EP0025699A1
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Device for drug delivery to ruminants
Assignee: Eli Lilly and Co
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Filing: 1980-09-11
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Granted: —
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Expires: 2000-09-11
Abstract
Abstract Drug-delivery device for controlably releasing a drug to a ruminant is comprised of a coated steel cylinder (2) open at both ends, of sufficient specific gravity to be retained in the reticulo-rumen portion of the ruminant stomach, and having a retaining means (3) therein to prevent premature expulsion of a formulated drug core.
Inventors
- 👤 Barbara Ellen Simpson
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-04 23:43
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0068; A61D; A61D7/00; A61M; A61M31/00; A61M31/002
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
103 words
A drug delivery device for oral delivery to the reticulo-rumen of a ruminant a controlled release formulation, said device comprising a steel cylinder open at both ends, said cylinder having an inside diameter to length ratio of about 0.55 to about 0.75, having a density from about 2.0 to about 3.5 g/cc, retaining means being provided on or in engagement with the inner, wall of the cylinder said device being coated with a substance which does not promote depolymerization of a copolymer derived from about 60 to about 95 weight percent lactic acid and about 40 to about 5 weight percent glycolic acid.
Claim 2
Dependent Claim
103 words
A drug delivery device for oral delivery to the reticulo-rumen of a ruminant a controlled release formulation, said device comprising a steel cylinder open at both ends, said cylinder having an inside diameter to length ratio of about 0.55 to about 0.75, having a density from about 2.0 to about 3.5 g/cc, retaining means being provided on or in engagement with the inner, wall of the cylinder said device being coated with a substance which does not promote depolymerization of a copolymer derived from about 60 to about 95 weight percent lactic acid and about 40 to about 5 weight percent glycolic acid.
Claim 3
Dependent Claim
37 words
The device of claim 1 wherein the retaining means is a multiplicity of grooves cut in the innersurface of the walls, said grooves having a depth of about 20 to about 50 percent of the wall thickness.
Claim 4
Dependent Claim
26 words
The device of claim 2 wherein said inner grooves are about 0.2 to about 2.0 millimeters in width and about 1 to about 5 millimeters apart.
Claim 5
Dependent Claim
26 words
The device of claim 3 wherein said inner grooves are about 0.6 to about 1.0 millimeters in width and about 2 to about 3 millimeters apart.
Claim 6
Dependent Claim
28 words
The device of claim 4, said device having an inside diameter of about 11 to about 35 millimeters and a length of about 20 to about 64 millimeters.
Claim 7
Dependent Claim
19 words
The device of claim 5, said device measuring about 30 millimeters in diameter and about 50 millimeters in length.
Claim 8
Dependent Claim
19 words
The device of claim 5, said device measuring about 15 millimeters in diameter and about 25 millimeters in length.
Claim 9
Dependent Claim
14 words
The device of claim 1 wherein said coating comprises nickel, magnesium, silver or aluminum.
Claim 10
Dependent Claim
10 words
The device of claim 8 wherein said coating comprises nickel.
Claim 11
Dependent Claim
13 words
The device of claim 1 wherein said coating comprises a food grade enamel.
Claim 12
Dependent Claim
12 words
ll. The device of claim 10 wherein said coating comprises epoxyphenolic resins.
Claim 13
Dependent Claim
12 words
The device of claim 1 wherein said density is about 2.9 g/cc.
Claim 14
Dependent Claim
25 words
A drug delivery device according to any preceding claim, charged with a sustained-release formulation of an active ingredient exhibiting a desired effect on ruminant animals.
References Cited (Backward Citations)
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FR2287242A1
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DE2824288A1
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US4228149A
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