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US5833615A Expired / Lapsed US ⏱️ 0.0 years remaining

Excitation enhanced ultrasound system

Assignee: Thomas Jefferson University
•
Filing: 1997-05-09
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Granted: 1998-11-10
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Expires: 2017-05-09
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Abstract

Abstract The present invention relates generally to an ultrasound system and method, and more particularly to an excitation enhanced ultrasound system and method. The system employs at least one excitation signal as a "flashlight" for exciting ultrasonic microbubbles contained in an ultrasound contrast agent. The system further employs at least one ultrasound imaging signal for imaging structures and blood flow within an object. The excitation signal excites and expands the microbubbles which increase the amount of returned ultrasound imaging signals scattered and returned by an object. This process increases the signal to noise ratio of the returning imaging signal sufficiently to provide exciter weighted imaging, blood pool imaging, and harmonic imaging, facilitating improved diagnostic ultrasound and therapeutic ultrasound.

Inventors

  • 👤 Yunqiu Wu
  • 👤 Flemming Forsberg
  • 👤 Barry Goldberg

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 05:12
CPC Classifications
G; G01; G01S; G01S7/00; G01S7/52; G01S7/52017; G01S7/52019; G01S7/5202; G01S7/52022; A; A61; A61B; A61B8/00; A61B8/06; A61B8/48; A61B8/481; G01S7/52023; G01S7/52036; G01S7/52038

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 89 words
An excitation enhanced ultrasound imaging system comprising: at least one exciter for transmitting an excitation signal capable of exciting microbubbles contained within an object, and an ultrasound imaging system in operative communication with said exciter, said ultrasound imaging system capable of transmitting at least one imaging signal separate from said excitation signal and being capable of receiving ultrasound imaging signals scattered and returned by microbubbles excited by said excitation system and said object, wherein said ultrasound imaging system produces an image from said received imaging signals using pulse-echo techniques.
Claim 2
Dependent Claim 89 words
An excitation enhanced ultrasound imaging system comprising: at least one exciter for transmitting an excitation signal capable of exciting microbubbles contained within an object, and an ultrasound imaging system in operative communication with said exciter, said ultrasound imaging system capable of transmitting at least one imaging signal separate from said excitation signal and being capable of receiving ultrasound imaging signals scattered and returned by microbubbles excited by said excitation system and said object, wherein said ultrasound imaging system produces an image from said received imaging signals using pulse-echo techniques.
Claim 3
Dependent Claim 42 words
The system of claim 1, wherein said exciter and said ultrasound imaging system are operatively coupled to a pulse controller, said pulse controller controlling the transmitting of said excitation signals and the receiving of said imaging signals according to a desired sequence.
Claim 4
Dependent Claim 44 words
The system of claim 1, wherein said exciter and said ultrasound system utilize a single aperture comprising at least one element capable of transmitting a said excitation signals, and further comprising at least one transducer element capable of transmitting and receiving said imaging signal.
Claim 5
Dependent Claim 25 words
The system of claim 3, wherein said at least one transducer element comprises a wideband elements capable of receiving harmonic components of said imaging signals.
Claim 6
Dependent Claim 14 words
The system of claim 1, wherein said excitation signal is a pulsed acoustic signal.
Claim 7
Dependent Claim 15 words
The system of claim 1, wherein said exciter comprises an excitation element and a pulser.
Claim 8
Dependent Claim 49 words
The system of claim 1, wherein said at least one exciter comprises a plurality of elements for transmitting a plurality excitation signals, and said ultrasound imaging system comprises at least one transmitting element and at least one wideband receiving element capable of receiving harmonic components of said imaging signals.
Claim 9
Dependent Claim 22 words
The system of claim 2, wherein said pulse controller controls the formation of exciter weighted imaging, blood pool imaging, and harmonic imaging.
Claim 10
Dependent Claim 30 words
The system of claim 2, wherein said pulse controller controls the transmission of said excitation signals and receiving of said imaging signals according to a desired sequence for diagnostic ultrasound.
Claim 11
Dependent Claim 30 words
The system of claim 2, wherein said pulse controller controls the transmission of said excitation signals and receiving of said imaging signals according to a desired sequence for therapeutic ultrasound.
Claim 12
Dependent Claim 124 words
An excitation enhanced ultrasound imaging system comprising: at least one exciter for transmitting an excitation signal capable of exciting microbubbles contained within an object, an ultrasound imaging system in operative communication with said exciter, said ultrasound imaging system capable of transmitting at least one imaging signal separate from said excitation signal and capable of receiving imaging signals that are scattered and returned by microbubbles excited by said excitation system and said object, and a pulse controller operatively coupled to said exciter and said ultrasound imaging system, said pulse controller controlling the transmission of said excitation signals and the receiving of said imaging signals according to a desired sequence, wherein said ultrasound imaging system produces an image from said received imaging signals using pulse-echo techniques.
Claim 13
Dependent Claim 124 words
An excitation enhanced ultrasound imaging system comprising: at least one exciter for transmitting an excitation signal capable of exciting microbubbles contained within an object, an ultrasound imaging system in operative communication with said exciter, said ultrasound imaging system capable of transmitting at least one imaging signal separate from said excitation signal and capable of receiving imaging signals that are scattered and returned by microbubbles excited by said excitation system and said object, and a pulse controller operatively coupled to said exciter and said ultrasound imaging system, said pulse controller controlling the transmission of said excitation signals and the receiving of said imaging signals according to a desired sequence, wherein said ultrasound imaging system produces an image from said received imaging signals using pulse-echo techniques.
Claim 14
Independent Claim 146 words
A method for an excitation enhanced ultrasound imaging system comprising the steps of: exciting microbubbles with an exciter transmitting at least one excitation signal capable of exciting microbubbles contained in an object, imaging said microbubbles and said object with an ultrasound imaging system in operative communication with said exciter, said ultrasound imaging system capable of transmitting at least one imaging signal separate from said excitation signal and capable of receiving imaging signals that are scattered and returned by microbubbles excited by said excitation system and said object, and sequencing said excitation signals and said imaging signals with a pulse controller operatively coupled to said exciter and said ultrasound imaging system, said pulse controlling the transmission of said excitation signals and the receiving of said imaging signals according to a sequence, wherein said ultrasound imaging system produces an image from said received imaging signals using pulse-echo techniques.
Claim 15
Independent Claim 146 words
A method for an excitation enhanced ultrasound imaging system comprising the steps of: exciting microbubbles with an exciter transmitting at least one excitation signal capable of exciting microbubbles contained in an object, imaging said microbubbles and said object with an ultrasound imaging system in operative communication with said exciter, said ultrasound imaging system capable of transmitting at least one imaging signal separate from said excitation signal and capable of receiving imaging signals that are scattered and returned by microbubbles excited by said excitation system and said object, and sequencing said excitation signals and said imaging signals with a pulse controller operatively coupled to said exciter and said ultrasound imaging system, said pulse controlling the transmission of said excitation signals and the receiving of said imaging signals according to a sequence, wherein said ultrasound imaging system produces an image from said received imaging signals using pulse-echo techniques.

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2001-11-09 2002-05-11 2002-11-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2005-11-09 2006-05-11 2006-11-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2009-11-09 2010-05-11 2010-11-10 $7700.00 Window Closed / Lapsed

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