US6025474A
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Isolated nucleic acid molecules coding for tumor rejection antigen precursor mage-3 and uses thereof
Assignee: Ludwig Cancer Research
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Filing: 1997-11-12
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Granted: 2000-02-15
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Expires: 2017-11-12
Abstract
Abstract The invention relates to nucleic acid molecules which code for the tumor rejection antigen precursor MAGE-3. Also disclosed are vectors, cell lines, and so forth, which utilize the nucleic acid molecule, and optionally, molecules coding for human leukocyte antigen HLA-A1. Uses of these materials in therapeutic and diagnostic contexts are also a part of the invention.
Inventors
- 👤 Benoit Van den Eynde
- 👤 Pierre van den Bruggen
- 👤 Thierry Boon-Falleur
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 03:40
CPC Classifications
C; C07; C07K; C07K16/00; C07K16/18; C07K16/28; C07K16/30; A; A61; A61P; A61P35/00; C07K14/00; C07K14/435; C07K14/46; C07K14/47; C07K14/4701; C07K14/4748; A61K; A61K38/00; A61K39/00
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
44 words
An isolated tumor rejection antigen precursor protein, the amino acid sequence of which comprises the amino acid sequence of a protein encoded by a nucleic acid molecule consisting of the nucleotide sequence set forth in SEQ. ID NO: 11 or SEQ ID. NO: 12.
Claim 2
Dependent Claim
44 words
An isolated tumor rejection antigen precursor protein, the amino acid sequence of which comprises the amino acid sequence of a protein encoded by a nucleic acid molecule consisting of the nucleotide sequence set forth in SEQ. ID NO: 11 or SEQ ID. NO: 12.
Claim 3
Dependent Claim
16 words
A composition comprising the isolated tumor rejection antigen precursor protein of claim 1, and an adjuvant.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-02-14 | 2003-08-16 | 2004-02-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-02-14 | 2007-08-16 | 2008-02-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-02-14 | 2011-08-16 | 2012-02-15 | $7700.00 | Window Closed / Lapsed |