US6200564B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical compositions containing chondroitinase and uses therefor
Assignee: Select Therapeutics Inc
•
Filing: 1998-04-10
•
Granted: 2001-03-13
•
Expires: 2018-04-10
Abstract
Abstract Gastrointestinal mucus from patients suffering from cystic fibrosis has been found to contain large amounts of chondroitin sulfate polymer. This finding indicates that the enzyme chondroitinase is useful for preventing gastrointestinal mucus from accumulating in cystic fibrosis patients, and subjects suffering from other diseases or conditions characterized by excess mucus secretion.
Inventors
- 👤 J. Thomas Lamont
- 👤 K. Ramakrishnan Bhaskar
- 👤 Allan M. Green
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 07:33
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/43; A61K38/51; C; C12; C12Q; C12Q1/00; C12Q1/527; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/66; A61K48/00
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
47 words
A method for treating a subject having a disorder characterized by the accumulation of mucoid secretions, comprising administering to the subject a therapeutically effective amount of an agent that prevents chondroitin sulfate accumulation such that treatment of the subject occurs, wherein the agent is a chondroitinase enzyme.
Claim 2
Independent Claim
47 words
A method for treating a subject having a disorder characterized by the accumulation of mucoid secretions, comprising administering to the subject a therapeutically effective amount of an agent that prevents chondroitin sulfate accumulation such that treatment of the subject occurs, wherein the agent is a chondroitinase enzyme.
Claim 3
Dependent Claim
18 words
The method of claim 1 , wherein the agent prevents chondroitin sulfate accumulation by degrading the chondroitin sulfate.
Claim 4
Dependent Claim
13 words
The method of claim 2 , wherein the disorder is a pulmonary disorder.
Claim 5
Dependent Claim
13 words
The method of claim 3 , wherein the pulmonary disorder is cystic fibrosis.
Claim 6
Dependent Claim
13 words
The method of claim 2 , wherein the disorder is a pancreatobiliary disorder.
Claim 7
Dependent Claim
13 words
The method of claim 5 , wherein the pancreatobiliary disorder is biliary cirrhosis.
References Cited (Backward Citations)
US3502779A
Cited
SU742792A1
Cited
US4636195A
Cited
DD205332A1
Cited
EP0285439A2
Cited
US5112758A
Cited
WO1990006954A1
Cited
EP0613949A2
Cited
US5932481A
Cited
WO1995029256A1
Cited
WO1996030051A1
Cited
WO1997019351A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2004-03-12 | 2004-09-11 | 2005-03-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2008-03-12 | 2008-09-11 | 2009-03-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2012-03-12 | 2012-09-11 | 2013-03-13 | $7700.00 | Window Closed / Lapsed |