Patent US3143524A successfully refreshed from Google Patents.
Patent EP0003407A1 successfully refreshed from Google Patents.
EP0003407A1
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EP
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Pharmaceutical and dietary composition comprising gamma-linolenic acids
Assignee: Efamol Ltd
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Filing: 1979-01-17
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Granted: —
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Expires: 1999-01-17
Abstract
Abstract Compositions and use of y-linolenic acids and related materials in association with zinc and or β-lactam antibiotics to treat schizophrenia, obesity, menstrual disorders, skin disorders and other conditions.
Inventors
- 👤 David Frederick Horrobin
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-27 11:42
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/41; A61K31/425; A61K31/429; A61K31/43; A61K31/54; A61K31/542; A61K31/545; A61K33/00; A61K33/24; A61K33/30; A61P; A61P13/00; A61P13/02; A61P15/00; A61P17/00; A61P25/00; A61P25/18; A61P3/00; A61P3/04; A61P43/00
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
45 words
A pharmaceutical or dietary composition comprising (a) y-linolenic acid or physiologically functional derivative thereof and/or dihomo-y-linolenic acid or physiologically functional derivative thereof and a conjoint amount of (b) physiologically assimilable zinc and/or (c) a β-lactam antibiotic, alone or in an acceptable pharmaceutical or dietary vehicle.
Claim 2
Dependent Claim
45 words
A pharmaceutical or dietary composition comprising (a) y-linolenic acid or physiologically functional derivative thereof and/or dihomo-y-linolenic acid or physiologically functional derivative thereof and a conjoint amount of (b) physiologically assimilable zinc and/or (c) a β-lactam antibiotic, alone or in an acceptable pharmaceutical or dietary vehicle.
Claim 3
Dependent Claim
42 words
The composition of claim 1, presented for administration in doses comprising 0.05 to 10 g of (a) calculated as linolenic acid and 2.5 to 800 mg of (b) calculated as zinc, cr one half one third or one quarter of said amounts.
Claim 4
Dependent Claim
42 words
The composition of claim 1, presented for administration in doses comprising C.1 to 5 g of (a) calculated as linolenic acid and 10 to 200 mg of (b) calculated as zinc or one half one third or one quarter of said amounts.
Claim 5
Dependent Claim
42 words
The composition of claim 1, presented for administration in doses comprising 0.1 to 2 g of (a) calculated as linolenic acid and 10 to 200 mg of (b) calculated as zinc, or one half one third or one quarter of said amounts.
Claim 6
Dependent Claim
42 words
The composition of claim 1, presented for administration in doses comprising 0.1 to 1 g of (a) calculated as linolenic acid and 10 to 200 mg of (b) calculated as zinc, or one half one third or one quarter of said amounts.
Claim 7
Dependent Claim
18 words
The composition of claim 3, 4 or 5, wherein the amount of (b) is 10 to 80 mg.
Claim 8
Dependent Claim
17 words
The composition of claim 1, wherein the antibiotic is a natural or semi-synthetic penicillin or cephalosporin antibiotic.
Claim 9
Dependent Claim
24 words
The composition of claim 7, wherein the antibiotic is selected from penicillin G, penicillin N, penicillin V, cephalothin, ampicillin, amoxycillin, clcxacillin, cephalexin and cephalogylcin.
Claim 10
Dependent Claim
41 words
The composition of claim 7 or 8, presented for administration in doses comprising 0.05 to 10 g of (a) calculated as linolenic acid and 0.5 to 3 g of (c), or one half one third or one quarter of said amounts.
Claim 11
Dependent Claim
41 words
The composition of claim 7 or 8, presented for administration in doses comprising 0.1 to 5 g of (a) calculated as linolenic acid and 0.5 to 3 g of (c), or one half one third or one quarter of said amounts.
Claim 12
Dependent Claim
41 words
The composition of claim 7 or 8, presented for administration in doses comprising 0.1 to 2 g of (a) calculated as linolenic acid and 0.5 to 3 g of (c), or one half one third or one quarter of said amounts.
Claim 13
Dependent Claim
41 words
The composition of claim 7 or 8, presented for administration in doses comprising 0.1 to 1 g of (a) calculated as linolenic acid. and 0.5 to 3 g of (c), or one half one third or one quarter of said amounts.
Claim 14
Dependent Claim
25 words
The composition of any one of claims 7 to 12, containing the amounts of (b) set out in any one of claims 2 to 6.
Claim 15
Dependent Claim
27 words
A composition according to any preceding claim, wherein the physiologically functional derivative of y-linolenic acid or dihomo-y-linolenic acid is a methyl or ethyl ester or glyceride thereof.
Claim 16
Dependent Claim
41 words
A composition according to any one of claims 1 to 13 wherein the y-linolenic acid is present in the form of the oil of the seed of Oenothera biennis L, Oenothera lamarckiana, or other Evening Primrose species, or a fraction thereof.
Claim 17
Dependent Claim
37 words
A composition according to any one of claims 1 to 13, wherein the y-linolenic acid is present in the form of the oil of the seed of Borago officinalis or other Borage species, or a fraction thereof.
Claim 18
Dependent Claim
41 words
A composition according to any preceding claim specifying the presence of zinc, wherein the zinc is present as a salt of a mineral or organic acid (and in particular zinc oleate, zinc y-linolenate or zinc dihomo-γ-linolenate), zinc oxide, or chelated zinc.
Claim 19
Dependent Claim
20 words
A composition according to any preceding claim, comprising further an effective and pharmaceutically acceptable amount of a-tocopherol or other antioxidant.
Claim 20
Dependent Claim
38 words
A pharmaceutical or dietary pack comprising (a) and (b) and/or (c) as set out in any one of claims 1, 7, 8 and 14 to 17, presented separately or two together and one separately but for conjoint administration.
Claim 21
Dependent Claim
35 words
A pack according to claim 19 wherein (a) and (b) and/or (c) are presented for administration in the relative amounts set out in the respective claim(s) of claims 2 to 6 and 9 to 12.
References Cited (Backward Citations)
FR2272684A1
Cited
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