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US6001088A Expired / Lapsed US ⏱️ 0.0 years remaining

Iontophoresis method and apparatus

Assignee: University of Queensland
•
Filing: 1995-12-04
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Granted: 1999-12-14
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Expires: 2015-12-04
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Abstract

Abstract PCT No. PCT/AU95/00816 Sec. 371 Date Aug. 18, 1997 Sec. 102(e) Date Aug. 18, 1997 PCT Filed Dec. 4, 1995 PCT Pub. No. WO96/16693 PCT Pub. Date Jun. 6, 1996An iontophoresis method for delivenng an active substance or drug to a target tissue which includes the step of sandwiching the target tissue between a donor electrode and receptor electrode which are each electrically connnected to a power source wherein a current path between the donor electrode and the receptor electrode is maintained at a minimum value to enhance delivery of the active substance to the target tissue.

Inventors

  • 👤 Michael Stephen Roberts
  • 👤 Sheree Elizabeth Cross
  • 👤 Pam Muhtze Lai
  • 👤 Lawrence William Hirst

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 22:15
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/20; A61N1/30; A61N1/303; A61N1/306

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 99 words
A method of administration of an active substance to a sensitive target tissue selected from the eye, ear, nose or throat which includes the steps of: (i) inserting a first electrode into a nasal passage of a subject and applying a second electrode to the subject adjacent the eye or adjacent the ear wherein said first and second electrodes are each electrically connected to a power source and said target tissue is sandwiched between each of said electrodes to achieve a current path which is of minimal electrical resistance and (ii) delivering said active substance to said target tissue.
Claim 2
Independent Claim 99 words
A method of administration of an active substance to a sensitive target tissue selected from the eye, ear, nose or throat which includes the steps of: (i) inserting a first electrode into a nasal passage of a subject and applying a second electrode to the subject adjacent the eye or adjacent the ear wherein said first and second electrodes are each electrically connected to a power source and said target tissue is sandwiched between each of said electrodes to achieve a current path which is of minimal electrical resistance and (ii) delivering said active substance to said target tissue.
Claim 3
Dependent Claim 23 words
A method as claimed in claim 1 wherein the first electrode is a donor electrode and the second electrode is a receptor electrode.
Claim 4
Dependent Claim 15 words
A method as claimed in claim 2 wherein the donor electrode is a needle electrode.
Claim 5
Dependent Claim 15 words
A method as claimed in claim 2 wherein the donor electrode is a probe electrode.
Claim 6
Dependent Claim 17 words
A method as claimed in claim 2 wherein the donor electrode is a pad for topical administration.
Claim 7
Dependent Claim 58 words
A method as claimed in claim 2, wherein the donor electrode includes an electrode body formed from insulating material, a conductor passing through the electrode body and a compartment for storage of active substance located adjacent an outer end of the electrode body which is provided with access means whereby active substance can be delivered to adjacent tissue.
Claim 8
Dependent Claim 20 words
A method as claimed in claim 6 wherein the access means includes apertures in an external wall of the compartment.
Claim 9
Dependent Claim 21 words
A method as claimed in claim 6 wherein the access means includes dialysis membrane or porous membrane adjacent to the compartment.
Claim 10
Dependent Claim 28 words
A method as claimed in claim 6 wherein the electrode body has an outwardly extending conductor part or needle tip adjacent an outer end of the electrode body.
Claim 11
Dependent Claim 12 words
A method as claimed in claim 6 also including an insulating handle.
Claim 12
Dependent Claim 14 words
A method as claimed in claim 1 wherein the target tissue is the eye.
Claim 13
Dependent Claim 14 words
A method as claimed in claim 1 wherein the target tissue is the ear.
Claim 14
Dependent Claim 14 words
A method as claimed in claim 1 wherein the target tissue is the throat.
Claim 15
Dependent Claim 14 words
A method as claimed in claim 1 wherein the target tissue is the nose.

References Cited (Backward Citations)

US109367A Cited
US1740240A Cited
US2123980A Cited
US2525381A Cited
US3991755A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2002-12-13 2003-06-14 2003-12-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2006-12-13 2007-06-14 2007-12-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2010-12-13 2011-06-14 2011-12-14 $7700.00 Window Closed / Lapsed

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