical formulation adapted for topical application and comprising, as active ingredient, 4-amino-1-β-D-ribofuranosyl-1H-imidazo-[4,5-c]-pyridine or a pharmaceutically acceptable acid addition salt thereof together with a pharmaceutically acceptable carrier therefor.
Claim 2
Dependent Claim 28 words
A pharmaceutical formulation adapted for topical application and comprising, as active ingredient, 4-amino-1-β-D-ribofuranosyl-1H-imidazo-[4,5-c]-pyridine or a pharmaceutically acceptable acid addition salt thereof together with a pharmaceutically acceptable carrier therefor.
Claim 3
Dependent Claim 20 words
A formulation as claimed in claim 1 in the form of a lotion, jelly, spray, aerosol, bain oil or ointment.
Claim 4
Dependent Claim 16 words
A formulation as claimed in claim 1 or claim 2 in the form of an ointment.
Claim 5
Dependent Claim 19 words
A formulation as claimed in claim 3 in which the ointment has an oleaginous, absorption, water-soluble or emulsion-type base.
Claim 6
Dependent Claim 24 words
A formulation as claimed in either of claims 3 or claim 4 in which the base comprises petrolatum, lanolin, polyethylene glycols and mixtures thereof.
Claim 7
Dependent Claim 17 words
A formulation as claimed in any of claims 3 to 5 in the form of a cream.
Claim 8
Dependent Claim 30 words
A formulation as claimed in any one of claims 1 to 4 in which the concentration of the active ingredient is in the range of from 0.1% to 10% w/w.
Claim 9
Dependent Claim 20 words
A formulation as claimed in claim 5 in which the concentration of active ingredient is from 0.2 to 0.5% w/w.
Claim 10
Dependent Claim 16 words
4-Amino-1-β-D-ribofuranosyl-1H-imidazo-[4,5-c]-pyridine or a pharmaceutically acceptable acid addition salt thereof for use in the treatment of inflammation.
Claim 11
Dependent Claim 16 words
4-Amino-1-β-D-ribofuranosyl-1H-imidazo-[4,5-c]-pyridine or a pharmaceutically acceptable acid addition salt thereof for use in the treatment of inflammation.

References Cited (Backward Citations)

US4148888A Cited
EP0010668A1 Cited

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