US5735885A
Expired / Lapsed
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Methods for implanting neural prosthetic for tinnitus
Assignee: University of Iowa Research Foundation
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Filing: 1996-02-06
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Granted: 1998-04-07
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Expires: 2016-02-06
Abstract
Abstract A method for implanting a neural prosthetic into a target zone of a patient's brain for reducing or eliminating the effects of tinnitus. The prosthetic includes a stimulation device for outputting processed electrical signals and an electrode which is arranged in the target zone having a plurality of electrical contacts. Each of the plurality of electrical contacts independently outputs electrical discharges in accordance with the electrical signals.
Inventors
- 👤 Matthew A. Howard, III
- 👤 Timothy A. McCulloch
- 👤 Carol A. Bauer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 06:52
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/142; A61M5/14244; A61M5/14276; A61B; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/148; A61F; A61F11/00; A61F5/00; A61F5/0003; A61F5/0013; A61F5/0026; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/05; A61N1/0526; A61N1/0529; A61N1/0531; A61N1/0539; A61N1/0541; A61N1/18; A61N1/32; A61N1/326; A61N1/36; A61N1/3605; A61N1/3606; A61N1/36082; A61N1/361; A61B2018/00315; A61B2018/00434; A61B2018/00571; A61B2018/00577; A61B2018/00636; A61B2018/00773; A61B2018/00839; A61B90/00; A61B90/10; A61F11/20; A61M2210/00; A61M2210/06; A61M2210/0693; A61M27/00; A61M27/002; A61M27/006; A61M5/1428; A61M5/168; A61M5/172; A61M5/1723
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
157 words
A method of implanting an electrode of a neural prosthetic apparatus into an internal target zone of a patient's brain, comprising the steps of: acquiring a three dimensional digital image of the patient's brain and storing said three dimensional digital image as a first data set in a memory of a computer; digitally subtracting data from said first data set to provide a second data set capable of being displayed as a modified three dimensional image depicting the orientation of the target zone of the patient's brain; displaying said modified three dimensional image; and inserting said electrode into said target zone using said modified three dimensional image as a guide, wherein said electrode comprises a plurality of electrical contacts, said prosthetic apparatus comprises a stimulation device for outputting electrical signals, each of said plurality of electrical contacts is electrically coupled to said stimulation device and is capable of outputting electrical discharges in accordance with said electrical signals.
Claim 2
Independent Claim
157 words
A method of implanting an electrode of a neural prosthetic apparatus into an internal target zone of a patient's brain, comprising the steps of: acquiring a three dimensional digital image of the patient's brain and storing said three dimensional digital image as a first data set in a memory of a computer; digitally subtracting data from said first data set to provide a second data set capable of being displayed as a modified three dimensional image depicting the orientation of the target zone of the patient's brain; displaying said modified three dimensional image; and inserting said electrode into said target zone using said modified three dimensional image as a guide, wherein said electrode comprises a plurality of electrical contacts, said prosthetic apparatus comprises a stimulation device for outputting electrical signals, each of said plurality of electrical contacts is electrically coupled to said stimulation device and is capable of outputting electrical discharges in accordance with said electrical signals.
Claim 3
Dependent Claim
44 words
The method as claimed in claim 1, further comprising the steps of: repeatedly outputting said electrical signals to said plurality of electrical contacts; and adjusting the orientation of said electrode in said auditory cortex as the patient describes effects of said repeatedly outputting step.
Claim 4
Dependent Claim
28 words
The method as claimed in claim 2, wherein said repeatedly outputting step comprises repeatedly outputting signals which cause said auditory cortex to be stimulated at geometrically separate locations.
Claim 5
Dependent Claim
24 words
The method as claimed in claim 2, wherein said repeatedly outputting step comprises repeatedly outputting signals of varying power at said geometrically separate locations.
Claim 6
Dependent Claim
60 words
The method according to claim 1, wherein said digitally subtracting step comprises subtracting data from said first data set to yield an image which shows one of an auditory cortex and a medial geniculate nucleus of a thalamus, and said inserting step comprises inserting said electrode into one of the auditory cortex and the medial geniculate nucleus of the thalamus.
Claim 7
Dependent Claim
34 words
The method according to claim 5, wherein said inserting step comprises inserting said electrode into the auditory cortex through a rigid introducer and arranging said electrode along the longitudinal direction of the auditory cortex.
Claim 8
Independent Claim
100 words
A method of implanting an electrode of a neural prosthetic apparatus into a target zone of a patient's brain, comprising the steps of: determining the location of the target zone within the patient's brain; inserting the electrode into the target zone, the electrode having a plurality of electrical contacts, wherein one or more of said plurality of electrical contacts is electrically coupled to a stimulation device; and outputting electrical signals from said stimulation device, said one or more electrical contacts is capable outputting electrical discharges and stimulating said target zone of the patient's brain in accordance with said electrical signals.
Claim 9
Independent Claim
100 words
A method of implanting an electrode of a neural prosthetic apparatus into a target zone of a patient's brain, comprising the steps of: determining the location of the target zone within the patient's brain; inserting the electrode into the target zone, the electrode having a plurality of electrical contacts, wherein one or more of said plurality of electrical contacts is electrically coupled to a stimulation device; and outputting electrical signals from said stimulation device, said one or more electrical contacts is capable outputting electrical discharges and stimulating said target zone of the patient's brain in accordance with said electrical signals.
Claim 10
Dependent Claim
83 words
The method of claim 7, wherein said outputting electrical signals step comprises outputting electrical signals from a chronic electrical stimulation device, said one or more of said plurality of electrical contacts is capable of outputting electrical discharges and stimulating said target zone of the patient's brain at geometrically separate locations in accordance with said electrical signals, and said stimulating said target zone of the patient's brain at said geometrically separate locations disrupts abnormal neural activity associated with tinnitus at said geometrically separate locations.
Claim 11
Dependent Claim
75 words
The method of claim 7, wherein said step of determining the location of the target zone of the patient's brain comprises: acquiring a three dimensional digital image of the patient's brain and storing said three dimensional digital image in a memory of a computer; digitally subtracting data from said three dimensional digital image to yield a modified three dimensional digital image which shows the location and orientation of the target zone of the patient's brain.
Claim 12
Dependent Claim
33 words
The method of claim 7, further comprising the step of: adjusting the orientation of the electrode within the target zone of the patient's brain according to the patient's response to said electrical discharges.
Claim 13
Dependent Claim
29 words
The method of claim 10, further comprising the step of: repeatedly outputting electrical discharges from the one or more electrical contacts to disrupt abnormal neural activity associated with tinnitus.
Claim 14
Dependent Claim
60 words
The method of claim 7, wherein said step of determining the location of the target zone within the patient's brain comprises determining the location of one of an auditory cortex and a medial geniculate nucleus of a thalamus, and said inserting step comprises inserting said electrode into one of the auditory cortex and the medial geniculate nucleus of the thalamus.
Claim 15
Dependent Claim
49 words
The method according to claim 7, wherein said outputting electrical signals step comprises independently outputting electrical discharges from one or more of said plurality of electrical contacts locations within the target zone of the patient's brain, each of said plurality of electrical contacts independently coupled to the stimulation device.
Claim 16
Independent Claim
97 words
A method of treating a tinnitus patient, comprising the steps of: obtaining an image of the patient's brain; modifying the image of the patient's brain to display an internal brain target zone; inserting an electrode into the target zone using the modified image as a guide, wherein said electrode has a plurality of electrical contacts for outputting electrical discharges; electrically coupling one or more of said plurality of electrical contacts to a stimulation device for outputting electrical signals; and outputting electrical signals from said stimulation device and outputting electrical discharges from said one or more electrical contacts.
Claim 17
Independent Claim
97 words
A method of treating a tinnitus patient, comprising the steps of: obtaining an image of the patient's brain; modifying the image of the patient's brain to display an internal brain target zone; inserting an electrode into the target zone using the modified image as a guide, wherein said electrode has a plurality of electrical contacts for outputting electrical discharges; electrically coupling one or more of said plurality of electrical contacts to a stimulation device for outputting electrical signals; and outputting electrical signals from said stimulation device and outputting electrical discharges from said one or more electrical contacts.
Claim 18
Dependent Claim
38 words
The method of claim 14, further comprising the steps of: adjusting the orientation of the electrode in the target zone according to the patient's response to said electrical discharges; and repeatedly outputting electrical discharges from said electrical contacts.
Claim 19
Dependent Claim
72 words
The method of claim 14, wherein said step of obtaining an image of the patient's brain comprises: acquiring a three dimensional digital image of the patient's brain and storing said three dimensional digital image in a memory of a computer; and digitally subtracting data from said three dimensional digital image to yield a modified three dimensional digital image which shows the location and orientation of the target zone of the patient's brain.
Claim 20
Dependent Claim
27 words
The method of claim 14, wherein said inserting step comprises inserting an electrode into one of an auditory cortex and a medial geniculate nucleus of a thalamus.
Claim 21
Dependent Claim
20 words
The method of claim 14, wherein said inserting step comprises inserting one of a rigid electrode and a flexible electrode.
Claim 22
Dependent Claim
33 words
The method of claim 14, wherein said inserting step comprises inserting the electrode through a rigid introducer into the auditory cortex and arranging said electrode along the longitudinal direction of the auditory cortex.
Claim 23
Dependent Claim
48 words
The method of claim 14, wherein said outputting electrical signals step comprises outputting electrical signals from a chronic electrical stimulation device, and said outputted electrical discharges cause stimulation of the target zone of the patient's brain at a plurality of spatially separate locations and disrupt abnormal neural activity.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-04-06 | 2001-10-06 | 2002-04-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-04-06 | 2005-10-06 | 2006-04-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-04-06 | 2009-10-06 | 2010-04-07 | $7700.00 | Window Closed / Lapsed |