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US5985559A Expired / Lapsed US ⏱️ 0.0 years remaining

System and method for preventing, diagnosing, and treating genetic and pathogen-caused disease

Assignee: Robert Bosch Healthcare Systems Inc
•
Filing: 1997-05-03
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Granted: 1999-11-16
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Expires: 2017-05-03
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Abstract

Abstract Genetic testing allows an individual to determine whether or not he or she has a predisposition to a certain disease. The degree of expressivity of a certain disease will be determined in part by an individual's environment and lifestyle. The present invention interprets a patient's gene sequence and his or her environment and lifestyle to come up with a personalized prognosis. This procedure can be repeated many times over the course of a disease state to monitor a patient's condition. In addition, disease-causing pathogens can also have their genes sequenced. Using these sequences in combination with information about a patient's environment and lifestyle, it is possible to come up with a personalized treatment plan, ideally to eliminate the pathogen. It is also possible to use the procedure described above to monitor the course of the disease-state produced by a pathogen. Finally, a genotype-to-phenotype map or database can be constructed for developing better treatments and for research purposes.

Inventors

  • 👤 Stephen J. Brown

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-06 05:01
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/0002; A61B5/41; A61B5/414; A61B5/416; A61B5/48; A61B5/4836; A61B5/4839; A61B5/68; A61B5/6887; A61B5/6896; G; G16; G16H; G16H10/00; G16H10/20; G16H40/00; G16H40/40; G16H40/60; G16H40/67; A61B2560/00; A61B2560/04; A61B2560/0443; A61B5/02; A61B5/0205; A61B5/08; A61B5/087; A61B5/145; A61B5/14532; G16H10/60

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 97 words
A system for developing a personalized treatment, the system comprising: a) a means for sequencing a gene and for providing at least one patient-specific gene sequence; b) a database of known gene sequences and associated scripts assigned to said known gene sequences; and c) a health monitor for interpreting said at least one patient-specific gene sequence, for receiving said associated scripts from said database, for presenting said associated scripts to a patient and for determining a degree of expressivity of a phenotype associated with a genotype based on a response of the patient to said associated scripts.
Claim 2
Independent Claim 97 words
A system for developing a personalized treatment, the system comprising: a) a means for sequencing a gene and for providing at least one patient-specific gene sequence; b) a database of known gene sequences and associated scripts assigned to said known gene sequences; and c) a health monitor for interpreting said at least one patient-specific gene sequence, for receiving said associated scripts from said database, for presenting said associated scripts to a patient and for determining a degree of expressivity of a phenotype associated with a genotype based on a response of the patient to said associated scripts.
Claim 3
Dependent Claim 17 words
The system of claim 1, wherein said associated scripts comprise questions about the patient's environment and lifestyle.
Claim 4
Dependent Claim 19 words
The system of claim 2, wherein said health monitor presents said associated scripts to the patient more than once.
Claim 5
Dependent Claim 17 words
The system of claim 1, wherein said means for sequencing a gene allows analysis of said gene.
Claim 6
Dependent Claim 25 words
The system of claim 1, wherein said database is remote from said health monitor and connected to said health monitor by means of a network.
Claim 7
Dependent Claim 22 words
The system of claim 1, wherein said response of the patient to said associated scripts is used to construct a genotype-to-phenotype map.
Claim 8
Dependent Claim 24 words
The system of claim 1, wherein said response of the patient to said associated scripts is used to construct a genotype phenotype knowledge base.
Claim 9
Dependent Claim 19 words
The system of claim 1, wherein said at least one patient-specific gene sequence is associated with a disease condition.

References Cited (Backward Citations)

US5307263A Cited
US5714319A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2002-11-15 2003-05-17 2003-11-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2006-11-15 2007-05-17 2007-11-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2010-11-15 2011-05-17 2011-11-16 $7700.00 Window Closed / Lapsed

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