Patent CA1255989A successfully refreshed from Google Patents.
CA1255989A
Expired / Lapsed
CA
⏱️ 0.0 years remaining
Method of treatment of the myocardium and catheter for retroinfusion of pharmacologic agents
Assignee: Individual
•
Filing: 1985-01-18
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Granted: 1989-06-20
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Expires: 2005-01-18
Abstract
Abstract ABSTRACT OF THE DISCLOSURE METHOD OF TREATMENT OF THE MYOCARDIUM AND CATHETER FOR RETROINFUSION OF PHARMOCOLOGIC AGENTS An inflatable catheter and method of medical treatment in which the flexible balloon material stretches when inflated to produce an acorn-shaped balloon, the broadened base of which seals against the vein interfacing the coronary sinus orifice of the heart to allow for stoppage of the natural flow of blood in the vessel, and which facilitates antero-grade controlled, synchronous retroinfusion of pharmacologic or angiographic agents into the myocardium. An inflated catheter and method of medical treatment in which the apex of the inflated acorn-shaped balloon tapers away from the walls of the coronary sinus to prevent blockage of fluid flow through the middle cardiac vein thereby preventing pressure build up and edema in the myocardium.
Inventors
- 👤 Eliot Corday
- 👤 Samuel Meerbaum
Bibliographic Details
Application Number
—
Jurisdiction
CA
Data Source
google_patents
Last Synchronized
2026-10-23 22:58
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/1002; A61M2025/1043; A61M2025/1052
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
214 words
A system for the retrograde delivery of fluid containing pharmacologic or diagnostic fluids to a microcir-culatory system in a desired location within a patient's body comprising: a. a catheter having an inflatable balloon at the distal end thereof and adapted to be inserted into and advanced through a patient's venous system to a position in a vein which drains the microcirculatory system; b. means to inflate the balloon to thereby block the interior of the vein and prevent the fluid from flowing in the vein in the same direction as normal blood out-flow; c. means to direct fluid containing pharmacologic or diagnostic agents through the catheter and the vein and into the microcirculatory system in a retrograde direction which is opposite to the normal blood flow therethrough; d. means for maintaining the fluid containing pharma-cologic or diagnostic agents in the microcirculatory system for a period of time of at least two seconds and at sufficient pressure to facilitate the delivery of the fluid to the desired location and the desired performance of the pharma-cologic or diagnostic agent contained therein; and e. means to deflate the balloon at the distal end of the catheter to allow the fluid to drain from the micro-circulatory system through the vein in the direction of normal blood flow therein.
Claim 2
Independent Claim
214 words
A system for the retrograde delivery of fluid containing pharmacologic or diagnostic fluids to a microcir-culatory system in a desired location within a patient's body comprising: a. a catheter having an inflatable balloon at the distal end thereof and adapted to be inserted into and advanced through a patient's venous system to a position in a vein which drains the microcirculatory system; b. means to inflate the balloon to thereby block the interior of the vein and prevent the fluid from flowing in the vein in the same direction as normal blood out-flow; c. means to direct fluid containing pharmacologic or diagnostic agents through the catheter and the vein and into the microcirculatory system in a retrograde direction which is opposite to the normal blood flow therethrough; d. means for maintaining the fluid containing pharma-cologic or diagnostic agents in the microcirculatory system for a period of time of at least two seconds and at sufficient pressure to facilitate the delivery of the fluid to the desired location and the desired performance of the pharma-cologic or diagnostic agent contained therein; and e. means to deflate the balloon at the distal end of the catheter to allow the fluid to drain from the micro-circulatory system through the vein in the direction of normal blood flow therein.
Claim 3
Dependent Claim
28 words
The system of claim 1, further characterized by means to maintain the fluid in the microcirculatory system at sufficient pressure for a minimum period of about two seconds.
Claim 4
Dependent Claim
29 words
The system of claim 2, further characterized by means to maintain the fluid in the microcirculatory system for a minimum period of about 2 seconds to about 10 minutes.
Claim 5
Dependent Claim
41 words
The system of claim 1, further characterized by means to deflate the inflated balloon when the pressure of the fluid exceeds a predetermined maximum to drain fluid through the vein in the direction of normal blood flow and thereby relieve pressure.
Claim 6
Dependent Claim
26 words
The system of claim 1, further characterized by the inflated balloon at the distal end of the catheter having a broad base and a tapered apex.
Claim 7
Dependent Claim
15 words
The system of claim 5, further characterized by the inflated balloon having an acorn-like shape.
Claim 8
Dependent Claim
26 words
The system of claim 1, further characterized by the inflatable balloon being fixed to the outer periphery of the catheter and in a sealed relationship therewith.
Claim 9
Dependent Claim
48 words
The system of claim 7, further characterized by that portion of the catheter passing through the balloon being provided with one or more openings to allow for the direct pressure communication of the pharmacologic or diagnostic fluid with the interior of the balloon to thereby inflate the balloon.
Claim 10
Dependent Claim
48 words
The system of claim 7, further characterized by the catheter being provided with an additional conduit which passes into and terminates in the interior of the balloon and being adapted to direct fluid into and from the interior of the balloon to thereby inflate and deflate the balloon.
Claim 11
Dependent Claim
35 words
The system of claim 1, further characterized by means being provided to deliver fluid through the catheter and vein and into a microcirculatory system of the patient's myocardium when the heart thereof is in diastole.
Claim 12
Dependent Claim
18 words
The system of claim 8, further characterized by an electrocardiograph to determine when the heart is in diastole.
Claim 13
Dependent Claim
28 words
The system of claim 6, further characterized by the apex of the balloon being positioned from about 1 to 4 cm from the distal end of the catheter.
Claim 14
Dependent Claim
33 words
The system of claim 10, further characterized by means to deliver fluid through the catheter and the vein and into the microcirculatory system when the heart is in diastole having a synchronous pump.
Claim 15
Dependent Claim
13 words
The system of claim 3, further characterized by means to monitor fluid pressure.
Claim 16
Dependent Claim
35 words
The system of claim 14, further characterized by means to terminate or reduce fluid flow through the catheter when the means to monitor pressure indicates that the fluid pressure sensed exceeds a predetermined maximum pressure.
Claim 17
Dependent Claim
89 words
A coronary vascular catheter comprising an elongated hollow tubular body having a fluid delivery conduit therein which is in fluid communication with an opening thereof at the proximal end of the catheter and one or more openings at the distal end thereof and characterized by an inflatable balloon in a permanently fixed position on the hollow tubular body close to the distal end thereof having, when inflated, a broad base which tapers in the distal direction to the apex thereof producing an anatomically conforming seal within a coronary vessel.
Claim 18
Dependent Claim
89 words
A coronary vascular catheter comprising an elongated hollow tubular body having a fluid delivery conduit therein which is in fluid communication with an opening thereof at the proximal end of the catheter and one or more openings at the distal end thereof and characterized by an inflatable balloon in a permanently fixed position on the hollow tubular body close to the distal end thereof having, when inflated, a broad base which tapers in the distal direction to the apex thereof producing an anatomically conforming seal within a coronary vessel.
Claim 19
Dependent Claim
28 words
The catheter of claim 16, further characterized by the apex of the balloon being disposed from about 1 to 4 cm from the distal end of the catheter.
Claim 20
Dependent Claim
35 words
The catheter of claim 16, further characterized by a conduit being provided integral with the tubular body which has an opening into the interior of the balloon to facilitate inflation and deflation of the balloon.
Claim 21
Dependent Claim
50 words
The catheter of claim 16, further characterized by the tubular body passing through the interior of the balloon and being provided with one or more openings which allow passage of fluid between the hollow tubular body and the interior of the inflatable balloon to thereby inflate or deflate the balloon.
Claim 22
Dependent Claim
91 words
The catheter of claim 16, further characterized by a conduit being provided integral with the tubular body which extends along a substantial length of the catheter and has an opening at the distal and of the tubular body which is in fluid communication with fluid surrounding the distal end of the catheter and having another opening at or near the proximal end of the catheter adpated to be operatively connected to a pressure sensing means whereby the pressure of the fluid at the distal end of the catheter may be sensed.
Claim 23
Independent Claim
109 words
A system for the retroperfusion of fluid to a jeopardized, ischemic organ or area of a patient's body which includes a vascular catheter having an elongated, hollow, tubular body, a means to pump fluid therethrough in a pulsatile manner with the individual pulses of fluid synchronized to occur during the heart diastole, the system characterized by the catheter having the tubular body provided with an inflatable balloon in a permanently fixed position on the hollow tubular body close to the distal end thereof which, when inflated, has a broad base which tapers in the distal direction to the apex thereof and produces an anatomically conforming seal within a vessel.
Claim 24
Independent Claim
109 words
A system for the retroperfusion of fluid to a jeopardized, ischemic organ or area of a patient's body which includes a vascular catheter having an elongated, hollow, tubular body, a means to pump fluid therethrough in a pulsatile manner with the individual pulses of fluid synchronized to occur during the heart diastole, the system characterized by the catheter having the tubular body provided with an inflatable balloon in a permanently fixed position on the hollow tubular body close to the distal end thereof which, when inflated, has a broad base which tapers in the distal direction to the apex thereof and produces an anatomically conforming seal within a vessel.
Claim 25
Dependent Claim
13 words
The system of claim 21, further characterized by the inflated balloon being acorn-shaped.
References Cited (Backward Citations)
No citation records indexed.
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