← Back to Patent Explorer
US5721049A Expired / Lapsed US ⏱️ 0.0 years remaining

Composite materials using bone bioactive glass and ceramic fibers

Assignee: University of Pennsylvania
•
Filing: 1995-06-05
•
Granted: 1998-02-24
•
Expires: 2015-06-05
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract Composite materials formed from bone bioactive glass or ceramic fibers and structural fibers are disclosed. In preferred embodiments, a braid or mesh of interwoven bone bioactive glass or ceramic fibers and structural fibers is impregnated with a polymeric material to provide a composite of suitable biocompatibility and structural integrity. Most preferably, the mesh or braid is designed so that the bioactive fibers are concentrated at the surface of the implant to create a surface comprised of at least 30% bioactive material, thereby providing enhanced bone ingrowth. The interweaving between the bone bioactive glass or ceramic fibers and the core of structural fibers overcomes the problems found in prior composite systems where the bioactive material delaminates from the polymer. Preferred bioactive materials include calcium phosphate ceramics and preferred structural fibers include carbon fibers. Further preferred bioactive materials include aluminum oxide at greater than 0.2%, by mole. Improved prosthetic implants and methods of affixing an implant are thus also disclosed.

Inventors

  • 👤 Michele S. Marcolongo
  • 👤 Paul Ducheyne
  • 👤 Frank Ko
  • 👤 William LaCourse

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 14:53
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/3094; A61F2/30965; A61F2/32; A61F2/36; A61F2/3662; A61F2/367; A61L; A61L27/00; A61L27/02; A61L27/025; A61L27/10; A61L27/40; A61L27/42; A61L27/422; A61L27/44; A61L27/443; A61L27/446; C; C03; C03C; C03C13/00; D; D03; D03D; D03D15/00; D03D15/20; D03D15/242; D03D15/267; D03D15/275; D03D15/283; D03D15/50; D03D15/587; D03D9/00; A61F2002/30001; A61F2002/30108; A61F2002/30199; A61F2002/30289; A61F2/30767; A61F2/30771; A61F2002/3082; A61F2230/00; A61F2230/0063; A61F2230/0091; C03C2213/00; C03C2213/02; D10; D10B; D10B2101/00; D10B2101/02; D10B2101/06; D10B2101/08; D10B2101/10; D10B2101/12; D10B2331/00; D10B2331/02; D10B2331/021; D10B2401/00; D10B2401/04; D10B2401/041; D10B2401/06; D10B2401/061; D10B2401/063; D10B2509/00; Y; Y10; Y10T; Y10T428/00; Y10T428/249921; Y10T428/249924; Y10T428/24994; Y10T428/249949; Y10T428/29; Y10T428/2904; Y10T428/2907; Y10T428/2913; Y10T428/2922; Y10T428/2924; Y10T428/2929; Y10T428/2931; Y10T428/31504

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 44 words
A biocompatible composite of tows of bone bioactive fibers comprising at least 19% Na 2 O by mole and greater than 0.2% Al 2 O 3 by mole, said tows of bioactive fibers intermingled with tows of structural fibers in a nonbioabsorbable polymeric matrix.
Claim 2
Dependent Claim 44 words
A biocompatible composite of tows of bone bioactive fibers comprising at least 19% Na 2 O by mole and greater than 0.2% Al 2 O 3 by mole, said tows of bioactive fibers intermingled with tows of structural fibers in a nonbioabsorbable polymeric matrix.
Claim 3
Dependent Claim 40 words
The composite of claim 1, wherein the bone bioactive fibers are arranged in a predetermined distribution and a section of a surface of the composite to be affixed to bone is comprised of about 30% or more bone bioactive fibers.
Claim 4
Dependent Claim 13 words
The composite of claim 1 wherein the structural fiber is a carbon fiber.
Claim 5
Dependent Claim 20 words
The composite of claim 1 wherein the polymeric material is chosen from the group consisting of: polysulfone; PEEK; and PEKK.
Claim 6
Dependent Claim 35 words
The composite of claim 1, wherein the bone bioactive fibers comprise 40-60% SiO 2 , 19-30% Na 2 O, 10-21% CaO, 0-4% P 2 O 5 , and 0.2-1% Al 2 O 3 by mole.
Claim 7
Dependent Claim 35 words
The composite of claim 1, wherein the bone bioactive fibers comprise 45-55% SiO 2 , 19-30% Na 2 O, 15-20% CaO, 0-3% P 2 O 5 , and 0.2-1% Al 2 O 3 by mole.
Claim 8
Dependent Claim 23 words
The composite of claim 1, further comprising a modifier selected from the group consisting of K 2 O, MgO, and F 2 .
Claim 9
Dependent Claim 21 words
The composite of claim 1 wherein the bone bioactive fibers have a diameter of from about 5 to about 25 microns.

References Cited (Backward Citations)

US4131597A Cited
US4202055A Cited
US4239113A Cited
US4329743A Cited
US4411027A Cited
US4604097A Cited
US4604097B1 Cited
US4781183A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2001-02-23 2001-08-25 2002-02-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2005-02-23 2005-08-25 2006-02-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2009-02-23 2009-08-25 2010-02-24 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag