Device for reduction of pressure effects of cardiac tricuspid valve regurgitation

Claim 2

An elongate valve stent comprising: a first stent member comprising a first support structure including a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut and a first tissue valve disposed thereon, said first tissue valve including at least two leaflets structured to open and close permitting the flow of blood therethrough in the open position; a second stent member distinct and separated from said first stent member by a predetermined distance, said second stent member comprising a second support structure including a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut and a second tissue valve disposed thereon, said second tissue valve including at least two leaflets structured to open and close permitting the flow of blood therethrough in the open position; and at least two elongate connecting members extending between and connecting at least one serpentine band of the first stent member to at least one serpentine band of the second stent member.

Claim 3

The elongate valve stent of claim 1 , wherein said first tissue valve is configured to permit fluid flow towards the middle section and prevent fluid flow in an opposite direction.

Claim 4

The elongate valve stent of claim 1 , wherein said second tissue valve is configured to permit fluid flow towards the middle section and prevent fluid flow in an opposite direction.

Claim 5

The elongate valve stent of claim 1 , wherein said first tissue valve is configured to permit fluid flow towards the middle section and the second tissue valve is configured to permit fluid flow from the middle section towards the second end.

Claim 6

The elongate valve stent of claim 1 , wherein the first and second support structures are collapsibly expandable from a first collapsed position to a second expanded position.

Claim 7

The elongate valve stent of claim 5 , wherein a circumference of the first support structure at the expanded position is equal to a circumference of the second support structure at the expanded position.

Claim 8

The elongate valve stent of claim 5 , wherein a circumference of the first support structure at the expanded position is larger than a circumference of the second support structure at the expanded position.

Claim 9

The elongate valve stent of claim 1 , wherein both support structures of said stent are self-expandable.

Claim 10

The elongate valve stent of claim 1 , wherein the first or second support structure of said stent is expandable by an inflatable balloon.

Claim 11

The elongate valve stent of claim 1 , wherein the first or second support structure of said stent is made of a shape-memory material having a first shape transition temperature of between about 30.degree. C. and 45.degree. C. and a second shape transition temperature of about 5.degree. C. and −10.degree. C., said support structure being collapsibly deformed to below the second shape transition temperature during delivery and expanded after delivery in place upon reaching the first shape transition temperature.

Claim 12

The elongate valve stent of claim 1 , wherein said at least two leaflets are made from a pericardium.

Claim 13

The elongate valve stent of claim 11 , wherein the pericardium is selected from a group consisting of a bovine pericardium, an equine pericardium, a porcine pericardium, and an ovine pericardium.

Claim 14

The elongate valve stent of claim 1 , wherein said at least two leaflets are chemically treated by a chemical treating agent selected from a group consisting of glutaraldehyde, formaldehyde, dialdehyde starch, epoxy compounds, genipin, and mixture thereof.

Claim 15

The elongate valve stent of claim 1 , wherein said first or second tissue valve is a venous valve procured from a group consisting of a bovine jugular vein, an equine jugular vein, a porcine jugular vein, and an ovine jugular vein.

Claim 16

The elongate valve stent of claim 1 , wherein said first or second tissue valve is a porcine valve.

Claim 17

The elongate valve stent of claim 1 , wherein the elongate connecting members are essentially parallel to each other or in a spiral shape.

Claim 18

The elongate valve stent of claim 1 , wherein said first or second support structure is made of a material selected from a group consisting of stainless steel, Nitinol, and plastics.

Claim 19

The elongate valve stent of claim 1 , wherein said first or second support structure is coated with a therapeutic agent.

Claim 20

The elongate valve stent of claim 18 , wherein said therapeutic agent is selected from a group consisting of anticoagulants, antithrombogenic agents, anti-proliferative agents, anti-inflammatory agents, antibiotics, stem cells, growth factors, angiogenesis agents, anti-angiogenesis agents, and statins.

Claim 21

The elongate valve stent of claim 1 , wherein said first or second support structure further comprises means for anchoring said first or second support structure onto surrounding tissue of either the superior vena cava or the inferior vena cava.

Claim 22

The elongate valve stent of claim 1 , wherein the at least one elongate connecting member comprises a length that is adjustable.

Claim 23

The elongate valve stent of claim 1 wherein said first stent member is configured to be implanted in a superior vena cava.

Claim 24

The elongate valve stent of claim 1 wherein said second stent member is configured to be implanted in an inferior vena cava.

Claim 25

The elongate valve stent of claim 1 wherein said first stent member is configured to be implanted in a superior vena cava and said second stent member is configured to be implanted in an inferior vena cava.

Claim 26

A elongate valve stent for protecting an upper body and a lower body of a patient from high venous pressures comprising: a first stent member comprising a first support structure including a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut and a first tissue valve disposed thereon, said first tissue valve structured to be implanted in a superior vena cava and including at least two leaflets structured to open and close permitting the flow of blood therethrough in the open position; a second stent member distinct and separate from said first stent member, said second stent member comprising a second support structure including a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut and a second tissue valve disposed thereon, said second tissue valve structured to be implanted in an inferior vena cava and including at least two leaflets structured to open and close permitting the flow of blood therethrough in the open position; and at least one elongate connecting member extending between and connecting at least one serpentine band of the first stent member to at least one serpentine band of the second stent member wherein said first and second valves are configured to permit blood flow towards a right atrium and prevent blood flow in an opposite direction.

Claim 27

A elongate valve stent for protecting an upper body and a lower body of a patient from high venous pressures comprising: a first stent member comprising a first support structure including a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut and a first tissue valve disposed thereon, said first tissue valve structured to be implanted in a superior vena cava and including at least two leaflets structured to open and close permitting the flow of blood therethrough in the open position; a second stent member distinct and separate from said first stent member, said second stent member comprising a second support structure including a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut and a second tissue valve disposed thereon, said second tissue valve structured to be implanted in an inferior vena cava and including at least two leaflets structured to open and close permitting the flow of blood therethrough in the open position; and at least one elongate connecting member extending between and connecting at least one serpentine band of the first stent member to at least one serpentine band of the second stent member wherein said first and second valves are configured to permit blood flow towards a right atrium and prevent blood flow in an opposite direction.

Claim 28

An elongate valve stent comprising: a first stent member comprising a first support structure including a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut and a first tissue valve disposed thereon; a second stent member separate and distinct from said first stent member, said second stent member comprising a second support structure including a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut and a second tissue valve disposed thereon; and at least one elongate connecting member sized and configured to provide radial flexibility and longitudinal stiffness, said elongate connecting member extending between and connecting at least one serpentine band of the first stent member to at least one serpentine band of the second stent member.

Claim 29

An elongate valve stent comprising: a first stent member comprising a first support structure including a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut and a first tissue valve disposed thereon; a second stent member separate and distinct from said first stent member, said second stent member comprising a second support structure including a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut and a second tissue valve disposed thereon; and at least one elongate connecting member sized and configured to provide radial flexibility and longitudinal stiffness, said elongate connecting member extending between and connecting at least one serpentine band of the first stent member to at least one serpentine band of the second stent member.