Patent US3155096A successfully refreshed from Google Patents.
US6532380B1
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Image guidance for coronary stent deployment
Assignee: Cedars-Sinai Medical Center
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Filing: 2000-06-30
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Granted: 2003-03-11
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Expires: 2020-06-30
Abstract
Abstract A method for image guidance of coronary stent deployment using radiopaque markers and the image processing technique of moving layer decomposition. The radiopaque markers are attached to guidewires or delivery balloons that are used to place the stent and co-moves with the coronary vessel. A series of fluoroscopic images are taken during the stent placement and are used to generate layer images which represent different structures in the angiograms, such as the stent and guidewires, background structures, etc. The clearly visible images of the markers are used in the layer decomposition. Although stents are less radiopaque than the markers, visibility of previously deployed stents is also enhanced in the layer images. The layer images are used to guide placement of multiple stents to prevent overlap or gaps between the stents. After stent expansion, angiographic images are acquired of the lumen filled with liquid contrast agent. Layer decomposition is applied to these images in order to visually or quantitatively determine the lumen narrowing (or broadening) in the stented region.
Inventors
- 👤 Robert A. Close
- 👤 James S. Whiting
- 👤 Craig K. Abbey
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:13
CPC Classifications
G; G06; G06T; G06T7/00; G06T7/0002; G06T7/0012; A; A61; A61B; A61B6/00; A61B6/48; A61B6/481; A61B6/50; A61B6/504; A61F; A61F2/00; A61F2/95; G06T5/00; G06T5/50; G06T7/20; G06T7/254; A61F2/958; A61M; A61M2205/00; A61M2205/50; A61M2205/52; G06T2207/00; G06T2207/30; G06T2207/30004; G06T2207/30101
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
168 words
A method for generating a visual image of a lumen of a coronary vessel and a device moving within the vessel, the method comprising: inserting radiopaque material into the vessel; obtaining a time series of images containing the vessel; and decomposing the time series of images into a sum of multiple moving layers wherein decomposing the time-series of images comprises selecting a reference image from an image frame within a first time-series of images; calculating from the first time-series of images a first motion function which maps each image to the reference image; calculating, by applying the first motion function for each image, a first layer image which is a time-average of the images moved into alignment with the reference image; generating a sequence of residual images by subtracting the first layer image from each image of the original sequence; calculating subsequent layer images by repeating the steps of selecting a reference image, calculating a motion function, calculating a layer image, and generating a sequence of residual images.
Claim 2
Independent Claim
168 words
A method for generating a visual image of a lumen of a coronary vessel and a device moving within the vessel, the method comprising: inserting radiopaque material into the vessel; obtaining a time series of images containing the vessel; and decomposing the time series of images into a sum of multiple moving layers wherein decomposing the time-series of images comprises selecting a reference image from an image frame within a first time-series of images; calculating from the first time-series of images a first motion function which maps each image to the reference image; calculating, by applying the first motion function for each image, a first layer image which is a time-average of the images moved into alignment with the reference image; generating a sequence of residual images by subtracting the first layer image from each image of the original sequence; calculating subsequent layer images by repeating the steps of selecting a reference image, calculating a motion function, calculating a layer image, and generating a sequence of residual images.
Claim 3
Dependent Claim
36 words
The method of claim 1 , wherein the device is selected from the group consisting of a stent, a catheter, a guidewire, an endoscope, an angioplasty balloon, an atherectomy cutting device, and an intravascular ultrasound device.
Claim 4
Dependent Claim
19 words
The method of claim 1 , wherein the radiopaque material comprises at least one marker attached to the device.
Claim 5
Dependent Claim
19 words
The method of claim 1 , wherein the radiopaque material comprises a liquid contrast agent injected into the vessel.
Claim 6
Dependent Claim
58 words
The method of claim 1 , wherein the method of decomposing the time-series of images further comprises refining a layer image calculation by subtracting from the layer image: a sequence formed from a subsequent layer image attenuated by dividing the number of images in the sequence moving with the difference between two layer motions for each time interval.
Claim 7
Dependent Claim
16 words
The method of claim 1 , wherein at least one motion function is set to zero.
Claim 8
Dependent Claim
17 words
The method of claim 1 , wherein at least one motion function is calculated using phase correlation.
Claim 9
Dependent Claim
17 words
The method of claim 1 , wherein at least one motion function is calculated using blurred images.
Claim 10
Dependent Claim
20 words
The method of claim 1 , further comprising using an image intensifier fluoroscope to obtain the time series of images.
Claim 11
Dependent Claim
22 words
The method of claim 1 , further comprising displaying layer-derived digital subtraction angiography and time-averaged digital subtraction angiography images on a display.
Claim 12
Independent Claim
206 words
A method for positioning at least one stent within a coronary vessel, the method comprising: inserting, with a delivery device, at least one stent into a coronary vessel, wherein the delivery device has at least one radiopaque marker; obtaining a time series of images containing the vessel; decomposing the time series of images into a sum of multiple moving layers; displaying, on a display, images selected from the group consisting of layer-derived digital subtraction angiography images and time-averaged digital subtraction angiography images; positioning the at least one stent within the vessel wherein decomposing the time-series of images comprises selecting a reference image from an image frame within a first time-series of images; calculating from the first time-series of images a first motion function which maps each image to the reference image; calculating, by applying the first motion function for each image, a first layer image which is a time-average of the images moved into alignment with the reference image; generating a sequence of residual images by subtracting the first layer image from each image of the original sequence; calculating subsequent layer images by repeating the steps of selecting a reference image, calculating a motion function, calculating a layer image, and generating a sequence of residual images.
Claim 13
Independent Claim
206 words
A method for positioning at least one stent within a coronary vessel, the method comprising: inserting, with a delivery device, at least one stent into a coronary vessel, wherein the delivery device has at least one radiopaque marker; obtaining a time series of images containing the vessel; decomposing the time series of images into a sum of multiple moving layers; displaying, on a display, images selected from the group consisting of layer-derived digital subtraction angiography images and time-averaged digital subtraction angiography images; positioning the at least one stent within the vessel wherein decomposing the time-series of images comprises selecting a reference image from an image frame within a first time-series of images; calculating from the first time-series of images a first motion function which maps each image to the reference image; calculating, by applying the first motion function for each image, a first layer image which is a time-average of the images moved into alignment with the reference image; generating a sequence of residual images by subtracting the first layer image from each image of the original sequence; calculating subsequent layer images by repeating the steps of selecting a reference image, calculating a motion function, calculating a layer image, and generating a sequence of residual images.
Claim 14
Dependent Claim
26 words
The method of claim 11 , further comprising the step of determining, by visually inspecting the display, the proper position of the at least one stent.
Claim 15
Dependent Claim
45 words
The method of claim 11 , wherein the step of positioning the at least one stent within the vessel further comprises positioning a first stent adjacent to a second stent such that there is no overlap and no gap between the first and second stents.
Claim 16
Dependent Claim
25 words
The method of claim 11 , wherein the delivery device is selected from the group consisting of a guidewire, a catheter, and an angioplasty balloon.
Claim 17
Dependent Claim
16 words
The method of claim 11 , further comprising injecting a liquid contrast agent into the vessel.
Claim 18
Dependent Claim
20 words
The method of claim 11 , further comprising using an image intensifier fluoroscope to obtain the time series of images.
Claim 19
Dependent Claim
58 words
The method of claim 11 , wherein the method of decomposing the time-series of images further comprises refining a layer image calculation by subtracting from the layer image: a sequence formed from a subsequent layer image attenuated by dividing the number of images in the sequence moving with the difference between two layer motions for each time interval.
Claim 20
Dependent Claim
16 words
The method of claim 11 , wherein at least one motion function is set to zero.
Claim 21
Dependent Claim
17 words
The method of claim 11 , wherein at least one motion function is calculated using phase correlation.
Claim 22
Dependent Claim
17 words
The method of claim 11 , wherein at least one motion function is calculated using blurred images.
References Cited (Backward Citations)
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Cited
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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