Occlusion of channels in living mammals

Abstract

Abstract Methods for occluding channels in living mammals make use of thermoplastic polymeric compositions which melt just above normal body temperatures. The molten composition is injected into the channel and solidifies in situ. Preferred compositions contain side chain crystallizable (SCC) polymers, particularly thermoplastic elastomers containing SCC hard blocks, which melt at 34-45 °C. An injecting device for use in the method is illustrated and contains a reservoir for the occluding composition, an electrical heater for heating the composition, an injection nozzle, and a plunger for extruding molten composition through the nozzle. The invention is particularly useful for blocking tear ducts in the treatment of dry eye syndrome.

Inventors

• 👤 Edward E. Schmitt

Bibliographic Details