WO1992007573A1
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Genetic modification of endothelial cells
Assignee: The Brigham and Women's Hospital Inc
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Filing: 1991-10-31
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Granted: —
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Expires: 2011-10-31
Abstract
Abstract Endothelial cells transduced with genetic material encoding a polypeptide or protein of interest and, optionally, a selectable marker, as well as methods for making and using the transduced endothelial cells are disclosed. Such endothelial cells are useful in improving the performance of vascular grafts and in delivering the encoded polypeptide or protein, such as an enzyme, a hormone, a receptor or a drug, to an individual.
Inventors
- 👤 Lori F. Rafield
- 👤 Lawrence K. Cohen
- 👤 Allan D. Callow
- 👤 Louis K. Birinyi
- 👤 James M. Wilson
- 👤 Richard C. Mulligan
Bibliographic Details
Application Number
—
Jurisdiction
WO
Data Source
google_patents
Last Synchronized
2026-10-23 10:45
CPC Classifications
C; C12; C12N; C12N15/00; C12N15/09; C12N15/63; C12N15/79; C12N15/85; C12N15/86; A; A61; A61K; A61K35/00; A61K35/12; A61K35/44; A61L; A61L27/00; A61L27/36; A61L27/38; A61L33/00; A61L33/18; C07; C07K; C07K14/00; C07K14/435; C07K14/575; C07K14/635; C07K14/705; C07K14/745; C07K14/755; C12N5/00; C12N5/06; C12N5/0602; C12N5/069; C12N9/00; C12N9/14; C12N9/24; C12N9/2402; C12N9/2468; C12N9/2471; C12N9/48; C12N9/50; C12N9/64; C12N9/6421; C12N9/6424; C12N9/6456; C12N9/6459; C12Y; C12Y302/00; C12Y302/01; C12Y302/01023; C12Y304/00; C12Y304/21; C12Y304/21069; A61K2035/124; A61K38/00; A61K48/00; C12N2740/00; C12N2740/00011; C12N2740/10011; C12N2740/13011; C12N2740/13041; C12N2740/13043
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