US5800529A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Close vascularization implant material
Assignee: Baxalta GmbH
•
Filing: 1995-06-07
•
Granted: 1998-09-01
•
Expires: 2015-06-07
Abstract
Abstract A device for implantation in a host having a material at an interface between the host and the device, said material having a conformation which results in growth of vascular structures by the host close to the interface.
Inventors
- 👤 James H. Brauker
- 👤 Robert C. Johnson
- 👤 Laura A. Martinson
- 👤 Ronald S. Hill
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:53
CPC Classifications
A; A61; A61F; A61F2/00; A61L; A61L29/00; A61L29/08; A61L29/085; A61F2/02; A61F2/022; A61L27/00; A61L27/36; A61L27/38; A61L27/3839; A61L27/50; A61L27/56; A61L29/005; A61L29/14; A61L29/146; A61B; A61B5/00; A61B5/145; A61B5/14532; A61B5/41; A61B5/413; Y; Y10; Y10S; Y10S623/00; Y10S623/92; Y10S623/924; Y10S623/925
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
103 words
A device for implantation in a host having a material at an interface between the host and the device, said material having (a) a nominal pore size from about 0.6 to about 20 microns which comprise frames of elongated strands of material that are less than 5 microns in all but the longest dimension wherein said frames define apertures which interconnect to form three-dimensional cavities which permit substantially all host inflammatory cells migrating into the cavities to maintain a rounded morphology; and (b) a conformation which results in growth of vascular structures by the host close to but not substantially into the interface.
Claim 2
Independent Claim
103 words
A device for implantation in a host having a material at an interface between the host and the device, said material having (a) a nominal pore size from about 0.6 to about 20 microns which comprise frames of elongated strands of material that are less than 5 microns in all but the longest dimension wherein said frames define apertures which interconnect to form three-dimensional cavities which permit substantially all host inflammatory cells migrating into the cavities to maintain a rounded morphology; and (b) a conformation which results in growth of vascular structures by the host close to but not substantially into the interface.
Claim 3
Dependent Claim
42 words
The device of claim 1 where the conformation of the material includes three dimensional cavities and irregularities so that host inflammatory cells in contact with the cavities and irregularities can conform to and enter the cavities and irregularities, and do not flatten.
Claim 4
Dependent Claim
19 words
The device of claim 1 where said vascular structures grow to within about one cell layer of the material.
Claim 5
Dependent Claim
137 words
The device of claim 1 where the material is selected from the group consisting of: 1) Millipore® Mixed Esters Cellulose, membrane pore size 1.2; 2) Millipore® Mixed Esters Cellulose, membrane pore size 8.0; 3) Satorious®, Cellulose Acetate, membrane pore size 0.8; 4) Satorious®, Cellulose Acetate, membrane pore size 1.2; 4) Satorious®, Cellulose Acetate, membrane pore size 3.0; 6) Satorious®, Cellulose Acetate, membrane pore size 5.0; 7) Satorious®, Cellulose Acetate, membrane pore size 8.0; 8) Gore®, PTFE/Polyester, membrane pore size 1.0; 9) Gore®, PTFE/Polyester, membrane pore size 3.0; 10) Gore®, PTFE/Polyester, membrane pore size 5.0; 11) Gore®, PTFE/Polyester, membrane pore size 10-15; 12) Gore®, PTFE/Polypropylene, membrane pore size 3.0; 13) Gelman®, Versapore®, membrane pore size 0.8; 14) Gelman®, Versapore®, membrane pore size 1.2; 15) Gelman®, Versapore®, membrane pore size 3.0; and 16) Gelman®, Versapore®, membrane pore size 5.0.
Claim 6
Dependent Claim
13 words
The device of claim 1 where the material is impermeable to immune factors.
Claim 7
Independent Claim
125 words
A device for implantation in a host having a first material at an interface between the host and the device, said first material having (a) a nominal pore size ranging from about 0.6 to about 20 microns which comprise frames of elongated strands of material that are less than 5 microns in all but the longest dimension wherein said frames define apertures which interconnect to form three-dimensional cavities which permit substantially all host inflammatory cells migrating into the cavities to maintain a rounded morphology; and (b) a conformation which results in growth of vascular structures by the host close to but not substantially into the interface, the device further having a second material underlying the first material, the second material being impermeable to immune factors.
Claim 8
Independent Claim
125 words
A device for implantation in a host having a first material at an interface between the host and the device, said first material having (a) a nominal pore size ranging from about 0.6 to about 20 microns which comprise frames of elongated strands of material that are less than 5 microns in all but the longest dimension wherein said frames define apertures which interconnect to form three-dimensional cavities which permit substantially all host inflammatory cells migrating into the cavities to maintain a rounded morphology; and (b) a conformation which results in growth of vascular structures by the host close to but not substantially into the interface, the device further having a second material underlying the first material, the second material being impermeable to immune factors.
Claim 9
Dependent Claim
12 words
The device of claim 1 where the device is an indwelling catheter.
Claim 10
Dependent Claim
28 words
The device of claim 1 where the device is an indwelling sensor and where the material is permeable to an analyte in the host detectable by the sensor.
Claim 11
Dependent Claim
12 words
The device of claim 1 where the device is a breast prosthesis.
Claim 12
Dependent Claim
14 words
The device of claim 1 where the device is a container for cellular implantation.
Claim 13
Dependent Claim
36 words
The device of claim 1 where the material is selected from the group consisting of polyethylene, polypropylene, polytetrafluoroethylene (PTFE), cellulose acetate, cellulose nitrate, polycarbonate, polyester, nylon, polysulfone, mixed esters of cellulose, polyvinylidene difluoride, silicone, and polyacrylonitrile.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-08-31 | 2002-03-02 | 2002-09-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-08-31 | 2006-03-02 | 2006-09-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-08-31 | 2010-03-02 | 2010-09-01 | $7700.00 | Window Closed / Lapsed |