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US5697975A Expired / Lapsed US ⏱️ 0.0 years remaining

Human cerebral cortex neural prosthetic for tinnitus

Assignee: University of Iowa Research Foundation
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Filing: 1994-11-01
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Granted: 1997-12-16
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Expires: 2014-11-01
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Abstract

Abstract A neural prosthetic device for reducing or eliminating the effects of tinnitus is inserted into a tinnitus patient's primary auditory cortex (or thalamus). The prosthetic device includes a stimulation device for outputting processed electrical signals and an electrode arranged in the primary auditory cortex having a plurality of electrical contacts. Each of the plurality of electrical contacts independently outputs electrical discharges in accordance with the electrical signals. In another embodiment, a catheter is inserted into the tinnitus patient's primary auditory cortex or thalamus. The catheter microinfuses drugs which suppress or eliminate abnormal neural activity into disperse geometric locations in the cortex or thalamus, thereby reducing or eliminating the effects of the patient's tinnitus.

Inventors

  • 👤 Matthew A. Howard, III
  • 👤 Timothy M. McCulloch
  • 👤 Carol A. Bauer

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 13:37
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/142; A61M5/14244; A61M5/14276; A61B; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/148; A61F; A61F11/00; A61F5/00; A61F5/0003; A61F5/0013; A61F5/0026; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/05; A61N1/0526; A61N1/0529; A61N1/0531; A61N1/0539; A61N1/0541; A61N1/18; A61N1/32; A61N1/326; A61N1/36; A61N1/3605; A61N1/3606; A61N1/36082; A61N1/361; A61B2018/00315; A61B2018/00434; A61B2018/00571; A61B2018/00577; A61B2018/00636; A61B2018/00773; A61B2018/00839; A61B90/00; A61B90/10; A61F11/20; A61M2210/00; A61M2210/06; A61M2210/0693; A61M27/00; A61M27/002; A61M27/006; A61M5/1428; A61M5/168; A61M5/172; A61M5/1723

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 96 words
A neural prosthetic apparatus for treatment of a patient with tinnitus, comprising: a stimulation device for outputting one or more electrical signals; an electrode for tonotopic arrangement along the patient's primary auditory cortex having a plurality of electrical contacts approximately uniformly arranged along said electrode from about 50 to about 150 micrometers apart, each of said plurality of electrical contacts independently outputting electrical discharges in accordance with said electrical signals; and, electrical coupling means for electrically coupling said electrical contacts to said stimulation device, wherein said neural prosthetic apparatus effectively alleviates the tinnitus of said patient.
Claim 2
Dependent Claim 96 words
A neural prosthetic apparatus for treatment of a patient with tinnitus, comprising: a stimulation device for outputting one or more electrical signals; an electrode for tonotopic arrangement along the patient's primary auditory cortex having a plurality of electrical contacts approximately uniformly arranged along said electrode from about 50 to about 150 micrometers apart, each of said plurality of electrical contacts independently outputting electrical discharges in accordance with said electrical signals; and, electrical coupling means for electrically coupling said electrical contacts to said stimulation device, wherein said neural prosthetic apparatus effectively alleviates the tinnitus of said patient.
Claim 3
Dependent Claim 107 words
A neural prosthetic apparatus for the treatment of a patient with tinnitus, comprising: a stimulation device for outputting electrical signals: an electrode, for tenotopic arrangement in a patient's cortex or thalamus, said electrode having a plurality of electrical contacts spaced from about 10 micrometers to about 2 millimeters apart and electrically coupled to said stimulation device, and an electrical coupling means for electrically coupling said plurality of electrical contacts to said stimulation device, wherein one or more of said plurality of electrical contacts outputs electrical discharges that are in accordance with said electrical signals, and wherein said neural prosthetic apparatus effectively alleviates the tinnitus of said patient.
Claim 4
Dependent Claim 107 words
A neural prosthetic apparatus for the treatment of a patient with tinnitus, comprising: a stimulation device for outputting electrical signals: an electrode, for tenotopic arrangement in a patient's cortex or thalamus, said electrode having a plurality of electrical contacts spaced from about 10 micrometers to about 2 millimeters apart and electrically coupled to said stimulation device, and an electrical coupling means for electrically coupling said plurality of electrical contacts to said stimulation device, wherein one or more of said plurality of electrical contacts outputs electrical discharges that are in accordance with said electrical signals, and wherein said neural prosthetic apparatus effectively alleviates the tinnitus of said patient.
Claim 5
Dependent Claim 48 words
The neural prosthetic apparatus as claimed in claim 2, wherein said electrode is for arrangement in said cortex and said plurality of electrical contacts are arranged on said electrode such that each of said plurality of electrical contacts is capable of stimulating geometrically separate locations of said cortex.
Claim 6
Dependent Claim 20 words
The neural prosthetic apparatus as claimed in claim 2, further comprising a stopping piece for holding said electrode in place.
Claim 7
Dependent Claim 14 words
The neural prosthetic apparatus as claimed in claim 2, wherein said electrode is cylindrical.
Claim 8
Dependent Claim 20 words
The neural prosthetic apparatus as claimed in claim 2, wherein said electrical contacts are approximately uniformly arranged along said electrode.
Claim 9
Dependent Claim 21 words
The neural prosthetic apparatus as claimed in claim 2, wherein said electrical contacts are spaced approximately 50 to 150 micrometers apart.
Claim 10
Dependent Claim 55 words
The neural prosthetic apparatus as claimed in claim 1, further comprising: at least one additional electrode for tonotopic arrangement in said cortex or thalamus, said at least one additional electrode having an additional plurality of electrical contacts electrically coupled to said stimulation device, each of said additional plurality of electrical contacts outputting additional electrical signals.
Claim 11
Dependent Claim 29 words
The neural prosthetic apparatus as claimed in claim 2, wherein said stimulation device can adjustably output electrical signals with sufficient electrical power to eliminate effects of the patient's tinnitus.
Claim 12
Dependent Claim 28 words
The neural prosthetic apparatus as claimed in claim 2, wherein said electrical contacts can further sense electrical discharges, occurring in said one of the patient's cortex and thalamus.

References Cited (Backward Citations)

US4357497A Cited
EP0259906A2 Cited
US5000194A Cited
US5271397A Cited
US5496369A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2000-12-15 2001-06-16 2001-12-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2004-12-15 2005-06-16 2005-12-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2008-12-15 2009-06-16 2009-12-16 $7700.00 Window Closed / Lapsed

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