US6129697A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Thrombectomy and tissue removal device
Assignee: Bayer Medical Care Inc
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Filing: 1994-12-08
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Granted: 2000-10-10
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Expires: 2014-12-08
Abstract
Abstract A device for removing a thrombus or other tissue deposit from the cardiovascular system, or from a natural or synthetic tubule or cavity found in the human body of a patient without the need to surgically access the location of the thrombus or other tissue deposit via a cut-down or other surgical procedure. A flexible metal or high pressure plastic tube conveys an extremely high pressure stream of sterile saline or other physiologic solution to at least one orifice at the distal end of the catheter. At least one jet is directed at the opening of a large exhaust lumen or other target. The jet is responsible for providing a localized negative pressure which entrains tissue into the jet from break-up of the debris. This jet can also provide stagnation pressure in the exhaust lumen which drives the tissue or thrombotic debris out of the exhaust lumen. Operation of the device with tip pressure greater than 500 psi provides this device with the entrainment and exhaust characteristics which contribute to its effectiveness. The rate of exhaust of tissue debris is metered to ensure minimal local impact on the vasculature at the site of the thrombus deposit. A fluid metering means, such as a roller pump, controls the rate of exhaust such that it is in balance with the saline input or can be adjusted to be greater or less than the input. A positive displacement pump operating at steady or pulsatile flow provides the high pressure saline to the distal end of the catheter.
Inventors
- 👤 William J. Drasler
- 👤 Robert G. Dutcher
- 👤 Mark L. Jenson
- 👤 Joseph M. Thielen
- 👤 Emmanuil I. Protonotarios
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 15:17
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/32; A61B17/3203; A61B17/32037
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
317 words
A device for removing thrombus or other tissue from an occluded or obstructed biological or synthetic body vessel or from a body cavity comprising: a. a tubular member having a proximal end and a distal end, having a first passage and a second passage and a third passage extending along the length thereof, each passage with a proximal and distal end; b. a high pressure fluid source sealingly attached to said proximal end of said first passage which drives a flow of high pressure fluid into said proximal end of said first passage; c. said first passage comprising tubular means which carries the flow of high pressure fluid from said proximal end to said distal end, said distal end of said first passage having two or more orifices; d. said second passage comprising tubular means for carrying a flow of fluid and emulsified tissue from said distal end to said proximal end, said distal end of said second passage being open; e. fluid jets emanating from said orifices formed from the flow of of high pressure fluid carried by said first passage; f. said third passage comprising tubular means for providing communication between said proximal and distal ends of said tubular member; g. at least one of the fluid jets emanating from said distal end of said first passage impinges on said open distal end of said second passage ("impinging jets"), thereby providing stagnation pressure to drive the flow of emulsified tissue from said distal end of said second passage towards said proximal end of said second passage; h. at least one of the fluid jets are "outwardly-facing jets" directed substantially away from said tubular member rather than being directed to impinge on said open distal end of said second passage of said tubular member; and, i. said proximal end of said second passage provides removal of the emulsified tissue from the body vessel or body cavity.
Claim 2
Independent Claim
317 words
A device for removing thrombus or other tissue from an occluded or obstructed biological or synthetic body vessel or from a body cavity comprising: a. a tubular member having a proximal end and a distal end, having a first passage and a second passage and a third passage extending along the length thereof, each passage with a proximal and distal end; b. a high pressure fluid source sealingly attached to said proximal end of said first passage which drives a flow of high pressure fluid into said proximal end of said first passage; c. said first passage comprising tubular means which carries the flow of high pressure fluid from said proximal end to said distal end, said distal end of said first passage having two or more orifices; d. said second passage comprising tubular means for carrying a flow of fluid and emulsified tissue from said distal end to said proximal end, said distal end of said second passage being open; e. fluid jets emanating from said orifices formed from the flow of of high pressure fluid carried by said first passage; f. said third passage comprising tubular means for providing communication between said proximal and distal ends of said tubular member; g. at least one of the fluid jets emanating from said distal end of said first passage impinges on said open distal end of said second passage ("impinging jets"), thereby providing stagnation pressure to drive the flow of emulsified tissue from said distal end of said second passage towards said proximal end of said second passage; h. at least one of the fluid jets are "outwardly-facing jets" directed substantially away from said tubular member rather than being directed to impinge on said open distal end of said second passage of said tubular member; and, i. said proximal end of said second passage provides removal of the emulsified tissue from the body vessel or body cavity.
Claim 3
Independent Claim
320 words
A device for removing thrombus or other tissue from an occluded or obstructed biological or synthetic body vessel or from a body cavity comprising: a. a tubular member having a proximal end and a distal end, having a first passage and a second passage and a third passage extending along the length thereof, each passage with a proximal and distal end; b. a high pressure fluid source sealingly attached to said proximal end of said first passage which drives a flow of high pressure fluid into said proximal end of said first passage; c. said first passage comprising tubular means which carries the flow of high pressure fluid from said proximal end to said distal end, said distal end of said first passage having two or more orifices; d. said second passage comprising tubular means for carrying a flow of fluid and emulsified tissue from said distal end to said proximal end, the distal end of said second passage being open; e. fluid jets emanating from said orifices formed from the flow of high pressure fluid carried by said first passage; f. said third passage comprising tubular means for providing communication between said proximal and distal ends of the tubular member; g. at least one of the fluid jets emanating from said distal end of said first passage impinges on said open distal end of said second passage ("impinging jets"), the said high pressure fluid in the said first passage being under high pressure greater than approximately 500 psi, providing sufficient energy in the jets to cut or emulsify harder tissue; h. at least one of the fluid jets are "outwardly-facing jets" directed substantially away from said tubular member rather than being directed to impinge on said open distal end of said second passage of said tubular member; and, i. said proximal end of said second passage provides removal of the emulsified tissue from the body vessel or body cavity.
Claim 4
Independent Claim
320 words
A device for removing thrombus or other tissue from an occluded or obstructed biological or synthetic body vessel or from a body cavity comprising: a. a tubular member having a proximal end and a distal end, having a first passage and a second passage and a third passage extending along the length thereof, each passage with a proximal and distal end; b. a high pressure fluid source sealingly attached to said proximal end of said first passage which drives a flow of high pressure fluid into said proximal end of said first passage; c. said first passage comprising tubular means which carries the flow of high pressure fluid from said proximal end to said distal end, said distal end of said first passage having two or more orifices; d. said second passage comprising tubular means for carrying a flow of fluid and emulsified tissue from said distal end to said proximal end, the distal end of said second passage being open; e. fluid jets emanating from said orifices formed from the flow of high pressure fluid carried by said first passage; f. said third passage comprising tubular means for providing communication between said proximal and distal ends of the tubular member; g. at least one of the fluid jets emanating from said distal end of said first passage impinges on said open distal end of said second passage ("impinging jets"), the said high pressure fluid in the said first passage being under high pressure greater than approximately 500 psi, providing sufficient energy in the jets to cut or emulsify harder tissue; h. at least one of the fluid jets are "outwardly-facing jets" directed substantially away from said tubular member rather than being directed to impinge on said open distal end of said second passage of said tubular member; and, i. said proximal end of said second passage provides removal of the emulsified tissue from the body vessel or body cavity.
Claim 5
Dependent Claim
19 words
The device of claim 1 or 2 wherein the outwardly-facing jet(s) have lower fluid velocity than the impinging jets.
Claim 6
Dependent Claim
41 words
The device of claim 3 further comprising a fluid resistance narrowing found in said distal end of said first passage which by virtue of narrowed region(s) creates pressure losses and thereby provides for said lower fluid velocity of said outwardly-facing jet(s).
Claim 7
Dependent Claim
26 words
The device of claim 3 as wherein any or a combination of fluid resistance narrowing(s) dissipate and distribute energy and provide for the lower fluid velocity.
Claim 8
Independent Claim
286 words
A device for removing thrombus or other tissue from an occluded or obstructed biological or synthetic body vessel or from a body cavity comprising; a. a tubular member having a proximal end and a distal end, having a first passage and a second passage and a third passage extending along the length thereof, each passage with a proximal and distal end; b. a high pressure fluid source sealinqly attached to said proximal end of said first passage which drives a flow of high pressure fluid into said proximal end of said first passage; c. said first passage comprising tubular means which carries the flow of high pressure fluid from said proximal end to said distal end, said distal end of said first passage having two or more orifices; d. said second passage comprising tubular means for carrying a flow of fluid and emulsified tissue from said distal end to said proximal end, said distal end of said second passage being open; e. fluid jets emanating from said orifices formed from the flow of of high pressure fluid carried by said first passage; f. said third passage comprising tubular means for providing communication between said proximal and distal ends of said tubular member; g. at least one of the fluid jets emanating from said distal end of said first passage impinges on said open distal end of said second passage ("impinging jets"), thereby providing a low pressure region which tends to bring the tissue towards the jet(s); h. at least one of the fluid jets are "outwardly-facing jets" directed substantially away from said tubular member; and, i. said proximal end of said second passage provides removal of the emulsified tissue from the body vessel or body cavity.
Claim 9
Independent Claim
286 words
A device for removing thrombus or other tissue from an occluded or obstructed biological or synthetic body vessel or from a body cavity comprising; a. a tubular member having a proximal end and a distal end, having a first passage and a second passage and a third passage extending along the length thereof, each passage with a proximal and distal end; b. a high pressure fluid source sealinqly attached to said proximal end of said first passage which drives a flow of high pressure fluid into said proximal end of said first passage; c. said first passage comprising tubular means which carries the flow of high pressure fluid from said proximal end to said distal end, said distal end of said first passage having two or more orifices; d. said second passage comprising tubular means for carrying a flow of fluid and emulsified tissue from said distal end to said proximal end, said distal end of said second passage being open; e. fluid jets emanating from said orifices formed from the flow of of high pressure fluid carried by said first passage; f. said third passage comprising tubular means for providing communication between said proximal and distal ends of said tubular member; g. at least one of the fluid jets emanating from said distal end of said first passage impinges on said open distal end of said second passage ("impinging jets"), thereby providing a low pressure region which tends to bring the tissue towards the jet(s); h. at least one of the fluid jets are "outwardly-facing jets" directed substantially away from said tubular member; and, i. said proximal end of said second passage provides removal of the emulsified tissue from the body vessel or body cavity.
Claim 10
Dependent Claim
56 words
The device of claim 1, 6 or 2 further comprising a metering means which is connected to said proximal end of said second passage to control the flow of fluid and emulsified tissue in said second passage at a controlled rate of flow less than the rate of flow which would result without said metering means.
Claim 11
Dependent Claim
14 words
The device of claim 7 wherein said metering means consists of a roller pump.
Claim 12
Dependent Claim
43 words
The device of claim 7 wherein said metering means controls the rate of flow of fluid and emulsified tissue in said second passage at a rate of flow controlled relative to the rate of flow of high pressure fluid in the first passage.
Claim 13
Dependent Claim
56 words
The device of claim 1, 6 or 2 further comprising a suction means which is connected to said proximal end of said second passage to control the flow of fluid and emulsified tissue in said second passage at a controlled rate of flow greater than the rate of flow which would result without said suction means.
Claim 14
Dependent Claim
14 words
The device of claim 10 wherein said suction means consists of a roller pump.
Claim 15
Dependent Claim
43 words
The device of claim 10 wherein said suction means controls the rate of flow of fluid and emulsified tissue in said second passage at a rate of flow controlled relative to the rate of flow of high pressure fluid in the first passage.
Claim 16
Dependent Claim
19 words
The device of claim 1, 6 or 2 wherein said high pressure fluid source is a positive-displacement piston pump.
Claim 17
Dependent Claim
21 words
The device of claim 1, 6 or 2 wherein therapeutic material is delivered through said first passage of said tubular member.
Claim 18
Dependent Claim
37 words
The device of claim 14 wherein the high pressure fluid carried in said first passage contains the therapeutic material; thereby the fluid jets emanating from said distal portion of said first passage also contain the therapeutic material.
Claim 19
Dependent Claim
21 words
The device of claim 1, 6 or 2 wherein diagnostic medium is delivered through said second passage of said tubular member.
Claim 20
Dependent Claim
37 words
The device of claim 16 wherein the high pressure fluid carried in said first passage contains the diagnostic medium; thereby the fluid jets emanating from said distal portion of said first passage also contain the diagnostic medium.
Claim 21
Dependent Claim
23 words
The device of claim 1, 6 or 2 wherein said second passage of said tubular member also provides passage for a catheter device.
Claim 22
Dependent Claim
30 words
The device of claim 1, 6 or 2 wherein said third passage provides communication between said proximal and distal ends of said tubular member for, passage of a guidewire device.
Claim 23
Dependent Claim
43 words
The device of claim 1, 6 or 2 wherein said distal end of said first passage is formed into an arcuate shape extending beyond said second passage to direct one or more of the jets onto said distal end of said second passage.
Claim 24
Dependent Claim
75 words
The device of claim 20 wherein the fluid jets emanate from various points along said arcuate-shaped portion of said first passage; when a guidewire device is in position near said distal end of said first passage and extends through said arcuate-shaped first passage, the jets are therefore oriented at various points around the guidewire device thereby decreasing any effect that the guidewire device may have in shielding the tissue from the effects of the jets.
Claim 25
Dependent Claim
46 words
The device of claim 1, 6 or 2 wherein said distal end of said first passage is formed into a toroidal shape which is oriented in a plane perpendicular to the axis of said tubular member and distal to said distal end of said second passage.
Claim 26
Dependent Claim
80 words
The device of claim 22 wherein the fluid jets emanate from various points along the toroidal-shaped portion of said first passage; when a guidewire device is in position through said distal end of said second passage and extends further through said toroidal-shaped portion of said first passage. the jets are therefore oriented at various points circumferentially around the guidewire device thereby decreasing any effect that the guidewire device may have in shielding the tissue from the effects of the jets.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-10-10 | 2004-04-10 | 2004-10-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-10-10 | 2008-04-10 | 2008-10-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-10-10 | 2012-04-10 | 2012-10-10 | $7700.00 | Window Closed / Lapsed |