US7806871B2
Expired / Lapsed
US
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Method and device for tissue removal and for delivery of a therapeutic agent or bulking agent
Assignee: Boston Scientific Scimed Inc
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Filing: 2005-05-09
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Granted: 2010-10-05
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Expires: 2025-05-09
Abstract
Abstract According to an aspect of the present invention, a medical device is provided, which comprises the following: (a) a hollow elongate body (e.g., a elongate cylinder, such as a needle) having distal and proximal ends; and (b) a rotatable member comprising a tissue morselizer and an elongate shaft (e.g., an auger-like tissue-drilling bit). The device (i) advances material (e.g., morselated tissue) toward the proximal end of the hollow elongate body when the shaft is rotated in a first direction, and (ii) advances material (e.g., a therapeutic agent and/or a bulking agent) toward the distal end of the hollow elongate body when the shaft is rotated in a second direction that is opposite the first direction. The invention also provides a method of treatment for morselizing and removing tissue from within the patient and creating a void within the patient and introducing a therapeutic agent and/or a bulking agent into the void.
Inventors
- 👤 Jamie (Jianmin) Li
- 👤 Weenna Bucay-Couto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 22:55
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/32; A61B17/320016; A61B17/32002; A61M; A61M37/00; A61B17/22; A61B10/00; A61B10/02; A61B10/0233; A61B10/0241; A61B17/00234; A61B2017/00238; A61B2017/00274; A61B2017/00681; A61B2017/00685; A61B17/3205; A61B17/3207; A61B17/320758; A61B2017/320775; A61B18/00; A61B2018/00315; A61B2018/00547
Claims Analysis
Total Claims: 32
Claim 1
Independent Claim
136 words
A medical device comprising: (a) a hollow elongate body having an open distal end, a proximal end, and a side port adjacent the distal end; and (b) a rotatable member having an elongate shaft with a raised helical blade having a cutting edge extending along at least a portion of the elongate shaft, the raised helical blade extending laterally outward from the elongate shaft, and with a tissue morselizer that includes a drill bit with a tissue-morselizing tip, said elongate shaft disposed in part within said hollow elongate body and extendable at least in part through the open distal end, wherein rotation of the rotatable member in a first direction causes the tip to morselize tissue or material and progressive movement of the helical blade severs tissue or material that is engaged with the side port.
Claim 2
Dependent Claim
136 words
A medical device comprising: (a) a hollow elongate body having an open distal end, a proximal end, and a side port adjacent the distal end; and (b) a rotatable member having an elongate shaft with a raised helical blade having a cutting edge extending along at least a portion of the elongate shaft, the raised helical blade extending laterally outward from the elongate shaft, and with a tissue morselizer that includes a drill bit with a tissue-morselizing tip, said elongate shaft disposed in part within said hollow elongate body and extendable at least in part through the open distal end, wherein rotation of the rotatable member in a first direction causes the tip to morselize tissue or material and progressive movement of the helical blade severs tissue or material that is engaged with the side port.
Claim 3
Dependent Claim
22 words
The medical device of claim 1 , wherein said distal end of said hollow elongate body is adapted for penetration of tissue.
Claim 4
Dependent Claim
16 words
The medical device of claim 1 , wherein said hollow elongate body comprises a hollow needle.
Claim 5
Dependent Claim
19 words
The medical device of claim 3 , wherein said hollow needle is a 10 to 22 gauge hollow needle.
Claim 6
Dependent Claim
19 words
The medical device of claim 3 , wherein said hollow needle is a 12 to 18 gauge hollow needle.
Claim 7
Dependent Claim
16 words
The medical device of claim 1 , wherein said tissue morselizer is adapted to grind tissue.
Claim 8
Dependent Claim
16 words
The medical device of claim 1 , wherein said tissue morselizer is adapted to slice tissue.
Claim 9
Dependent Claim
21 words
The medical device of claim 1 , wherein said rotatable member is axially moveable with respect to said hollow elongate body.
Claim 10
Dependent Claim
25 words
The medical device of claim 1 , wherein said tissue morselizer is adapted to morselize tissue at the distal end of said hollow elongate body.
Claim 11
Dependent Claim
48 words
The medical device of claim 1 , wherein said medical device is adapted for insertion into a body lumen and wherein said distal end of said hollow elongate member is adapted to pierce the wall of the body lumen and access a tissue region proximate the body lumen.
Claim 12
Dependent Claim
30 words
The medical device of claim 1 , further comprising at least one of a vacuum source and irrigation source, in communication with the proximal end of said hollow elongate body.
Claim 13
Dependent Claim
24 words
The medical device of claim 1 , further comprising a tissue collection container in communication with the proximal end of said hollow elongate body.
Claim 14
Dependent Claim
35 words
The medical device of claim 1 , wherein the material comprises a therapeutic agent or bulking agent, wherein said therapeutic agent is selected from anticoagulants, analgesics, antispasmodic agents, hemostatic agents, necrosis agents and antineoplastic agents.
Claim 15
Dependent Claim
32 words
The medical device of claim 1 , wherein the material comprises a therapeutic agent or bulking agent, wherein said therapeutic agent or said bulking agent is in a liquid or semi-liquid form.
Claim 16
Dependent Claim
32 words
The medical device of claim 1 , wherein the material comprises a therapeutic agent or bulking agent, wherein said therapeutic agent or said bulking agent is in a solid or semi-solid form.
Claim 17
Dependent Claim
33 words
The medical device of claim 1 , wherein the material comprises a therapeutic agent or bulking agent, wherein said therapeutic agent or said bulking agent is in particulate, granulated or pelletized dosage form.
Claim 18
Dependent Claim
56 words
A method of treatment comprising: inserting the medical device of claim 1 into tissue of a patient; morselizing and removing tissue from within said patient while rotating said shaft in a first direction, thereby creating a void within the patient; and introducing at least one of a therapeutic agent or a bulking agent into the void.
Claim 19
Dependent Claim
31 words
The method of claim 17 , wherein the therapeutic agent, the bulking agent, or both are introduced while rotating said shaft in a second direction that is opposite said first direction.
Claim 20
Dependent Claim
16 words
The method of claim 17 , wherein said tissue removal is enhanced by applying a vacuum.
Claim 21
Dependent Claim
18 words
The method of claim 17 , wherein the tissue is selected from prostate, brain, and soft cancer tissue.
Claim 22
Dependent Claim
24 words
The method of claim 17 , wherein said therapeutic agent is selected from anticoagulants, analgesics, antispasmodic agents, hemostatic agents, necrosis agents and antineoplastic agents.
Claim 23
Dependent Claim
20 words
The medical device of claim 1 , wherein said elongate shaft further comprises a central lumen for passage of fluids.
Claim 24
Dependent Claim
17 words
The medical device of claim 1 , wherein the material comprises a therapeutic agent or bulking agent.
Claim 25
Dependent Claim
26 words
The medical device of claim 1 , wherein the device further comprises a fluid pump in communication with the proximal end of the hollow elongate body.
Claim 26
Dependent Claim
36 words
The medical device of claim 24 , wherein the device further comprises a container for containing a therapeutic agent or a bulking agent in liquid or semi-liquid form, said container in communication with said fluid pump.
Claim 27
Dependent Claim
13 words
The medical device of claim 25 , wherein said container comprises an ampoule.
Claim 28
Dependent Claim
58 words
The medical device of claim 1 , wherein the material comprises a therapeutic agent or bulking agent, wherein said therapeutic agent comprises analgesics further comprising opioid analgesics comprising codeine, fentanyl, meperidine, methadone, morphine, pentazocine, and tramadol, non-opioid analgesics comprising etodolac, fenoprofen, ketoprofen, ketorolac, mefenamic acid, paracetamol, and piroxicam, non-steroidal anti-inflammatory drugs comprising aspirin, diclofenac, ibuprofen, indomethacin, and naproxen.
Claim 29
Dependent Claim
15 words
The medical device of claim 1 wherein the elongate shaft is an untapered elongate shaft.
Claim 30
Dependent Claim
199 words
A medical device comprising: (a) a hollow elongate body having an open distal end and a proximal end; (b) a rotatable member having a tissue morselizer at its distal end that includes a drill bit with a tissue-morselizing tip and an elongate shaft provided with a raised helix extending laterally outward from the elongate shaft, said elongate shaft being disposed in part within said hollow elongate and extendable at least in part through the open distal end, wherein the raised helix engages with tissue or a material occupying voids between the raised helix of the elongate shaft to (i) advance the tissue or the material toward the proximal end of said hollow elongate body when said shaft is rotated in a first direction, and (ii) advance the tissue or the material toward the distal end of said hollow elongate body when said shaft is rotated in a second direction that is opposite said first direction; and (c) a side port located in the hollow elongate body adjacent the distal end and configured to receive tissue or material therein so that the tissue or material can be severed by progressive movement of the raised helix within the hollow elongate body.
Claim 31
Dependent Claim
199 words
A medical device comprising: (a) a hollow elongate body having an open distal end and a proximal end; (b) a rotatable member having a tissue morselizer at its distal end that includes a drill bit with a tissue-morselizing tip and an elongate shaft provided with a raised helix extending laterally outward from the elongate shaft, said elongate shaft being disposed in part within said hollow elongate and extendable at least in part through the open distal end, wherein the raised helix engages with tissue or a material occupying voids between the raised helix of the elongate shaft to (i) advance the tissue or the material toward the proximal end of said hollow elongate body when said shaft is rotated in a first direction, and (ii) advance the tissue or the material toward the distal end of said hollow elongate body when said shaft is rotated in a second direction that is opposite said first direction; and (c) a side port located in the hollow elongate body adjacent the distal end and configured to receive tissue or material therein so that the tissue or material can be severed by progressive movement of the raised helix within the hollow elongate body.
Claim 32
Dependent Claim
15 words
The medical device of claim 29 wherein the elongate shaft is an untapered elongate shaft.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2013-10-04 | 2014-04-05 | 2014-10-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2017-10-04 | 2018-04-05 | 2018-10-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2021-10-04 | 2022-04-05 | 2022-10-05 | $7700.00 | Window Closed / Lapsed |