US6050992A
Expired / Lapsed
US
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Apparatus and method for treating tissue with multiple electrodes
Assignee: Boston Scientific Scimed Inc
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Filing: 1997-05-19
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Granted: 2000-04-18
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Expires: 2017-05-19
Abstract
Abstract A probe system for volumetric tissue heating and ablation comprises a cannula having a multiple electrode component reciprocatably mounted therein. Individual electrodes within the array have spring memory so that they assume a radially outward, arcuate configuration as they are advanced distally from the cannula. Preferably, the electrodes fully evert as they are advanced from the cannula. Prior to deployment, the electrodes are constrained within a lumen of the cannula. The electrodes are maintained with a uniform circumferential spacing by confining them within an annular envelope defined by a core member within the cannula lumen, by providing electrodes having asymmetric cross-sectional geometries, and/or by nesting the electrodes closely together. Optionally, a cutting current may be applied to the electrodes as they are advanced.
Inventors
- 👤 Colin J. Nichols
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 14:00
CPC Classifications
A; A61; A61B; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/1477
Claims Analysis
Total Claims: 72
Claim 1
Independent Claim
139 words
A probe system for penetrating a plurality of electrodes into tissue, said probe system comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end, a core disposed coaxially within the cannula lumen, said core having a cylindrical outer surface which together with an inner surface of the cannula lumen defines an annular envelope; and a plurality of resilient electrodes disposed in the annular envelope wherein at least a portion of the electrodes are mechanically coupled to the core to reciprocate between a proximally retracted position wherein all electrodes are radially constrained within the lumen and a distally extended position wherein all electrodes deploy radially outwardly, said plurality including at least three electrodes, whereby the envelope maintains substantially equal circumferential spacing between adjacent electrodes when retracted in the cannula lumen.
Claim 2
Dependent Claim
139 words
A probe system for penetrating a plurality of electrodes into tissue, said probe system comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end, a core disposed coaxially within the cannula lumen, said core having a cylindrical outer surface which together with an inner surface of the cannula lumen defines an annular envelope; and a plurality of resilient electrodes disposed in the annular envelope wherein at least a portion of the electrodes are mechanically coupled to the core to reciprocate between a proximally retracted position wherein all electrodes are radially constrained within the lumen and a distally extended position wherein all electrodes deploy radially outwardly, said plurality including at least three electrodes, whereby the envelope maintains substantially equal circumferential spacing between adjacent electrodes when retracted in the cannula lumen.
Claim 3
Dependent Claim
20 words
A probe system as in claim 1, wherein the core has a sharpened distal end to facilitate penetration into tissue.
Claim 4
Dependent Claim
16 words
A probe system as in claim 1, wherein the core is electrically coupled to the electrodes.
Claim 5
Dependent Claim
16 words
A probe system as in claim 1, wherein the core is electrically isolated from the electrodes.
Claim 6
Dependent Claim
37 words
A probe system as in claim 1, wherein at least one of the outer cylindrical surface of the core and the inner surface of the cannula lumen has channels formed therein for receiving and aligning the electrodes.
Claim 7
Dependent Claim
35 words
A probe system as in claim 1, wherein the annular envelope has a width in a radial direction which is less than or equal to a distance twice that of the thickness of an electrode.
Claim 8
Dependent Claim
38 words
A probe system as in claim 1, wherein at least some of the electrodes are shaped so that they assume an outwardly everted configuration as they are extended distally into tissue from the distal end of the cannula.
Claim 9
Dependent Claim
36 words
A probe system as in claim 1, further comprising a stylet reciprocatably received in the cannula lumen, wherein the stylet may be used for initially positioning the cannula in tissue and thereafter exchanged with the electrodes.
Claim 10
Dependent Claim
35 words
A probe system as in claim 1, wherein the cannula has a length in the range from 5 cm to 30 cm and an outer diameter in the range from 1 mm to 5 mm.
Claim 11
Dependent Claim
31 words
A probe system as in claim 1, wherein the electrodes deploy outwardly to a radius in the range from 0.5 cm to 3 cm when fully distally extended from the cannula.
Claim 12
Dependent Claim
15 words
A probe system as in claim 1, wherein the plurality includes at least five electrodes.
Claim 13
Dependent Claim
15 words
A probe system as in claim 1, wherein the plurality includes at least eight electrodes.
Claim 14
Dependent Claim
15 words
A probe system as in claim 1, wherein the plurality includes at least ten electrodes.
Claim 15
Dependent Claim
120 words
A probe system for penetrating a plurality of electrodes into tissue, said probe system comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end; and a plurality of resilient electrodes, at least a portion having asymmetric cross-sections with a major dimension aligned circumferentially and a minor dimension aligned radially, disposed in the cannula lumen to reciprocate between a proximally retracted position wherein all electrodes are radially constrained within the lumen and a distally extended position wherein all electrodes deploy radially outwardly, said plurality including at least three electrodes, whereby the shape and alignment of the electrodes maintains substantially equal circumferential spacing between adjacent electrodes when retracted in the cannula lumen.
Claim 16
Dependent Claim
120 words
A probe system for penetrating a plurality of electrodes into tissue, said probe system comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end; and a plurality of resilient electrodes, at least a portion having asymmetric cross-sections with a major dimension aligned circumferentially and a minor dimension aligned radially, disposed in the cannula lumen to reciprocate between a proximally retracted position wherein all electrodes are radially constrained within the lumen and a distally extended position wherein all electrodes deploy radially outwardly, said plurality including at least three electrodes, whereby the shape and alignment of the electrodes maintains substantially equal circumferential spacing between adjacent electrodes when retracted in the cannula lumen.
Claim 17
Dependent Claim
20 words
A probe system as in claim 14, wherein the major dimension is at least 50% larger than the minor dimension.
Claim 18
Dependent Claim
14 words
A probe system as in claim 15, wherein the electrodes have a rectangular cross-section.
Claim 19
Dependent Claim
22 words
A probe system as in claim 14, wherein the electrodes are nested together in a close packed configuration within an annular ring.
Claim 20
Dependent Claim
38 words
A probe system as in claim 14, wherein at least some of the electrodes are shaped so that they assume an outwardly everted configuration as they are extended distally into tissue from the distal end of the cannula.
Claim 21
Dependent Claim
36 words
A probe system as in claim 14, further comprising a stylet reciprocatably received in the cannula lumen, wherein the stylet may be used for initially positioning the cannula in tissue and thereafter exchanged with the electrodes.
Claim 22
Dependent Claim
35 words
A probe system as in claim 14, wherein the cannula has a length in the range from 5 cm to 30 cm and an outer diameter in the range from 1 mm to 5 mm.
Claim 23
Dependent Claim
31 words
A probe system as in claim 14, wherein the electrodes deploy outwardly to a radius in the range from 0.5 cm to 3 cm when fully distally extended from the cannula.
Claim 24
Dependent Claim
15 words
A probe system as in claim 14, wherein the plurality includes at least five electrodes.
Claim 25
Dependent Claim
15 words
A probe system as in claim 14, wherein the plurality includes at least eight electrodes.
Claim 26
Dependent Claim
15 words
A probe system as in claim 14, wherein the plurality includes at least ten electrodes.
Claim 27
Dependent Claim
105 words
A probe system comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end, a cylindrical core disposed coaxially within the cannula lumen to define an annular envelope; and a plurality of resilient electrodes disposed in the annular envelope to reciprocate between a proximally retracted position wherein all electrodes are radially constrained within the envelope and a distally extended position wherein all electrodes deploy radially outwardly, at least a portion of said electrodes having asymmetric cross-sections with a major dimension aligned circumferentially within the annular envelope and a minor dimension aligned radially within the annular envelope.
Claim 28
Dependent Claim
105 words
A probe system comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end, a cylindrical core disposed coaxially within the cannula lumen to define an annular envelope; and a plurality of resilient electrodes disposed in the annular envelope to reciprocate between a proximally retracted position wherein all electrodes are radially constrained within the envelope and a distally extended position wherein all electrodes deploy radially outwardly, at least a portion of said electrodes having asymmetric cross-sections with a major dimension aligned circumferentially within the annular envelope and a minor dimension aligned radially within the annular envelope.
Claim 29
Dependent Claim
19 words
A probe system as in claim 25, wherein the core is mechanically coupled to and reciprocates with the electrodes.
Claim 30
Dependent Claim
20 words
A probe system as in claim 26, wherein the core has a sharpened distal end to facilitate penetration into tissue.
Claim 31
Dependent Claim
16 words
A probe system as in claim 25, wherein the core is electrically coupled to the electrodes.
Claim 32
Dependent Claim
16 words
A probe system as in claim 25, wherein the core is electrically isolated from the electrodes.
Claim 33
Dependent Claim
36 words
A probe system as in claim 25, wherein the core is mechanically coupled to the cannula so that the electrodes translate past the surface of the core as the electrodes are advanced distally from the cannula.
Claim 34
Dependent Claim
37 words
A probe system as in claim 25, wherein at least one of the outer cylindrical surface of the core and the inner surface of the cannula lumen has channels formed therein for receiving and aligning the electrodes.
Claim 35
Dependent Claim
35 words
A probe system as in claim 25, wherein the annular envelope has a width in a radial direction which is less than or equal to a distance twice that of the thickness of an electrode.
Claim 36
Dependent Claim
24 words
A probe system as in claim 25, wherein the major dimension of the electrode cross-section is at least 50% larger than the minor dimension.
Claim 37
Dependent Claim
16 words
A probe system as in claim 33, wherein the electrodes have a rectangular or trapezoidal cross-section.
Claim 38
Dependent Claim
38 words
A probe system as in claim 25, wherein at least some of the electrodes are shaped so that they assume an outwardly everted configuration as they are extended distally into tissue from the distal end of the cannula.
Claim 39
Dependent Claim
36 words
A probe system as in claim 25, further comprising a stylet reciprocatably received in the cannula lumen, wherein the stylet may be used for initially positioning the cannula in tissue and thereafter exchanged with the electrodes.
Claim 40
Dependent Claim
35 words
A probe system as in claim 25, wherein the cannula has a length in the range from 5 cm to 30 cm and an outer diameter in the range from 1 mm to 5 mm.
Claim 41
Dependent Claim
31 words
A probe system as in claim 25, wherein the electrodes deploy outwardly to a radius in the range from 0.5 cm to 3 cm when fully distally extended from the cannula.
Claim 42
Dependent Claim
15 words
A probe system as in claim 25, wherein the plurality includes at least three electrodes.
Claim 43
Dependent Claim
15 words
A probe system as in claim 25, wherein the plurality includes at least five electrodes.
Claim 44
Dependent Claim
15 words
A probe system as in claim 25, wherein the plurality includes at least eight electrodes.
Claim 45
Dependent Claim
15 words
A probe system as in claim 25, wherein the plurality includes at least ten electrodes.
Claim 46
Dependent Claim
58 words
A probe system comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end; and at least four electrodes reciprocatably disposed within the lumen of the cannula, wherein the electrodes are nested within an annulus within the cannula lumen when retracted therein, each said electrode having an asymmetric cross-section.
Claim 47
Dependent Claim
58 words
A probe system comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end; and at least four electrodes reciprocatably disposed within the lumen of the cannula, wherein the electrodes are nested within an annulus within the cannula lumen when retracted therein, each said electrode having an asymmetric cross-section.
Claim 48
Dependent Claim
12 words
A probe system as in claim 43, including at least eight electrodes.
Claim 49
Dependent Claim
37 words
A probe system as in claim 43, wherein the annulus is constrained to have a width in a radial direction which is less than or equal to a distance twice that of the thickness of an electrode.
Claim 50
Dependent Claim
15 words
A probe system as in claim 43, wherein the asymmetric cross-sections are rectangular or trapezoidal.
Claim 51
Dependent Claim
38 words
A probe system as in claim 43, wherein at least some of the electrodes are shaped so that they assume an outwardly everted configuration as they are extended distally into tissue from the distal end of the cannula.
Claim 52
Dependent Claim
35 words
A probe system as in claim 43, wherein the cannula has a length in the range from 5 cm to 30 cm and an outer diameter in the range from 1 mm to 5 mm.
Claim 53
Dependent Claim
31 words
A probe system as in claim 43, wherein the electrodes deploy outwardly to a radius in the range from 0.5 cm to 3 cm when fully distally extended from the cannula.
Claim 54
Independent Claim
99 words
A method for delivering current to a target region within solid tissue comprising: constraining a plurality of at least three electrodes within a cannula, wherein at least a portion of the electrodes have an asymmetrical cross-section and a distal tip arranged in a pattern whereby the distal tips are substantially equally spaced-apart within an annular region near a distal end of the cannula, advancing the electrodes distally from the cannula into tissue at the target region, wherein the electrodes deploy radially outwardly in a symmetric pattern into the tissue; and applying electrical current to the tissue through the electrodes.
Claim 55
Independent Claim
99 words
A method for delivering current to a target region within solid tissue comprising: constraining a plurality of at least three electrodes within a cannula, wherein at least a portion of the electrodes have an asymmetrical cross-section and a distal tip arranged in a pattern whereby the distal tips are substantially equally spaced-apart within an annular region near a distal end of the cannula, advancing the electrodes distally from the cannula into tissue at the target region, wherein the electrodes deploy radially outwardly in a symmetric pattern into the tissue; and applying electrical current to the tissue through the electrodes.
Claim 56
Dependent Claim
67 words
A method as in claim 49, wherein the electrode distal tips are disposed in an annular region defined between an outer cylindrical surface of a core member disposed in the cannula and an inner cylindrical surface of a lumen of the cannula, wherein the distance between said outer cylindrical surface and said inner cylindrical surface is no more than twice that of the thickness of an electrode.
Claim 57
Dependent Claim
34 words
A method in claim 50, wherein a cannula lumen reciprocatably receives a core, said core having a cylindrical outer surface which together with the inner surface of the cannula lumen defines the annular region.
Claim 58
Dependent Claim
17 words
A method as in claim 52, wherein the core advances into the tissue together with the electrodes.
Claim 59
Dependent Claim
20 words
A method as in claim 52, wherein the electrodes advance past the core which remains immobile relative to the cannula.
Claim 60
Dependent Claim
52 words
A method as in claim 50, wherein the asymmetric cross-sections have a major dimension aligned circumferentially to maintain axial alignment of the electrodes and minor dimension aligned radially, where the electrodes are shaped to bend about an axis parallel to the minor dimension as the electrodes are advanced distally from the cannula.
Claim 61
Dependent Claim
28 words
A method as in claim 50, wherein the tips of the electrodes are nested within an annulus near the distal end of the cannula lumen prior to advancement.
Claim 62
Dependent Claim
13 words
A method as in claim 50, wherein the current is radio frequency current.
Claim 63
Dependent Claim
31 words
A method as in claim 50, wherein the electrodes are attached to one pole of a current source and a dispersive electrode is attached to another pole of the current source.
Claim 64
Dependent Claim
41 words
A method as in claim 50, wherein some of the electrodes are attached to one pole of a current source and others of the electrodes are attached to another pole of the current source to deliver current in a bipolar manner.
Claim 65
Independent Claim
55 words
A method for deploying electrodes in tissue, said method comprising: providing a plurality of at least three asymmetric electrodes constrained within a cannula; and advancing each of the electrodes distally from the cannula into tissue, wherein spacing between adjacent electrodes is maintained within ±20% of the average distance between electrodes as the electrodes are advanced.
Claim 66
Independent Claim
55 words
A method for deploying electrodes in tissue, said method comprising: providing a plurality of at least three asymmetric electrodes constrained within a cannula; and advancing each of the electrodes distally from the cannula into tissue, wherein spacing between adjacent electrodes is maintained within ±20% of the average distance between electrodes as the electrodes are advanced.
Claim 67
Dependent Claim
18 words
A method as in claim 60, wherein the spacing is maintained to within ±10% of the average distance.
Claim 68
Dependent Claim
18 words
A method as in claim 60, wherein the spacing is maintained to within ±5% of the average distance.
Claim 69
Dependent Claim
19 words
A method as in claim 60, wherein the spacing is further maintained by a central core within the cannula.
Claim 70
Dependent Claim
20 words
A method as in claim 60, wherein the spacing is further maintained by providing the electrodes in a nested configuration.
Claim 71
Dependent Claim
20 words
A method as in claim 60, further comprising applying a cutting RF current to the electrodes as they are advanced.
Claim 72
Dependent Claim
20 words
A method as in claim 65, further comprising applying an ablating RF current to the electrodes after they are advanced.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-04-18 | 2003-10-18 | 2004-04-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-04-18 | 2007-10-18 | 2008-04-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-04-18 | 2011-10-18 | 2012-04-18 | $7700.00 | Window Closed / Lapsed |