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US5910102A Expired / Lapsed US ⏱️ 0.0 years remaining

Conversion of beta radiation to gamma radiation for intravascular radiation therapy

Assignee: Boston Scientific Scimed Inc
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Filing: 1997-01-10
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Granted: 1999-06-08
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Expires: 2017-01-10
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Abstract

Abstract A method and apparatus for inhibiting restenosis of arteries utilizing Bremstralung created radiation. A preferred apparatus includes an elongate shaft having a heavy-metal envelope disposed on the distal end. The apparatus can include a second elongate shaft slidably disposed parallel to the first shaft for increasing the outer diameter of the envelope by proximally pulling the envelope distal end relative to the envelope proximal end.

Inventors

  • 👤 Roger N. Hastings

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-06 09:31
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/10; A61N5/1001; A61N5/1002; A61N2005/1004

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 35 words
An elongate intra-vascular device for emitting radiation comprising: a first elongate shaft member having a distal region; a heavy-metal envelope attached to said first shaft distal region and a Beta radiation source within said envelope.
Claim 2
Dependent Claim 35 words
An elongate intra-vascular device for emitting radiation comprising: a first elongate shaft member having a distal region; a heavy-metal envelope attached to said first shaft distal region and a Beta radiation source within said envelope.
Claim 3
Dependent Claim 40 words
A device as recited in claim 1, wherein said envelope has an interior cavity, wherein said first elongate shaft includes a first lumen having an opening in said distal region, said opening being in communication with said envelope interior cavity.
Claim 4
Dependent Claim 23 words
A device as recited in claim 2, wherein said envelope has an outer diameter, further comprising means for increasing said envelope outer diameter.
Claim 5
Dependent Claim 73 words
A device as recited in claim 3, wherein said envelope has a proximal portion and a distal portion, wherein said means for increasing said envelope outer diameter includes a second elongate shaft having a distal region, said second elongate shaft slidably disposed parallel to said first elongate shaft, said envelope proximal portion being attached to said first shaft distal region, and said envelope distal portion being attached to said second shaft distal region.
Claim 6
Dependent Claim 18 words
A device as recited in claim 4, wherein said second shaft is slidably disposed within said first shaft.
Claim 7
Dependent Claim 16 words
A device as recited in claim 5, wherein said envelope includes a plurality of longitudinal strips.
Claim 8
Dependent Claim 14 words
A device as recited in claim 6, wherein said strips have laterally overlapping regions.
Claim 9
Dependent Claim 28 words
A device as recited in claim 6, wherein said heavy-metal includes gold and said strips include material selected from the group consisting of gold foil and gold film.
Claim 10
Dependent Claim 16 words
A device as recited in claim 6, further comprising means for centering said Beta radiation source.
Claim 11
Dependent Claim 20 words
A device as recited in claim 9, further comprising means for perfusing blood through said radiation emitting device distal region.
Claim 12
Dependent Claim 23 words
A device as recited in claim 1, wherein said heavy-metal is selected from the group consisting of gold, tantalum, tungsten, platinum and iridium.
Claim 13
Dependent Claim 46 words
An elongate intra-vascular radiation emitting assembly having a distal region comprising: a first elongate shaft member having a distal region; a heavy-metal envelope attached to said first shaft distal region for disposing a Beta radiation source within; and a Beta radiation source disposed within said envelope.
Claim 14
Dependent Claim 46 words
An elongate intra-vascular radiation emitting assembly having a distal region comprising: a first elongate shaft member having a distal region; a heavy-metal envelope attached to said first shaft distal region for disposing a Beta radiation source within; and a Beta radiation source disposed within said envelope.
Claim 15
Independent Claim 82 words
A method for inhibiting restenosis at a site comprising the steps: providing an elongate intra-vascular radiation emitting device having a distal region including a first elongate shaft having a distal region and a heavy-metal envelope attached to said first shaft distal region for disposing a Beta radiation source within; providing a Beta radiation source; advancing said radiation device distal region to said site; inserting said Beta radiation source within said envelope; causing said envelope to emit Bremstralung created radiation near said site.
Claim 16
Independent Claim 82 words
A method for inhibiting restenosis at a site comprising the steps: providing an elongate intra-vascular radiation emitting device having a distal region including a first elongate shaft having a distal region and a heavy-metal envelope attached to said first shaft distal region for disposing a Beta radiation source within; providing a Beta radiation source; advancing said radiation device distal region to said site; inserting said Beta radiation source within said envelope; causing said envelope to emit Bremstralung created radiation near said site.
Claim 17
Dependent Claim 23 words
A method as recited in claim 13, wherein said heavy-metal is selected from the group consisting of gold, tantalum, tungsten, platinum and iridium.
Claim 18
Dependent Claim 32 words
A method as recited in claim 13, wherein said Beta source is selected from the group of Beta emitters consisting of phosphorus 32, strontium 90, iodine 131, sulfur 35, and carbon 14.
Claim 19
Dependent Claim 32 words
A method as recited in claim 13, wherein said emitted Bremstralung created radiation is delivered to the tunic adventitia vessel layer in a dose ranging from about 15 to about 30 grays.
Claim 20
Dependent Claim 16 words
A method as recited in claim 13, wherein said emitted Bremstralung created radiation includes Gamma rays.
Claim 21
Dependent Claim 16 words
A method as recited in claim 13, wherein said emitted Bremstralung created radiation includes X rays.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2002-06-07 2002-12-07 2003-06-08 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2006-06-07 2006-12-07 2007-06-08 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2010-06-07 2010-12-07 2011-06-08 $7700.00 Window Closed / Lapsed

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