US5711960A
Expired / Lapsed
US
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Biocompatible implant material comprising a tri-axial or more three-dimensional fabric
Assignee: Takiron Co Ltd
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Filing: 1995-05-24
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Granted: 1998-01-27
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Expires: 2015-05-24
Abstract
Abstract This invention provides an implant material which has high mechanical strength and durability in three-dimensional directions and a function to synchronize with deformation characteristics of surrounding biological tissues, is capable of being penetrated by biological tissues into its fabric space, and does not cause foreign body reaction or can positively connect with biological tissues, so that it can be implanted in the living body for a prolonged period of time. It uses, as a base material, a biocompatible bulk structure of a three-dimensionally woven or knitted fabric of organic fibers or a composite fabric thereof, and its void ratio in the fabric is preferably set to 20 to 90 vol %. More preferably, the surface of organic fibers which constitute the bulk structure is biologically activated or inactivated.
Inventors
- 👤 Yasuo Shikinami
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:33
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/56; A61F; A61F2/00; A61F2/0063; A61F2/02; A61F2/28; A61F2/30; A61F2/30756; A61F2/3094; A61F2/30965; A61F2/0077; A61F2/30767; A61F2002/0068; A61F2002/30001; A61F2002/30003; A61F2002/30004; A61F2002/30009; A61F2002/3006; A61F2002/30062; A61F2002/30108; A61F2002/30199; A61F2002/30261; A61F2/30907; A61F2002/30909; A61F2002/30914; A61F2002/30915; A61F2002/3092; A61F2210/00; A61F2210/0004; A61F2230/00; A61F2230/0063; A61F2230/0082; A61F2250/00; A61F2250/0014; A61F2250/0028; A61F2310/00; A61F2310/00389; A61F2310/00592; A61F2310/00796; Y; Y10; Y10T; Y10T428/00; Y10T428/13; Y10T428/1352; Y10T428/1362; Y10T428/1369
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
38 words
An implant material which comprises, as a base material, a biocompatible bulk structure of a tri-axial or more three-dimensionally woven fabric of organic fibers, a tri-axial or more three-dimensionally knitted fabric of organic fibers or a combination thereof.
Claim 2
Dependent Claim
38 words
An implant material which comprises, as a base material, a biocompatible bulk structure of a tri-axial or more three-dimensionally woven fabric of organic fibers, a tri-axial or more three-dimensionally knitted fabric of organic fibers or a combination thereof.
Claim 3
Dependent Claim
29 words
The implant material according to claim 1, wherein a void ratio in the fabric of the bulk structure is in the range of from 20 to 90 vol %.
Claim 4
Dependent Claim
31 words
The implant material according to claim 1 or 2, wherein the organic fibers which constitute the bulk structure are bioinert fibers or fibers having a surface coated with a bioinert polymer.
Claim 5
Dependent Claim
21 words
The implant material according to claim 1, wherein the organic fibers which constitute the bulk structure are bioactive or bioaffinitive fibers.
Claim 6
Dependent Claim
22 words
The implant material according to claim 1, wherein the organic fibers which constitute the bulk structure are biologically degradable and absorbable fibers.
Claim 7
Dependent Claim
18 words
The implant material according to claim 3, wherein the bulk structure has a surface that is biologically activated.
Claim 8
Dependent Claim
32 words
The implant material according to claim 6, wherein the bulk structure has a surface that is biologically activated by grafting it with a monomer or an oligomer having an organic phosphate group.
Claim 9
Dependent Claim
32 words
The implant material according to claim 6, wherein the bulk structure has a surface that is biologically activated by coating it with a biologically degradable and absorbable polymer containing a bioactive substance.
Claim 10
Dependent Claim
41 words
The implant material according to claim 6, wherein the bulk structure has a surface that is biologically activated by coating it with a polymer containing a bioactive substance and scraping off the surface of said polymer to expose the bioactive substance.
Claim 11
Dependent Claim
31 words
The implant material according to claim 8 or 9, wherein said bioactive substance is at least one substance selected from the group consisting of bioglass, ceravital, hydroxyapatite and AW glass ceramics.
Claim 12
Dependent Claim
27 words
The implant material according to claim 6, wherein the bulk structure has a surface that is biologically activated by immobilizing a natural biomaterial to the surface thereof.
Claim 13
Dependent Claim
32 words
The implant material according to claim 11, wherein said natural biomaterial is at least one substance selected from the group consisting of collagen, gelatin, fibronectin, hyaluronic acid, thrombomodulin, hydroxyapatite, urokinase and heparin.
Claim 14
Dependent Claim
28 words
The implant material according to claim 3, wherein the bulk structure has a surface that is biologically inactivated by immobilizing a highly hydrophilic hydrogel to the surface thereof.
Claim 15
Dependent Claim
47 words
The implant material according to claim 13, wherein said highly hydrophilic hydrogel is at least one gel selected from the group consisting of gelatin, methylcellulose, hydroxypropylmethylcellulose, alginic acid, agar, carrageenan, proteoglycan, hyaluronic acid, collagen, fibrin, casein, polyvinyl alcohol gels, polyethylene oxide gels and polyhydroxymethacrylic acid base gels.
Claim 16
Dependent Claim
32 words
The implant material according to any one of claims 1 to 14, wherein a matrix of the same or different organic fibers is filled in a fabric space of the bulk structure.
Claim 17
Dependent Claim
13 words
The implant material according to claim 15, wherein the bulk structure is compression-molded.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 2001-01-26 | 2001-07-28 | 2002-01-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-01-26 | 2005-07-28 | 2006-01-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-01-26 | 2009-07-28 | 2010-01-27 | $7700.00 | Window Closed / Lapsed |