US5795286A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Radioisotope impregnated sheet of biocompatible material for preventing scar tissue formation
Assignee: Gaylord Container Corp
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Filing: 1996-08-15
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Granted: 1998-08-18
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Expires: 2016-08-15
Abstract
Abstract This invention is a radioisotope impregnated material sheet or mesh designed to be placed between internal body tissues to prevent the formation of post-operative adhesions, which adhesions are really scar tissue formation. This mesh or gauze into which the isotope is placed may be either a permanent implant or it may be biodegradable. By impregnating an existing product such as the Johnson & Johnson SURGICEL™ absorbable hemostat gauze-like sheet with a beta emitting radioisotope such as phosphorous-32 with has a relatively short effective range of approximately 4 mm, the biodegradable mesh would act as a barrier to cell proliferation and hence be a deterrent to the formation of adhesions.
Inventors
- 👤 Robert E. Fischell
- 👤 David R. Fischell
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 09:05
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/10; A61N5/1001; A61N5/1028; A61N5/1029
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
50 words
A biodegradable sheet of material adapted for implantation between tissues of a human body, at least part of said sheet of material including a radioisotope, said radioisotope being placed within a soluble structure which is said biodegradable sheet of material so that the radioisotope becomes dispersed into the human body.
Claim 2
Dependent Claim
50 words
A biodegradable sheet of material adapted for implantation between tissues of a human body, at least part of said sheet of material including a radioisotope, said radioisotope being placed within a soluble structure which is said biodegradable sheet of material so that the radioisotope becomes dispersed into the human body.
Claim 3
Dependent Claim
15 words
The apparatus of claim 1 wherein the radioisotope is embedded within the sheet of material.
Claim 4
Dependent Claim
15 words
The apparatus of claim 1 wherein the radioisotope is coated onto the sheet of material.
Claim 5
Dependent Claim
13 words
The apparatus of claim 1 wherein the radioisotope is predominantly a beta emitter.
Claim 6
Dependent Claim
11 words
The apparatus of claim 4 wherein the beta emitter is phosphorous-32.
Claim 7
Dependent Claim
17 words
The apparatus of claim 1 wherein the sheet of material is in the form of a mesh.
Claim 8
Dependent Claim
14 words
The apparatus of claim 1 wherein the radioisotope is embedded within the biodegradable material.
Claim 9
Dependent Claim
14 words
The apparatus of claim 1 wherein the radioisotope is coated onto the biodegradable material.
Claim 10
Dependent Claim
13 words
The apparatus of claim 1 wherein the radioisotope is predominantly a beta emitter.
Claim 11
Independent Claim
64 words
A method for the prevention of scar tissue formation and adhesions associated with a surgical procedure, the method comprising the following steps: a) place a radioisotope that is free from encapsulation into a non-soluble structure into a biodegradable sheet of material: and b) place the sheet of material containing the radioisotope into a human body between tissues that are separated by a surgical incision.
Claim 12
Independent Claim
64 words
A method for the prevention of scar tissue formation and adhesions associated with a surgical procedure, the method comprising the following steps: a) place a radioisotope that is free from encapsulation into a non-soluble structure into a biodegradable sheet of material: and b) place the sheet of material containing the radioisotope into a human body between tissues that are separated by a surgical incision.
Claim 13
Dependent Claim
24 words
The method of claim 10 including the step of closing the surgical incision after the sheet of material is placed between the separated tissues.
Claim 14
Dependent Claim
38 words
A biodegradable material adapted for implantation between tissues of a human body, at least part of said biodegradable material including a radioisotope, said biodegradable material and said radioisotope each being adapted to be absorbed into the human body.
Claim 15
Dependent Claim
38 words
A biodegradable material adapted for implantation between tissues of a human body, at least part of said biodegradable material including a radioisotope, said biodegradable material and said radioisotope each being adapted to be absorbed into the human body.
Claim 16
Dependent Claim
11 words
The apparatus of claim 12 wherein the beta emitter is phosphorous-32.
References Cited (Backward Citations)
EP0292630A1
Cited
US5059166A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-08-17 | 2002-02-16 | 2002-08-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-08-17 | 2006-02-16 | 2006-08-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-08-17 | 2010-02-16 | 2010-08-18 | $7700.00 | Window Closed / Lapsed |