US6364905B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Tri-composite, full root, stentless valve
Assignee: Corcym SRL
•
Filing: 1999-07-23
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Granted: 2002-04-02
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Expires: 2019-07-23
Abstract
Abstract A bioprosthetic heart valve is disclosed. In a first aspect of the invention, a prosthetic heart valve comprises three mammalian heart valve leaflets, each valve leaflet including a full root length of tissue, the valve leaflets being affixed to one another to define a fluid flow passage, the fluid flow through which may be governed by the valve leaflets. In a second aspect the heart valve comprises a plurality of heart valve leaflets affixed to one another to define a fluid flow passage, the fluid flow through which may be governed by the valve leaflets; and a permanent trimming guide on at least one of the plurality of valve leaflets. In yet a third aspect of the invention, a bioprosthetic heart valve comprises a plurality of assembled parts, wherein the assembled parts are sutured together by hidden and locking stitches.
Inventors
- 👤 Charles L. Simpson
- 👤 Brian K. McIlroy
- 👤 Lisa G. O'Connor
- 👤 Ivan Casagrande
- 👤 Stephen Westaby
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:39
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/24; A61F2/2412; A61F2/2415; A61F2220/00; A61F2220/0025; A61F2220/0075; Y; Y10; Y10S; Y10S623/00; Y10S623/909; Y10S623/91
Claims Analysis
Total Claims: 42
Claim 1
Independent Claim
58 words
A prosthetic composite heart valve, comprising three mammalian heart valve leaflet sections, each leaflet section including a full root length of tissue and a valve leaflet and being devoid of coronary ostia, the leaflet sections being affixed to one another to define a fluid flow passage, the fluid flow through which may be governed by the valve leaflets.
Claim 2
Dependent Claim
58 words
A prosthetic composite heart valve, comprising three mammalian heart valve leaflet sections, each leaflet section including a full root length of tissue and a valve leaflet and being devoid of coronary ostia, the leaflet sections being affixed to one another to define a fluid flow passage, the fluid flow through which may be governed by the valve leaflets.
Claim 3
Dependent Claim
21 words
The prosthetic heart valve of claim 1 , wherein the leaflet sections are selected from the group comprising xenografts and homografts.
Claim 4
Dependent Claim
24 words
The prosthetic heart valve of claim 2 , wherein at least one of the valve leaflets is a xenograft comprising a porcine valve leaflet.
Claim 5
Dependent Claim
18 words
The prosthetic heart valve of claim 1 , wherein at least one of the valve leaflets is aortic.
Claim 6
Dependent Claim
18 words
The prosthetic heart valve of claim 1 , wherein at least one of the valve leaflets is pulmonary.
Claim 7
Dependent Claim
22 words
The prosthetic heart valve of claim 1 , wherein at least one of the valve leaflets is a non-coronary, xenograph valve leaflet.
Claim 8
Dependent Claim
35 words
The prosthetic heart valve of claim 1 , wherein at least one of the valve leaflets has been trimmed to exclude extraneous muscle tissue resulting in a void in said leaflet that has been trimmed.
Claim 9
Dependent Claim
21 words
The prosthetic heart valve of claim 7 , wherein the void resulting from muscle trimming is filled by the adjacent leaflet.
Claim 10
Dependent Claim
48 words
The prosthetic heart valve of claim 1 , wherein the full root length of tissue for at least one valve leaflet section extends 1-3 cm below an annulus defined by the valve leaflets in the fluid flow passage and 1-3 cm above the sinotubular junction of the aorta.
Claim 11
Dependent Claim
26 words
The prosthetic heart valve of claim 1 , further comprising a pericardial covering on at least one of the inflow end and the outflow end thereof.
Claim 12
Dependent Claim
16 words
The prosthetic heart valve of claim 10 , wherein the pericardium covering comprises a mammalian pericardium.
Claim 13
Dependent Claim
20 words
The prosthetic heart valve of claim 11 , wherein the pericardium covering is sutured to the valve using hidden stitching.
Claim 14
Dependent Claim
20 words
The prosthetic heart valve of claim 11 , wherein the pericardium covering is sutured to the valve using locking stitching.
Claim 15
Dependent Claim
20 words
The prosthetic heart valve of claim 11 , wherein the pericardium covering extends 1-15 cm the length of the valve.
Claim 16
Dependent Claim
31 words
The prosthetic heart valve of claim 11 , wherein the pericardium covering contains a stitch which facilitates surgeon suture placement by indicating where sutures can be placed without damaging the leaflets.
Claim 17
Dependent Claim
30 words
The prosthetic heart valve of claim 1 , wherein at least one of the valve leaflets is fixed using a technique selected from the group comprising gluteraldehyde fixation and photofixation.
Claim 18
Dependent Claim
26 words
The prosthetic heart valve of claim 1 , wherein the valve leaflets are affixed using a technique selected from the group comprising adhesion, fusion, and stitching.
Claim 19
Dependent Claim
18 words
The prosthetic heart valve of claim 1 , wherein the valve leaflets are affixed using a locking stitch.
Claim 20
Dependent Claim
21 words
The prosthetic heart valve of claim 17 , wherein the valve leaflets are affixed using a suture that will not unravel.
Claim 21
Dependent Claim
32 words
A tri-composite, full root, stentless heart valve, which is devoid of coronary ostia, wherein leaflet sections that are attached to form the tri-composite have been treated by photochemical fixation prior to assembly.
Claim 22
Dependent Claim
32 words
A tri-composite, full root, stentless heart valve, which is devoid of coronary ostia, wherein leaflet sections that are attached to form the tri-composite have been treated by photochemical fixation prior to assembly.
Claim 23
Dependent Claim
26 words
The valve of claim 20 wherein sutures are used to attach the sections wherein the sutures are sewn such that they do not unravel when cut.
Claim 24
Dependent Claim
18 words
The valve of claim 20 including a pericardial sewing ring attached to a posterior end of the valve.
Claim 25
Dependent Claim
14 words
The valve of claim 20 wherein the leaflet sections comprise porcine or bovine tissue.
Claim 26
Dependent Claim
13 words
The valve of claim 20 wherein the valve is made of porcine tissue.
Claim 27
Dependent Claim
89 words
A prosthetic heart valve comprising a tri-composite, full root, stentless valve, which is devoid of coronary ostia, and which has been made by suturing together three pieces of animal tissue that each includes a heart valve leaflet to form a tubular structure having an external surface, an inner surface, an posterior end, a anterior end, and in which the three leaflets have cusps and edges, with the adjacent edges of the valve leaflets meeting to form commissures, wherein the pieces have been treated by photochemical fixation prior to suturing.
Claim 28
Dependent Claim
89 words
A prosthetic heart valve comprising a tri-composite, full root, stentless valve, which is devoid of coronary ostia, and which has been made by suturing together three pieces of animal tissue that each includes a heart valve leaflet to form a tubular structure having an external surface, an inner surface, an posterior end, a anterior end, and in which the three leaflets have cusps and edges, with the adjacent edges of the valve leaflets meeting to form commissures, wherein the pieces have been treated by photochemical fixation prior to suturing.
Claim 29
Dependent Claim
26 words
The valve of claim 25 wherein sutures are used to attach the sections wherein the sutures are sewn such that they do not unravel when cut.
Claim 30
Dependent Claim
18 words
The valve of claim 25 including a pericardial sewing ring attached to a posterior end of the valve.
Claim 31
Dependent Claim
16 words
The valve of claim 25 wherein the leaflet sections are made of porcine or bovine tissue.
Claim 32
Dependent Claim
13 words
The valve of claim 25 wherein the valve is made of porcine tissue.
Claim 33
Dependent Claim
69 words
A process for the manufacture of a prosthetic heart valve, comprising: providing mammalian sections contain heart valve leaflets; treating the sections using photofixation; attaching three sections to define a tubular structure wherein the leaflets match to form commissures at adjacent edges of the leaflets; attaching a sewing ring at a posterior end of the tubular structure; thereby forming a full root, tri-composite, stentless heart valve devoid of coronary ostia.
Claim 34
Dependent Claim
69 words
A process for the manufacture of a prosthetic heart valve, comprising: providing mammalian sections contain heart valve leaflets; treating the sections using photofixation; attaching three sections to define a tubular structure wherein the leaflets match to form commissures at adjacent edges of the leaflets; attaching a sewing ring at a posterior end of the tubular structure; thereby forming a full root, tri-composite, stentless heart valve devoid of coronary ostia.
Claim 35
Dependent Claim
26 words
The process of claim 30 wherein sutures are used to attach the sections wherein the sutures are sewn such that they do not unravel when cut.
Claim 36
Dependent Claim
16 words
The process of claim 30 wherein the leaflet sections are made of porcine or bovine tissue.
Claim 37
Dependent Claim
13 words
The process of claim 30 wherein the valve is made of porcine tissue.
Claim 38
Dependent Claim
61 words
A process for the replacement of a heart valve in a human, comprising: removing an existing heart valve from the human and implanting a tri-composite, full root, stentless heart valve devoid of coronary ostia wherein leaflet sections that are sutured together to form the tri-composite have been treated by photochemical fixation prior to assembly in place of the existing heart valve.
Claim 39
Dependent Claim
61 words
A process for the replacement of a heart valve in a human, comprising: removing an existing heart valve from the human and implanting a tri-composite, full root, stentless heart valve devoid of coronary ostia wherein leaflet sections that are sutured together to form the tri-composite have been treated by photochemical fixation prior to assembly in place of the existing heart valve.
Claim 40
Dependent Claim
26 words
The process of claim 34 wherein sutures are used to attach the sections wherein the sutures are sewn such that they do not unravel when cut.
Claim 41
Dependent Claim
16 words
The process of claim 34 wherein the leaflet sections are made of porcine or bovine tissue.
Claim 42
Dependent Claim
13 words
The process of claim 34 wherein the valve is made of porcine tissue.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2005-04-01 | 2005-10-01 | 2006-04-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2009-04-01 | 2009-10-01 | 2010-04-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2013-04-01 | 2013-10-01 | 2014-04-02 | $7700.00 | Window Closed / Lapsed |