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US6071302A Expired / Lapsed US ⏱️ 0.0 years remaining

Phototherapeutic apparatus for wide-angle diffusion

Assignee: Cardiofocus Inc
•
Filing: 1997-12-31
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Granted: 2000-06-06
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Expires: 2017-12-31
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Abstract

Abstract A low-profile, diffusive tip apparatus adapted for insertion into a body to deliver phototherapeutic radiation by scattering light in a substantially omnidirectional pattern includes a light-transmissive housing that is adapted for mounting, at its proximal end, onto a fiber optic cable, and, at its distal end, the housing defines or is joined to a light-transmissive cap having a diameter which is not substantially greater than the diameter of the optical fiber. The light transmissive cap region encloses a chamber or reservoir filled with an optically scattering medium and, preferably, hemispherical in shape with a radius of curvature substantially equal to the radius of the housing.

Inventors

  • 👤 Edward L. Sinofsky
  • 👤 Lincoln S. Baxter

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 19:21
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/06; A61N5/0601; A61B; A61B18/00; A61B18/18; A61B18/20; A61B18/22; A61B2018/2255; A61B2018/2261

Claims Analysis

Total Claims: 20
Claim 1
Independent Claim 144 words
A low-profile diffusive tip apparatus for diffusion of light propagating through an optical fiber, the diffusive tip apparatus comprising: a housing extending along a longitudinal axis, the housing having an open proximal end adapted to receive a light-transmitting optical fiber and a closed distal end forming a chamber for containing a scattering material, the distal end having a generally hemispherical shape, at least a portion of the distal end being transparent to light at a desired wavelength for diffusion; and a light scattering material contained within the chamber so as to conform to the hemisperical shape of the housing distal end, the scattering material having a predefined concentration of scattering particles and the shape of the distal end having a predetermined shape, the predefined concentration and the predetermined shape cooperating to provide substantially uniform irradiation over a spherical angle of at least 2π steradians.
Claim 2
Dependent Claim 144 words
A low-profile diffusive tip apparatus for diffusion of light propagating through an optical fiber, the diffusive tip apparatus comprising: a housing extending along a longitudinal axis, the housing having an open proximal end adapted to receive a light-transmitting optical fiber and a closed distal end forming a chamber for containing a scattering material, the distal end having a generally hemispherical shape, at least a portion of the distal end being transparent to light at a desired wavelength for diffusion; and a light scattering material contained within the chamber so as to conform to the hemisperical shape of the housing distal end, the scattering material having a predefined concentration of scattering particles and the shape of the distal end having a predetermined shape, the predefined concentration and the predetermined shape cooperating to provide substantially uniform irradiation over a spherical angle of at least 2π steradians.
Claim 3
Dependent Claim 30 words
The diffusive tip apparatus of claim 1 wherein the housing is tubular and the proximal end further comprises a sleeve portion adapted to slide over the end of a fiber.
Claim 4
Dependent Claim 30 words
The diffusive tip apparatus of claim 2, wherein the sleeve portion is further adapted to slide over the end of the fiber which has been stripped of its outer buffer.
Claim 5
Dependent Claim 31 words
The diffusive tip apparatus of claim 2, wherein the housing further comprises a polymeric material which can be bonded to the fiber by application of heat following mounting upon the fiber.
Claim 6
Dependent Claim 25 words
The diffusive tip apparatus of claim 1 wherein the light scattering material comprises a multiplicity of light scattering particles suspended in an optically transmissive medium.
Claim 7
Dependent Claim 29 words
The diffusive tip apparatus of claim 5, wherein the optically transmissive medium is selected from a group consisting of silicone, epoxy, acetic acid, deuterium oxide, water and combinations thereof.
Claim 8
Dependent Claim 24 words
The diffusive tip apparatus of claim 5, wherein the scattering particles are selected from a group consisting of silica, alumina, titania and combinations thereof.
Claim 9
Dependent Claim 17 words
The diffusive tip apparatus of claim 5, wherein the optically transmissive medium is a heavy water solution.
Claim 10
Dependent Claim 17 words
The diffusive tip apparatus of claim 5, wherein the scattering particles are distributed uniformly within the cavity.
Claim 11
Dependent Claim 15 words
The diffusive tip apparatus of claim 1 wherein the housing further comprises a fluorocarbon material.
Claim 12
Dependent Claim 15 words
The diffusive tip apparatus of claim 10, wherein the housing further comprises a polyperfluoroethylene-propylene copolymer.
Claim 13
Dependent Claim 19 words
The diffusive tip apparatus of claim 10, wherein the housing further comprises a polytetrafluoroethylene polymer with perfluoroalkoxy side chains.
Claim 14
Dependent Claim 14 words
The diffusive tip apparatus of claim 10, wherein the housing further comprises a polytetrafluoroethylene.
Claim 15
Dependent Claim 69 words
The diffusive tip apparatus of claim 1 wherein the scattering material and defined shape of the housing distal end cooperate to yield a pattern of light diffusion over a spherical angle of at least 2π steradians in which the intensity measured at any point equidistant from the diffusive top apparatus does not vary more than ±30 percent from the average intensity measured at the same distance from the diffuser.
Claim 16
Dependent Claim 26 words
The diffusive tip apparatus of claim 1 wherein the distal end of housing is further adapted to provide a substantially flush joint with an optical fiber.
Claim 17
Dependent Claim 143 words
A fiber optic instrument for performing phototherapy comprising: a light transmissive fiber; a low-profile diffusive tip apparatus for diffusion of light propagating through the light transmissive fiber, the diffusive tip apparatus comprising a housing extending along a longitudinal axis, the housing having an open proximal end adapted to receive the light-transmitting optical fiber and a closed distal end forming a chamber for containing a scattering material, the distal end having a substantially hemispherical shape, at least a portion of the distal end being transparent to light at a desired wavelength for diffusion; and a light scattering material contained within the chamber and conforming to the hemispherical distal end of the housing, the scattering material having a predefined concentration of scattering particles, the predefined concentration and the hemispherical shape cooperating to provide substantially uniform irradiation over a spherical angle of at least 2π steradians.
Claim 18
Dependent Claim 143 words
A fiber optic instrument for performing phototherapy comprising: a light transmissive fiber; a low-profile diffusive tip apparatus for diffusion of light propagating through the light transmissive fiber, the diffusive tip apparatus comprising a housing extending along a longitudinal axis, the housing having an open proximal end adapted to receive the light-transmitting optical fiber and a closed distal end forming a chamber for containing a scattering material, the distal end having a substantially hemispherical shape, at least a portion of the distal end being transparent to light at a desired wavelength for diffusion; and a light scattering material contained within the chamber and conforming to the hemispherical distal end of the housing, the scattering material having a predefined concentration of scattering particles, the predefined concentration and the hemispherical shape cooperating to provide substantially uniform irradiation over a spherical angle of at least 2π steradians.
Claim 19
Independent Claim 187 words
A method of performing phototherapy within a patient, said method comprising the steps of: introducing a fiber optic instrument having an optical fiber and a low-profile diffusive tip apparatus for diffusion of light propagating through the optical fiber, the diffusive tip apparatus comprising a housing extending along a longitudinal axis, the housing having an open proximal end adapted to receive a light-transmitting optical fiber and a closed distal end forming a hemispherical chamber for containing a scattering material, at least a portion of the distal end being transparent to light at a desired wavelength for diffusion; and a light scattering material contained within the and conforming to the hemispherical shape of the housing distal end, the scattering material having a sufficient concentration of scatterer particles and the hemispherical shape of the distal tip providing substantially uniform irradiation over a spherical angle of at least 2π steradians; positioning the diffusive tip apparatus at a target treatment region within the patient; and activating a light source coupled to the fiber such that light propagates down the fiber and is diffused into the target treatment region to provide phototherapeutic radiation.
Claim 20
Independent Claim 187 words
A method of performing phototherapy within a patient, said method comprising the steps of: introducing a fiber optic instrument having an optical fiber and a low-profile diffusive tip apparatus for diffusion of light propagating through the optical fiber, the diffusive tip apparatus comprising a housing extending along a longitudinal axis, the housing having an open proximal end adapted to receive a light-transmitting optical fiber and a closed distal end forming a hemispherical chamber for containing a scattering material, at least a portion of the distal end being transparent to light at a desired wavelength for diffusion; and a light scattering material contained within the and conforming to the hemispherical shape of the housing distal end, the scattering material having a sufficient concentration of scatterer particles and the hemispherical shape of the distal tip providing substantially uniform irradiation over a spherical angle of at least 2π steradians; positioning the diffusive tip apparatus at a target treatment region within the patient; and activating a light source coupled to the fiber such that light propagates down the fiber and is diffused into the target treatment region to provide phototherapeutic radiation.

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2003-06-06 2003-12-06 2004-06-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2007-06-06 2007-12-06 2008-06-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2011-06-06 2011-12-06 2012-06-06 $7700.00 Window Closed / Lapsed

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