Patent EP0011528B1 successfully refreshed from Google Patents.
EP0011528B1
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EP
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Osteosynthesis elements and their preparation
Assignee: Centre National de la Recherche Scientifique
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Filing: 1979-10-19
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Granted: 1985-02-20
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Expires: 1999-10-19
Abstract
No abstract record available.
Inventors
- 👤 Michel Vert
- 👤 François Chabot
- 👤 Jean Leray
- 👤 Pascal Christel
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 11:59
CPC Classifications
A; A61; A61L; A61L31/00; A61L31/04; A61L31/06; A61B; A61B17/00; A61B17/56; A61B17/58; A61B17/68; A61L27/00; A61L27/40; A61L27/44; A61L27/48; A61L31/12; A61L31/125; A61L31/129; A61B2017/00004; A61L2430/00; A61L2430/02
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
140 words
Compositions for use in bone surgery as composite osteosynthesis pieces, having the shape of a three-dimensional solid, the compositions being based on a biocompatible absorbable polymer, characterised in that they consist of a matrix of poly(lactic acid) or of a copolymer thereof, the said copolymer comprising, in terms of number of units, at least 90% of the units derived from lactic acid, and the said matrix containing enforcing elements embedded in the matrix and consisting of a homopolymer or copolymer of polyglycolic acid, the said reinforcing elements having the shape of filaments, films, fabrics, braids or mats and being present in an amount of 5 to 50% by weight relative to the total weight of the composition, and in that they optionally contain a filler capable of stimulating the absorption of the polymer to the benefit of newly formed tissue.
Claim 2
Dependent Claim
140 words
Compositions for use in bone surgery as composite osteosynthesis pieces, having the shape of a three-dimensional solid, the compositions being based on a biocompatible absorbable polymer, characterised in that they consist of a matrix of poly(lactic acid) or of a copolymer thereof, the said copolymer comprising, in terms of number of units, at least 90% of the units derived from lactic acid, and the said matrix containing enforcing elements embedded in the matrix and consisting of a homopolymer or copolymer of polyglycolic acid, the said reinforcing elements having the shape of filaments, films, fabrics, braids or mats and being present in an amount of 5 to 50% by weight relative to the total weight of the composition, and in that they optionally contain a filler capable of stimulating the absorption of the polymer to the benefit of newly formed tissue.
Claim 3
Dependent Claim
26 words
Compositions according to Claim 1, characterised in that the matrix consists of a polymer of D-lactic acid or of L-lactic acid, of high enan- tiometric purity.
Claim 4
Dependent Claim
22 words
Compositions according to Claim 1, characterised in that the matrix consists of a bio-absorbable copolymer of lactic acid and a compatible comonomer.
Claim 5
Dependent Claim
20 words
Compositions according to Claim 3, characterised in that the said copolymer contains 95 % of units derived from lactic acid.
Claim 6
Dependent Claim
43 words
Compositions according to any one of Claims and 4, characterised in that the said comonomer is chosen from the group consisting of derivatives of a-hydroxyacids, derivatives of a-aminoacids, especially of carboxy-anhydrides of a-aminoacids such as those of alanine, and lactones such as p-methyi-propioiactone.
Claim 7
Dependent Claim
43 words
Compositions according to any one of the preceding claims, characterised in that the matrix is botained from a poly(lactic acid) or a copolymer of lactic acid, of high molecular weight, such that the mean molecular mass is greater than or equal to 80,000.
Claim 8
Dependent Claim
19 words
Compositions according to Claim 6, characterised in that the said molecular mass is greater than or equal to 100,000.
Claim 9
Dependent Claim
29 words
Compositions according to any one of the preceding claims, characterised in that the reinforcing elements consist of a polymer having a molecular mass greater than or equal to 10,000.
Claim 10
Dependent Claim
17 words
Compositions according to Claim 8, characterised in that the said molecular mass is between 10,000 and 100,000.
Claim 11
Dependent Claim
20 words
Compositions according to any one of the preceding claims, characterised in that the reinforcing elements are made of polyglycolic acid.
Claim 12
Dependent Claim
29 words
Compositions according to any one of Claims 1 to 9, characterised in that the reinforcing elements consist of a copolymer of glycolic acid with a compatible and bioabsorbable comonomer.
Claim 13
Dependent Claim
27 words
Compositions according to Claim 11, characterised in that the said comonomer is chosen from the group consisting of lactic acid or lactide and its optically active forms.
Claim 14
Dependent Claim
43 words
Compositions according to either of Claims 11 and 12, characterised in that the said copolymer based on glycolic acid and used as a reinforcing element contains, in terms of number of units, at least 90 % of the units derived from glycolic acid.
Claim 15
Dependent Claim
35 words
Compositions according to any one of the preceding claims, characterised in that they are in the form of plates, nails or screws or in the form of solid blocks which can be moulded or machined.
Claim 16
Dependent Claim
37 words
Compositions according to any one of the preceding claims, characterised in that they contain a filler consisting of products containing at least one of the following ions : calcium, magnesium, sodium, potassium, phosphate, borate, carbonate and silicate.
Claim 17
Dependent Claim
31 words
Compositions according to Claim 15, characterised in that the filler is present in an amount of 0.5 to 5 % by weight relative to the total weight of the osteosynthesis piece.
Claim 18
Dependent Claim
82 words
Process for the preparation of a composition according to any one of the preceding claims, characterised in that the polymer constituting the matrix and the reinforcing elements are introduced in alternate layers into a compression mould, the whole is compressed under a suitable pressure and at a suitable temperature for a period of several minutes to give it the desired shape and dimensions, that thereafter it is cooled rapidly and that the piece is demoulded when the temperature is below 50 °C.
Claim 19
Dependent Claim
29 words
Process according to Claim 17, characterised in that the said pressure can vary between 20 and 500 kg/cm 2 (1.96 x 10 6 to 4.9 x 10 7 Pa).
Claim 20
Dependent Claim
23 words
Process according to any one of Claims 17 and 18, characterised in that the said temperature can vary from 170 to 200 °C.
Claim 21
Dependent Claim
30 words
Process according to any one of Claims 17 to 19, characterised in that the compression time is less than 7 minutes and is generally between 30 seconds and 7 minutes.
References Cited (Backward Citations)
No citation records indexed.
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