US5865794A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Drug delivery catheter
Assignee: Abbott Cardiovascular Systems Inc
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Filing: 1997-01-23
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Granted: 1999-02-02
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Expires: 2017-01-23
Abstract
Abstract A device and method for the localized treatment of vasculature with drugs and medicaments is described herein. Centrifugal force is used to drive a material from a reservoir to the outer surface of the application device and thereby deliver the treatment substance to the chosen area.
Inventors
- 👤 Anthony J. Castro
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:27
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/22; A61M; A61M25/00; A61B2017/22082; A61B2017/22084; A61M31/00
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
138 words
A device for the application of medicaments from a rotatable drive cable-equipped catheter introduced into a biological conduit, the device comprising: a rotatable and axially translatable applicator including an outer surface defining a proximal end attachable to the catheter drive cable, a distal end, and a side portion; and an inner surface defining a reservoir for medicaments; and at least one medicament delivery path in the side portion of the applicator, originating in the reservoir and terminating in an opening on the outer surface of the applicator; a medicament being substantially retainable within the reservoir against gravity and during introduction of the device into the biological conduit; the medicament being substantially deliverable from the reservoir upon rotation of the applicator within the biological conduit, whereby the medicament is deliverable to the biological conduit upon rotation of the applicator.
Claim 2
Independent Claim
138 words
A device for the application of medicaments from a rotatable drive cable-equipped catheter introduced into a biological conduit, the device comprising: a rotatable and axially translatable applicator including an outer surface defining a proximal end attachable to the catheter drive cable, a distal end, and a side portion; and an inner surface defining a reservoir for medicaments; and at least one medicament delivery path in the side portion of the applicator, originating in the reservoir and terminating in an opening on the outer surface of the applicator; a medicament being substantially retainable within the reservoir against gravity and during introduction of the device into the biological conduit; the medicament being substantially deliverable from the reservoir upon rotation of the applicator within the biological conduit, whereby the medicament is deliverable to the biological conduit upon rotation of the applicator.
Claim 3
Dependent Claim
50 words
For the removal of tissue from a biological conduit, a medicament-applying device as set forth in claim 1 further comprising a cutting edge disposed on the outer surface of the distal end of the applicator whereby a medicament is deliverable as the cutting edge is applied to the biological conduit.
Claim 4
Dependent Claim
31 words
The device of claim 1 further comprising a sealing plug in the distal end of the applicator, the sealing plug being penetrable to permit injection of a medicament into the reservoir.
Claim 5
Dependent Claim
15 words
The device of claim 1 further comprising a porous absorbent material disposed within the reservoir.
Claim 6
Dependent Claim
14 words
The device of claim 1 wherein the medicament delivery path is of capillary dimensions.
Claim 7
Dependent Claim
28 words
The device of claim 1 wherein the medicament delivery path terminates in a slit of capillary dimensions in the outer surface of the side portion of the applicator.
Claim 8
Independent Claim
163 words
A method for application of medicaments within a biological conduit, the method comprising the steps of: providing a catheter comprising a rotatable drive cable; providing within the catheter a rotatable and axially translatable applicator including an outer surface defining a side portion, a distal end, a proximal end attached to the catheter drive cable; an inner surface defining a reservoir for medicaments; and at least one medicament delivery path originating in the reservoir and terminating in an opening on the outer surface of the applicator; introducing the catheter into a biological conduit and advancing the catheter to a treatment site therein; and rotating the applicator at a speed sufficient to force medicament from the reservoir into the biological conduit via the delivery path; whereby the medicament is substantially retained within the reservoir against gravity and during introduction of the device into the biological conduit, and the medicament is substantially delivered from the reservoir into the biological conduit when the applicator is rotated therein.
Claim 9
Independent Claim
163 words
A method for application of medicaments within a biological conduit, the method comprising the steps of: providing a catheter comprising a rotatable drive cable; providing within the catheter a rotatable and axially translatable applicator including an outer surface defining a side portion, a distal end, a proximal end attached to the catheter drive cable; an inner surface defining a reservoir for medicaments; and at least one medicament delivery path originating in the reservoir and terminating in an opening on the outer surface of the applicator; introducing the catheter into a biological conduit and advancing the catheter to a treatment site therein; and rotating the applicator at a speed sufficient to force medicament from the reservoir into the biological conduit via the delivery path; whereby the medicament is substantially retained within the reservoir against gravity and during introduction of the device into the biological conduit, and the medicament is substantially delivered from the reservoir into the biological conduit when the applicator is rotated therein.
Claim 10
Dependent Claim
69 words
For the removal of tissue from a biological conduit, a medicament-applying method as set forth in claim 7 wherein the applicator further comprises a cutting edge disposed on the outer surface of the distal end of the applicator and the method comprises the additional step of applying the cutting edge to the biological conduit, whereby medicament is delivered to the biological conduit as the cutting edge is applied thereto.
Claim 11
Dependent Claim
38 words
The method of claim 7 wherein the applicator further comprises a penetrable sealing plug in the distal end thereof and wherein the method comprises the additional step of injecting a medicament into the reservoir through the sealing plug.
Claim 12
Dependent Claim
18 words
The method of claim 7 wherein the applicator further comprises a porous absorbent material disposed within the reservoir.
Claim 13
Dependent Claim
14 words
The method of claim 7 wherein the medicament delivery path is of capillary dimensions.
Claim 14
Dependent Claim
28 words
The method of claim 7 wherein the medicament delivery path terminates in a slit of capillary dimensions in the outer surface of the side portion of the applicator.
Claim 15
Dependent Claim
13 words
The method of claim 7 wherein the biological conduit is a blood vessel.
Claim 16
Dependent Claim
14 words
The method of claim 7 wherein the biological conduit is a coronary blood vessel.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-02-01 | 2002-08-03 | 2003-02-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-02-01 | 2006-08-03 | 2007-02-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-02-01 | 2010-08-03 | 2011-02-02 | $7700.00 | Window Closed / Lapsed |