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US5749845A Expired / Lapsed US ⏱️ 0.0 years remaining

Delivering an agent to an organ

Assignee: CorTrak Medical Inc
•
Filing: 1995-01-25
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Granted: 1998-05-12
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Expires: 2015-01-25
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Abstract

Abstract A method of delivering an agent to an organ from the group consisting of a bladder or a uterus. The method utilizes a catheter having an inflatable portion. The inflatable portion of the catheter is inserted into the organ and is inflated so that it expands the organ. The agent is then delivered from the inflatable portion into the wall of the organ. The agent may be prevented from escaping the organ.

Inventors

  • 👤 Keith R. Hildebrand
  • 👤 J. Edward Shapland

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 01:42
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/20; A61N1/30; A61M; A61M31/00

Claims Analysis

Total Claims: 28
Claim 1
Independent Claim 95 words
A method of delivering an agent from a catheter having an inflatable portion to an organ from the group consisting of a bladder and a uterus, the organ having an inner surface and folds of tissue along the inner surface, the method comprising the steps of: (a) inserting the inflatable portion of the catheter into the organ; (b) inflating the inflatable portion so that it expands the organ and removes folds of tissue along the inner surface of the organ; and (c) delivering the agent from the inflatable portion into the wall of the organ.
Claim 2
Independent Claim 95 words
A method of delivering an agent from a catheter having an inflatable portion to an organ from the group consisting of a bladder and a uterus, the organ having an inner surface and folds of tissue along the inner surface, the method comprising the steps of: (a) inserting the inflatable portion of the catheter into the organ; (b) inflating the inflatable portion so that it expands the organ and removes folds of tissue along the inner surface of the organ; and (c) delivering the agent from the inflatable portion into the wall of the organ.
Claim 3
Dependent Claim 30 words
The method of claim 1 wherein the step of inflating the inflatable portion includes substantially conforming the inner surface of the organ wall to the shape of the inflatable portion.
Claim 4
Dependent Claim 51 words
The method of claim 1 wherein the catheter further includes a first electrode being inside the inflatable portion of the catheter and a second electrode being in contact with the patient's body, further wherein the step of delivering the agent includes supplying an electric current between the first and second electrodes.
Claim 5
Dependent Claim 33 words
The method of claim 3 comprising the additional step of placing the second electrode against the skin of the patient's body before the electric current is supplied between the first and second electrodes.
Claim 6
Dependent Claim 24 words
The method of claim 1 wherein the step of inflating the inflatable portion of the catheter includes injecting the agent into the inflatable portion.
Claim 7
Dependent Claim 41 words
The method of claim 5 wherein the inflatable portion of the catheter has an interior, further wherein the step of delivering the agent includes causing the agent to pass from the interior of the inflatable portion and into the organ wall.
Claim 8
Dependent Claim 44 words
The method of claim 1 wherein the inflatable portion of the catheter has a polymer matrix and the polymer matrix embodies a second agent, the method comprising the additional step of delivering the second agent from the polymer matrix and into the organ wall.
Claim 9
Dependent Claim 48 words
The method of claim 1 wherein the inflatable portion of the catheter has a polymer matrix and the polymer matrix embodies the agent, further wherein the step of delivering the agent includes causing the agent to be released from the polymer matrix and pass into the organ wall.
Claim 10
Dependent Claim 27 words
The method of claim 1 comprising the additional step of providing a layer of the agent between the inflatable portion of the catheter and the organ wall.
Claim 11
Dependent Claim 31 words
The method of claim 1 wherein the organ is a bladder and the method comprises the additional step of preventing substantially all of the agent from flowing into the patient's urethra.
Claim 12
Dependent Claim 70 words
The method of claim 10 wherein the catheter includes a blocking portion that is inflatable, further wherein the step of preventing substantially all of the agent from flowing into the patient's urethra includes the steps of: (a) inserting the blocking portion of the catheter into the urethra so that it is proximate the bladder; and (b) inflating the blocking portion so that it substantially blocks substantially all of the urethra.
Claim 13
Dependent Claim 27 words
The method of claim 1 wherein the organ is bladder and the method comprises the additional step of preventing substantially any urine from accumulating in the bladder.
Claim 14
Dependent Claim 34 words
The method of claim 12 wherein the step of preventing substantially any urine from accumulating in the bladder comprises blocking the urters so that substantially no urine can flow the bladder from the ureters.
Claim 15
Dependent Claim 31 words
The method of claim 1 wherein the organ is a bladder and the method comprises the additional step of draining urine from the bladder before the step of delivering the agent.
Claim 16
Dependent Claim 41 words
The method of claim 14 comprising the additional steps of: (a) deflating the inflatable portion of the catheter after the step of delivering the agent; and (b) repeating the steps of draining urine, inflating the inflatable portion, and delivering the agent.
Claim 17
Dependent Claim 31 words
The method of claim 1 wherein the organ is a uterus and the method comprises the additional step of preventing substantially all of the agent from flowing into the patient's vagina.
Claim 18
Dependent Claim 46 words
The method of claim 16 wherein the catheter includes a blocking portion, further wherein the step of preventing substantially all of the agent from flowing into the patient's vagina includes the step positioning the blocking portion so that it substantially blocks the opening of the cervix.
Claim 19
Dependent Claim 35 words
The method of claim 17 wherein the blocking portion is a cap that fits over the cervix and the step of positioning the blocking portion includes the step of positioning the cap over the cervix.
Claim 20
Dependent Claim 32 words
The method of claim 1 wherein the organ is a uterus and the method comprises the additional step of preventing substantially all of the agent from flowing into the patient's fallopian tubes.
Claim 21
Independent Claim 133 words
A method of delivering an agent from a catheter having an inflatable portion to a patient's bladder, the catheter including a first electrode inside the inflatable portion and a second electrode in contact with the patient's body, the method comprising the steps of: (a) inserting the inflatable portion of the catheter into the bladder; (b) inflating the inflatable portion so that it expands the bladder, thereby substantially conforming the inner surface of the bladder wall to the shape of the inflated inflatable portion; (c) preventing substantially all of the agent from flowing into the patient's urethra; (d) preventing substantially any urine from accumulating in the bladder; and (e) supplying an electric current between the first and second electrodes thereby delivering the agent from the inflatable portion and into the wall of the bladder.
Claim 22
Independent Claim 133 words
A method of delivering an agent from a catheter having an inflatable portion to a patient's bladder, the catheter including a first electrode inside the inflatable portion and a second electrode in contact with the patient's body, the method comprising the steps of: (a) inserting the inflatable portion of the catheter into the bladder; (b) inflating the inflatable portion so that it expands the bladder, thereby substantially conforming the inner surface of the bladder wall to the shape of the inflated inflatable portion; (c) preventing substantially all of the agent from flowing into the patient's urethra; (d) preventing substantially any urine from accumulating in the bladder; and (e) supplying an electric current between the first and second electrodes thereby delivering the agent from the inflatable portion and into the wall of the bladder.
Claim 23
Independent Claim 140 words
A method of delivering an agent from a catheter having an inflatable portion to a patient's bladder, the catheter including a first electrode inside the inflatable portion and a second electrode in contact with the patient's body, the method comprising the steps of: (a) inserting the inflatable portion of the catheter into the bladder; (b) injecting the agent into the inflatable portion so that the inflatable portion inflates and expands the bladder, thereby substantially conforming the inner surface of the bladder wall to the shape of the inflated inflatable portion; (c) preventing substantially all of the agent from flowing into the patient's urethra; (d) preventing substantially any urine from accumulating in the bladder; and (e) supplying an electric current between the first and second electrodes thereby delivering the agent from the inflatable portion and into the wall of the bladder.
Claim 24
Independent Claim 140 words
A method of delivering an agent from a catheter having an inflatable portion to a patient's bladder, the catheter including a first electrode inside the inflatable portion and a second electrode in contact with the patient's body, the method comprising the steps of: (a) inserting the inflatable portion of the catheter into the bladder; (b) injecting the agent into the inflatable portion so that the inflatable portion inflates and expands the bladder, thereby substantially conforming the inner surface of the bladder wall to the shape of the inflated inflatable portion; (c) preventing substantially all of the agent from flowing into the patient's urethra; (d) preventing substantially any urine from accumulating in the bladder; and (e) supplying an electric current between the first and second electrodes thereby delivering the agent from the inflatable portion and into the wall of the bladder.
Claim 25
Independent Claim 144 words
A method of delivering an agent from a catheter having an inflatable portion to a patient's uterus, the catheter including a first electrode inside the inflatable portion and a second electrode in contact with the patient's body, the method comprising the steps of: (a) inserting the inflatable portion of the catheter into the uterus; (b) injecting the agent into the inflatable portion so that the inflatable portion inflates and expands the uterus, thereby substantially conforming the inner surface of the uterus wall to the shape of the inflated inflatable portion; (c) preventing substantially all of the agent from flowing through the patient's cervix; (d) preventing substantially all of the agent from flowing into the patient's fallopian tubes; and (e) supplying an electric current between the first and second electrodes thereby delivering the agent from the inflatable portion and into the wall of the uterus.
Claim 26
Independent Claim 144 words
A method of delivering an agent from a catheter having an inflatable portion to a patient's uterus, the catheter including a first electrode inside the inflatable portion and a second electrode in contact with the patient's body, the method comprising the steps of: (a) inserting the inflatable portion of the catheter into the uterus; (b) injecting the agent into the inflatable portion so that the inflatable portion inflates and expands the uterus, thereby substantially conforming the inner surface of the uterus wall to the shape of the inflated inflatable portion; (c) preventing substantially all of the agent from flowing through the patient's cervix; (d) preventing substantially all of the agent from flowing into the patient's fallopian tubes; and (e) supplying an electric current between the first and second electrodes thereby delivering the agent from the inflatable portion and into the wall of the uterus.
Claim 27
Independent Claim 93 words
A method of delivering an agent from a catheter to a bladder, the catheter having an inflatable portion and a drainage lumen, the inflatable portion defining channels that extend from the ureters to the drainage lumen, the method comprising the steps of: (a) inserting the inflatable portion of the catheter into the organ; (b) inflating the inflatable portion so that it expands the organ; (c) delivering the agent from the inflatable portion into the wall of the organ; and (d) channeling substantially all of the urine from the ureters to the drainage lumen.
Claim 28
Independent Claim 93 words
A method of delivering an agent from a catheter to a bladder, the catheter having an inflatable portion and a drainage lumen, the inflatable portion defining channels that extend from the ureters to the drainage lumen, the method comprising the steps of: (a) inserting the inflatable portion of the catheter into the organ; (b) inflating the inflatable portion so that it expands the organ; (c) delivering the agent from the inflatable portion into the wall of the organ; and (d) channeling substantially all of the urine from the ureters to the drainage lumen.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2001-05-11 2001-11-10 2002-05-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2005-05-11 2005-11-10 2006-05-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2009-05-11 2009-11-10 2010-05-12 $7700.00 Window Closed / Lapsed

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