US5989246A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Probe for heating body tissue
Assignee: Individual
•
Filing: 1993-06-29
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Granted: 1999-11-23
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Expires: 2013-06-29
Abstract
Abstract The invention concerns a probe for heating body tissue by means of high-intensity laser light, the probe having an optical fibre coupled to a laser source and a diffusor element located in the light-exit zone which is inserted into the body tissue. The diffusor element is made of a material which is highly transparent to the laser light but which contains highly reflective particles embedded in it. The probe is connected to a coolant circuit to cool the light-exit zone.
Inventors
- 👤 Raimund Kaufmann
- 👤 Hans-Joachim Schwarzmaier
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 19:59
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/06; A61N5/0601; A61B; A61B18/00; A61B18/18; A61B18/20; A61B18/22; A61B2018/2255; A61B2018/2261; A61N5/067
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
230 words
A probe for heating body tissue by high-intensity laser light from a laser light source, said probe comprising: a light guide for coupling to the laser light source and having an exit portion to be introduced into the body tissue; a diffuser element on the light guide made of a base material which is highly transparent to laser light; particles of material highly reflective to laser light embedded in the base material; a tubular sleeve surrounding and spaced from the light guide at a predetermined distance; the tubular sleeve having a cap at an end thereof being made of a material that is transparent to laser light and has good heat conductivity in the area of the diffuser element to transmit heat by conduction and by radiation to the body tissue; the diffuser element being spaced from the cap and surrounded by coolant with coolant between the cap and the diffuser element; the cap allowing isotropic scattering of laser light from the diffuser element; and means including a closed coolant passageway in the tubular sleeve having a channel for flowing coolant through the tubular sleeve toward the body tissue and surrounding the diffuser element to remove a substantial portion of the heat transmitted to the body tissue by heat conduction and from the body tissue, while the laser light source is being operated to produce heat radiation for tumor therapy.
Claim 2
Dependent Claim
230 words
A probe for heating body tissue by high-intensity laser light from a laser light source, said probe comprising: a light guide for coupling to the laser light source and having an exit portion to be introduced into the body tissue; a diffuser element on the light guide made of a base material which is highly transparent to laser light; particles of material highly reflective to laser light embedded in the base material; a tubular sleeve surrounding and spaced from the light guide at a predetermined distance; the tubular sleeve having a cap at an end thereof being made of a material that is transparent to laser light and has good heat conductivity in the area of the diffuser element to transmit heat by conduction and by radiation to the body tissue; the diffuser element being spaced from the cap and surrounded by coolant with coolant between the cap and the diffuser element; the cap allowing isotropic scattering of laser light from the diffuser element; and means including a closed coolant passageway in the tubular sleeve having a channel for flowing coolant through the tubular sleeve toward the body tissue and surrounding the diffuser element to remove a substantial portion of the heat transmitted to the body tissue by heat conduction and from the body tissue, while the laser light source is being operated to produce heat radiation for tumor therapy.
Claim 3
Dependent Claim
27 words
A probe according to claim 1, wherein the particles of highly reflective material are selected from the group consisting of barium sulphate, magnesium oxide and aluminum powder.
Claim 4
Dependent Claim
25 words
A probe according to claim 1 wherein the diffuser element material is selected from the group comprising glass, glass-like plastics, transparent adhesives and methyl acrylates.
Claim 5
Dependent Claim
20 words
A probe according to claim 1 wherein the particles of highly reflective material are homogeneously distributed in the transparent material.
Claim 6
Dependent Claim
26 words
A probe according to claim 1 wherein the particles of highly reflective material are distributed non-homogeneously in said transparent material dependent on a desired radiation characteristic.
Claim 7
Dependent Claim
20 words
A probe according to claim 1 wherein said diffuser element is shaped to produce an approximately spherical heat radiation characteristic.
Claim 8
Dependent Claim
20 words
A probe according to claim 1 wherein said diffuser element is shaped to produce an approximately cylindrical heat radiation characteristic.
Claim 9
Dependent Claim
35 words
A probe according to claim 1 wherein said light guide is hollow and has coolant flowing therein, said light guide and said outer sleeve being spaced to form the passageway for the coolant to flow.
Claim 10
Dependent Claim
48 words
A probe according to claim 1 wherein the tubular sleeve has a free probe end, a membrane divides the passageway in the tubular sleeve into at least two channels extending in parallel to the axis, and wherein said channels communicate in the area of the free probe end.
Claim 11
Dependent Claim
279 words
A probe for heating body tissue by high-intensity laser light from a laser light source, said probe comprising: a light guide for coupling to the laser light source and having an exit portion to be introduced into the body tissue; a diffuser element on the light guide made of a base material which is highly transparent to laser light; particles of material highly reflective to laser light embedded in the base material; a tubular sleeve surrounding and spaced from the light guide at a predetermined distance; the tubular sleeve being made of a material that is transparent to laser light and has good heat conductivity in the area of the diffuser element to transmit heat by conduction and by radiation to the body tissue; and means including a closed coolant passageway in the tubular sleeve having a channel for flowing coolant through the tubular sleeve toward the body tissue to remove a substantial portion of the heat transmitted to the body tissue by heat conduction and from the body tissue while the laser light source is being operated to produce heat radiation for tumor therapy; the tubular sleeve having a free probe end, an inner coaxial sleeve having a radially inner and outer sleeve, the radially inner sleeve surrounding the light guide and forming a first channel portion between said inner sleeve and said light guide and a radially inner one of said sleeves, and a second channel portion being formed between the two sleeves; the two sleeves being transparent and have good heat conductivity at least in the area of the diffuser element, and wherein said two channel portions communicate in the area of the free probe end.
Claim 12
Dependent Claim
279 words
A probe for heating body tissue by high-intensity laser light from a laser light source, said probe comprising: a light guide for coupling to the laser light source and having an exit portion to be introduced into the body tissue; a diffuser element on the light guide made of a base material which is highly transparent to laser light; particles of material highly reflective to laser light embedded in the base material; a tubular sleeve surrounding and spaced from the light guide at a predetermined distance; the tubular sleeve being made of a material that is transparent to laser light and has good heat conductivity in the area of the diffuser element to transmit heat by conduction and by radiation to the body tissue; and means including a closed coolant passageway in the tubular sleeve having a channel for flowing coolant through the tubular sleeve toward the body tissue to remove a substantial portion of the heat transmitted to the body tissue by heat conduction and from the body tissue while the laser light source is being operated to produce heat radiation for tumor therapy; the tubular sleeve having a free probe end, an inner coaxial sleeve having a radially inner and outer sleeve, the radially inner sleeve surrounding the light guide and forming a first channel portion between said inner sleeve and said light guide and a radially inner one of said sleeves, and a second channel portion being formed between the two sleeves; the two sleeves being transparent and have good heat conductivity at least in the area of the diffuser element, and wherein said two channel portions communicate in the area of the free probe end.
Claim 13
Dependent Claim
19 words
A probe according to claim 10 wherein in that the tubular sleeves surrounding the light guide are rigid tubes.
Claim 14
Dependent Claim
16 words
A probe according to claim 1 wherein the outer sleeve surrounding the light guide is flexible.
Claim 15
Dependent Claim
21 words
A probe according to claim 1 wherein the coolant has a sufficient viscosity to flow even at temperatures below 0° C.
Claim 16
Dependent Claim
24 words
A probe according to claim 13 further comprising said coolant which is a mixture of a 0.9% sodium chloride solution and alcohol or methanol.
Claim 17
Dependent Claim
21 words
A probe according to claim 1, wherein the materials forming at least the cap of the probe are nuclear magnetic resonance-compatible.
Claim 18
Dependent Claim
22 words
A probe according to claim 1 wherein a tip on the probe is adapted for puncturing solid tissue at its distal end.
Claim 19
Dependent Claim
20 words
A probe according to claim 1 wherein the cap of the tubular sleeve is made of diamond or quartz glass.
Claim 20
Independent Claim
177 words
A method of heating body tissue with a probe receiving high-intensity laser light from a light source, said method comprising the steps of: inserting the probe into the tissue; generating the laser light and transmitting the laser light through a light guide to a diffuser element at an exit end of the probe, the probe at the diffuser element being less than about 2.5 mm in diameter; applying at least 30 watts of power to the light guide probe; scattering the laser light in a desired solid angle from the diffuser element to the tissue; surrounding the diffuser element with coolant to cool the exit end of the probe; cooling the exit end of the probe and the tissue in contact therewith with a coolant that removes more than one-half of laser energy thereby removing a large portion of the heat that would be transmitted by conduction to the tissue in the immediate vicinity of the diffuser element; and heating the tissue primarily by radiation to a temperature increase of at least 7° C. for tumor therapy.
Claim 21
Independent Claim
177 words
A method of heating body tissue with a probe receiving high-intensity laser light from a light source, said method comprising the steps of: inserting the probe into the tissue; generating the laser light and transmitting the laser light through a light guide to a diffuser element at an exit end of the probe, the probe at the diffuser element being less than about 2.5 mm in diameter; applying at least 30 watts of power to the light guide probe; scattering the laser light in a desired solid angle from the diffuser element to the tissue; surrounding the diffuser element with coolant to cool the exit end of the probe; cooling the exit end of the probe and the tissue in contact therewith with a coolant that removes more than one-half of laser energy thereby removing a large portion of the heat that would be transmitted by conduction to the tissue in the immediate vicinity of the diffuser element; and heating the tissue primarily by radiation to a temperature increase of at least 7° C. for tumor therapy.
Claim 22
Dependent Claim
21 words
A method in accordance with claim 18 including a cooling system and removing about 80% or more of the laser energy.
Claim 23
Dependent Claim
27 words
A method in accordance with claim 18 including the step of cooling the temperature of the tissue close to the diffuser element down to about 0° C.
Claim 24
Dependent Claim
34 words
A method in accordance with claim 18 including the steps of providing power in the range of 30 watts to 100 watts, and removing about 80% to 90% of the power by the coolant.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-11-22 | 2003-05-24 | 2003-11-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-11-22 | 2007-05-24 | 2007-11-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-11-22 | 2011-05-24 | 2011-11-23 | $7700.00 | Window Closed / Lapsed |