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US6203551B1 Expired / Lapsed US ⏱️ 0.0 years remaining

Chamber for applying therapeutic substances to an implant device

Assignee: Abbott Cardiovascular Systems Inc
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Filing: 1999-10-04
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Granted: 2001-03-20
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Expires: 2019-10-04
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Abstract

Abstract A chamber is provided that allows a user to medicate an implantable prosthesis such as a stent. The implantable prosthesis is capable of securing a therapeutic substance and subsequently delivering the therapeutic substance to local tissues. The chamber allows a user to medicate the prosthesis subsequent to the sterilization process and immediately prior to the implantation procedure. The chamber includes a hollow body defining a chamber cavity that encapsulates the prosthesis crimped on a balloon of a catheter assembly. The chamber is removably mounted on the catheter assembly. A user can supply therapeutic substances into the chamber and allow the therapeutic substances to be secured by the prosthesis. After allowing the prosthesis to be soaked by the therapeutic substances for a predetermined amount of time, the chamber is removed and the prosthesis is ready for the implantation procedure.

Inventors

  • 👤 Steven Z. Wu

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 19:29
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2/82; A61F2/86; A61F2/90; A61F2/91; A61F2250/00; A61F2250/0058; A61F2250/0067; B; B05; B05C; B05C3/00; B05C3/20

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 132 words
A chamber which allows a user to medicate implantable devices, comprising: (a) a hollow body defining a chamber cavity, said chamber cavity is configured to removably encapsulate an implantable device, said implantable device can be delivered to an anatomical lumen of a mammal for the delivery of a therapeutic substance to said mammal; (b) an inlet disposed in said hollow body, said inlet allows a user to supply a therapeutic substance into said chamber cavity, wherein said therapeutic substance contacts said implantable device to be carried by said implantable device for delivery at an implantation site; and (c) said hollow body having an opening and a sealing member disposed about said opening for preventing any significant leakage of said therapeutic substance out from said chamber cavity when said therapeutic substance is supplied.
Claim 2
Dependent Claim 132 words
A chamber which allows a user to medicate implantable devices, comprising: (a) a hollow body defining a chamber cavity, said chamber cavity is configured to removably encapsulate an implantable device, said implantable device can be delivered to an anatomical lumen of a mammal for the delivery of a therapeutic substance to said mammal; (b) an inlet disposed in said hollow body, said inlet allows a user to supply a therapeutic substance into said chamber cavity, wherein said therapeutic substance contacts said implantable device to be carried by said implantable device for delivery at an implantation site; and (c) said hollow body having an opening and a sealing member disposed about said opening for preventing any significant leakage of said therapeutic substance out from said chamber cavity when said therapeutic substance is supplied.
Claim 3
Dependent Claim 29 words
The chamber of claim 1 , additionally comprising an outlet disposed in said hollow body, said outlet allows said therapeutic substance to be discharged out of said chamber cavity.
Claim 4
Dependent Claim 88 words
A chamber which allows a user to medicate implantable devices, comprising: (a) a hollow body defining a chamber cavity, said chamber cavity is configured to encapsulate an implantable device; and (b) an inlet disposed in said hollow body, said inlet allows a user to supply a therapeutic substance into said chamber cavity, wherein said therapeutic substance contacts said implantable device, wherein said hollow body comprises a pair of opposing ends, each of said ends having an aperture and a sealing member disposed on a periphery of said aperture.
Claim 5
Dependent Claim 88 words
A chamber which allows a user to medicate implantable devices, comprising: (a) a hollow body defining a chamber cavity, said chamber cavity is configured to encapsulate an implantable device; and (b) an inlet disposed in said hollow body, said inlet allows a user to supply a therapeutic substance into said chamber cavity, wherein said therapeutic substance contacts said implantable device, wherein said hollow body comprises a pair of opposing ends, each of said ends having an aperture and a sealing member disposed on a periphery of said aperture.
Claim 6
Dependent Claim 13 words
The chamber of claim 1 , wherein said implantable device is a stent.
Claim 7
Dependent Claim 33 words
The chamber of claim 1 , wherein said hollow body comprises an upper chamber body and a lower chamber body, said chamber bodies configured to releasably secure together to form said chamber cavity.
Claim 8
Dependent Claim 27 words
The chamber of claim 1 , wherein said therapeutic substance is selected from a group of antineoplastic, antiplatelet, anticoagulant, fribrinolytic, antimitotic, thrombin inhibitor, antiinflammatory and antiproliferative substances.
Claim 9
Dependent Claim 21 words
The chamber of claim 1 , wherein said chamber is configured to removably encapsulate a balloon portion of a catheter assembly.
Claim 10
Dependent Claim 90 words
A chamber for exposing an implantable device positioned on a catheter assembly to a bioactive substance, comprising: a hollow body defining a chamber cavity, said chamber used for removeably securing on at least a portion of a catheter assembly to encapsulate an implantable device positioned on said catheter assembly, wherein said hollow body comprises an upper chamber body and a lower chamber body which can be releasably secured to said upper chamber body; and wherein a bioactive substance can be introduced into said chamber cavity to contact said implantable device.
Claim 11
Dependent Claim 90 words
A chamber for exposing an implantable device positioned on a catheter assembly to a bioactive substance, comprising: a hollow body defining a chamber cavity, said chamber used for removeably securing on at least a portion of a catheter assembly to encapsulate an implantable device positioned on said catheter assembly, wherein said hollow body comprises an upper chamber body and a lower chamber body which can be releasably secured to said upper chamber body; and wherein a bioactive substance can be introduced into said chamber cavity to contact said implantable device.
Claim 12
Dependent Claim 43 words
The chamber of claim 8 , additionally comprising an inlet disposed in said hollow body, said inlet used for communicating with a source of delivery of a bioactive substance for delivering said bioactive substance into said chamber cavity to contact said implantable device.
Claim 13
Dependent Claim 77 words
The chamber of claim 8 wherein said hollow body comprises a first end and an aperture located at said first end, the periphery of said aperture is in tight communication with a component of said catheter assembly when said chamber is secured on at least said portion of said catheter assembly so as to prevent any significant flow of said bioactive substance out from said chamber cavity when said bioactive substance is introduced into said chamber cavity.
Claim 14
Dependent Claim 28 words
The chamber of claim 8 , additionally comprising an outlet disposed in said hollow body for allowing said bioactive substance to be discharged out from said chamber cavity.
Claim 15
Dependent Claim 33 words
The chamber of claim 8 , wherein said implantable device is selected from a group of balloon expandable stents, self expandable stents, stents having a porous body, and stents having a polymeric coating.

References Cited (Backward Citations)

US5374257A Cited
US5785715A Cited
US5630830A Cited
US5833651A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2004-03-19 2004-09-18 2005-03-20 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2008-03-19 2008-09-18 2009-03-20 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2012-03-19 2012-09-18 2013-03-20 $7700.00 Window Closed / Lapsed

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