US5983121A
Expired / Lapsed
US
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Absorption information measuring method and apparatus of scattering medium
Assignee: Hamamatsu Photonics KK
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Filing: 1997-08-28
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Granted: 1999-11-09
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Expires: 2017-08-28
Abstract
Abstract A method characterized by making modulated light having a predetermined modulation frequency component, incident to a scattering medium, receiving the modulated light having propagated inside the scattering medium to acquire measurement signals, detecting signals of the foregoing modulation frequency component from the measurement signals, obtaining amplitudes and inclinations of phase against modulation angular frequency, of the signals of the foregoing modulation frequency component, calculating a difference between absorption coefficients being primary information, based on a predetermined relation among the amplitudes, the inclinations of phase against modulation angular frequency and the difference between absorption coefficients, and calculating a difference of concentration of an absorptive constituent being secondary information, based on the difference between absorption coefficients.
Inventors
- 👤 Yutaka Tsuchiya
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 08:32
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/17; G01N21/47; G01N21/49
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
154 words
A method of measuring absorption information of a scattering medium, said method comprising: applying modulated light having a predetermined modulation frequency component to form a spot shape incident on a surface of a scattering medium comprising a measured object; acquiring respective measurement signals by receiving said modulated light having propagated inside said measured object at one or both of a plurality of different times and a plurality of position on said surface of said scattering medium; detecting, from each of said respective measurement signals, respective signals of said modulation frequency component; obtaining, from said respective signals of said modulation frequency component, sine components and cosine component slopes against modulation angular frequency; and calculating a difference between absorption coefficients of said measured object based upon a predetermined relation among said sine components, said cosine component slopes against modulation angular frequency, and a difference between absorption coefficients corresponding to different ones of said respective measurement signals.
Claim 2
Independent Claim
154 words
A method of measuring absorption information of a scattering medium, said method comprising: applying modulated light having a predetermined modulation frequency component to form a spot shape incident on a surface of a scattering medium comprising a measured object; acquiring respective measurement signals by receiving said modulated light having propagated inside said measured object at one or both of a plurality of different times and a plurality of position on said surface of said scattering medium; detecting, from each of said respective measurement signals, respective signals of said modulation frequency component; obtaining, from said respective signals of said modulation frequency component, sine components and cosine component slopes against modulation angular frequency; and calculating a difference between absorption coefficients of said measured object based upon a predetermined relation among said sine components, said cosine component slopes against modulation angular frequency, and a difference between absorption coefficients corresponding to different ones of said respective measurement signals.
Claim 3
Dependent Claim
47 words
A method according to claim 1, wherein a difference of concentration of an absorptive constituent is quantified based upon a predetermined relation among said difference between absorption coefficients, an absorption coefficient per unit concentration of an absorptive constituent, and said difference of concentration of said absorptive constituent.
Claim 4
Independent Claim
181 words
A method of measuring absorption information of a scattering medium, said method comprising: applying a plurality of modulated light beams to form a spot shape incident on a surface of a scattering medium comprising a measured object, each of said plurality of modulated light beams having a predetermined modulation frequency component and a different wavelength at which scattering coefficients of said measured object are substantially equal to one another; acquiring respective measurement signals for said different wavelengths by receiving said modulated light beams having propagated inside said measured object at a predetermined position on said surface of said scattering medium; detecting, from each of said respective measurement signals, respective signals of said modulation frequency component; obtaining, from said respective signals of said modulation frequency component, sine components and cosine component slopes against modulation angular frequency; and calculating a difference between absorption coefficients of said measured object at said respective wavelengths based upon a predetermined relation among said sine components, said cosine component slopes against modulation angular frequency, and said difference between absorption coefficients of said measuring object at said respective wavelengths.
Claim 5
Independent Claim
181 words
A method of measuring absorption information of a scattering medium, said method comprising: applying a plurality of modulated light beams to form a spot shape incident on a surface of a scattering medium comprising a measured object, each of said plurality of modulated light beams having a predetermined modulation frequency component and a different wavelength at which scattering coefficients of said measured object are substantially equal to one another; acquiring respective measurement signals for said different wavelengths by receiving said modulated light beams having propagated inside said measured object at a predetermined position on said surface of said scattering medium; detecting, from each of said respective measurement signals, respective signals of said modulation frequency component; obtaining, from said respective signals of said modulation frequency component, sine components and cosine component slopes against modulation angular frequency; and calculating a difference between absorption coefficients of said measured object at said respective wavelengths based upon a predetermined relation among said sine components, said cosine component slopes against modulation angular frequency, and said difference between absorption coefficients of said measuring object at said respective wavelengths.
Claim 6
Dependent Claim
46 words
The method according to claim 3, further comprising quantifying a concentration of the absorptive constituent based upon a predetermined relation among said difference between absorption coefficients, absorption coefficients per unit concentration of an absorptive constituent at said respective wavelengths, and said concentration of said absorptive constituent.
Claim 7
Dependent Claim
36 words
The method according to claim 3, wherein said measurement signals comprise a plurality of measurement signals obtained when said light beams are received at a plurality of different positions on said surface of said scattering medium.
Claim 8
Independent Claim
171 words
An apparatus for measuring absorption information of a scattering medium, said apparatus comprising: a light incidence section for applying modulated light having a predetermined modulation frequency component to form a spot shape incident on a surface of a scattering medium comprising a measured object; a photodetection section for acquiring respective measurement signals by receiving said modulated light having propagated inside said measured object at one or both of a plurality of different times and a plurality of positions on said surface of said scattering medium; a signal detecting section for detecting, from said respective measurement signals, respective signals of said modulation frequency component; a first arithmetic section for calculating, from said respective signals of said modulation frequency component, sine components and cosine component slopes against modulation angular frequency; and a second arithmetic section for calculating a difference between absorption coefficients of said measuring object based upon a predetermined relation among said sine components, said cosine component slopes against modulation angular frequency, and said difference between absorption coefficients of said measuring object.
Claim 9
Independent Claim
171 words
An apparatus for measuring absorption information of a scattering medium, said apparatus comprising: a light incidence section for applying modulated light having a predetermined modulation frequency component to form a spot shape incident on a surface of a scattering medium comprising a measured object; a photodetection section for acquiring respective measurement signals by receiving said modulated light having propagated inside said measured object at one or both of a plurality of different times and a plurality of positions on said surface of said scattering medium; a signal detecting section for detecting, from said respective measurement signals, respective signals of said modulation frequency component; a first arithmetic section for calculating, from said respective signals of said modulation frequency component, sine components and cosine component slopes against modulation angular frequency; and a second arithmetic section for calculating a difference between absorption coefficients of said measuring object based upon a predetermined relation among said sine components, said cosine component slopes against modulation angular frequency, and said difference between absorption coefficients of said measuring object.
Claim 10
Independent Claim
51 words
The apparatus according to clam 6, wherein said second arithmetic section further calculates a difference of concentration of an absorptive constituent based upon a predetermined relation among said difference between absorption coefficients, an absorption coefficient per unit concentration of said absorptive constituent, and said difference of concentration of said absorptive constituent.
Claim 11
Independent Claim
51 words
The apparatus according to clam 6, wherein said second arithmetic section further calculates a difference of concentration of an absorptive constituent based upon a predetermined relation among said difference between absorption coefficients, an absorption coefficient per unit concentration of said absorptive constituent, and said difference of concentration of said absorptive constituent.
Claim 12
Independent Claim
193 words
An apparatus for measuring absorption information of a scattering medium, said apparatus comprising: a light incidence section for applying a plurality of modulated light beams to form a spot shaped incident on a surface of a scattering medium comprising a measured object, each of said plurality of modulated light beams having a predetermined modulation frequency component and having a predetermined different wavelength at which scattering coefficients of said measured object are substantially equal to one another; a photodetection section for acquiring respective measurement signals for said different wavelengths by receiving said modulated light beams having propagated inside said measured object at a predetermined position on said surface of said scattering medium; a signal detecting section for detecting, from said respective measurement signals, respective signals of said modulation frequency component; a first arithmetic section for obtaining, from said respective signals of said modulation frequency component, sine components and cosine component slopes against modulation angular frequency; and a second arithmetic section for calculating a difference between absorption coefficients of said measuring object based upon a predetermined relation among said sine components, said sine component slopes against modulation angular frequency, and said difference between absorption coefficients.
Claim 13
Independent Claim
193 words
An apparatus for measuring absorption information of a scattering medium, said apparatus comprising: a light incidence section for applying a plurality of modulated light beams to form a spot shaped incident on a surface of a scattering medium comprising a measured object, each of said plurality of modulated light beams having a predetermined modulation frequency component and having a predetermined different wavelength at which scattering coefficients of said measured object are substantially equal to one another; a photodetection section for acquiring respective measurement signals for said different wavelengths by receiving said modulated light beams having propagated inside said measured object at a predetermined position on said surface of said scattering medium; a signal detecting section for detecting, from said respective measurement signals, respective signals of said modulation frequency component; a first arithmetic section for obtaining, from said respective signals of said modulation frequency component, sine components and cosine component slopes against modulation angular frequency; and a second arithmetic section for calculating a difference between absorption coefficients of said measuring object based upon a predetermined relation among said sine components, said sine component slopes against modulation angular frequency, and said difference between absorption coefficients.
Claim 14
Dependent Claim
50 words
The apparatus according to claim 8, wherein said second arithmetic section further quantifies a concentration of an absorptive constituent based upon a predetermined relation among said difference between absorption coefficients, absorption coefficients per unit concentration of an absorptive constituent at said different wavelengths, and said concentration of said absorptive constituent.
Claim 15
Dependent Claim
63 words
The apparatus according to claim 8, wherein said photodetection section comprises a light receiving section adapted to receive said light beams at a plurality of positions on said surface of said scattering medium, and wherein said measurement signals comprise a plurality of measurement signals obtained when said light beams are received at a plurality of positions on said surface of said scattering medium.
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