Coupling systems for saftey cannula

Claim 2

A coupling system for transferring a medicament from a cartridge to a pre-slit injection site wherein said pre-slit injection site comprises: a cylindrical housing having a first end and a second end; internal male luer threads located in said cylindrical housing adjacent to said second end to receive and engage a catheter having female luer threads thereon; a hollow cylindrical funnel-shaped fluid flow member providing a sterile fluid flow coupling when said catheter is engaged with said pre-slit injection site; said hollow cylindrical funnel-shaped fluid flow member being a female member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said cylindrical funnel-shaped fluid flow member; and a proximal cylindrical end portion; and a resealable septum located at the first end of said housing to seal said pre-slit injection site when said pre-slit injection site is not engaged by said catheter; wherein said coupling system comprises: a hub having a proximal and distal end and a flow channel located centrally therein, said flow channel comprising: a needle cannula having a sharp end at the proximal end of the hub; and a blunt cannula at the distal end of the hub; said blunt cannula being a male member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said blunt cannula; and a proximal cylindrical end portion; said male member is designed to engage said female member when the coupling system is connected to the injection site; said hub comprising: a first sleeve located on the proximal end of the hub and designed to engage a closure on a cartridge; a second sleeve located on the distal end of the hub having internal threads thereon to engage said catheter connected to said pre-slit injection site; and a middle portion integral with and connecting the sleeves on the proximal and distal ends of the hub; said first sleeve covering in a spaced relationship and extending beyond the sharp end of said needle cannula.

Claim 3

A coupling system for transferring a medicament from a cartridge to a pre-slit injection site wherein said pre-slit injection site comprises: a cylindrical housing having a first end and a second end; internal male luer threads located in said cylindrical housing adjacent to said second end to receive and engage a catheter having female luer threads thereon; a hollow cylindrical funnel-shaped fluid flow member providing a sterile fluid flow coupling when said catheter is engaged with said pre-slit injection site; said hollow cylindrical funnel-shaped fluid flow member being a female member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said cylindrical funnel-shaped fluid flow member; and a proximal cylindrical end portion; and a resealable septum located at the first end of said housing to seal said pre-slit injection site when said pre-slit injection site is not engaged by said catheter; wherein said coupling system in combination with a cartridge comprises: a cartridge, comprising a hollow body prefilled with a medicament having a sealed diaphragm on the distal end thereof and a piston axially and reciprocally slideable through the interior of said body; and a coupling system for transferring said medicament from said cartridge to the pre-slit injection site, said coupling system comprising: a hub having a proximal and distal end and a flow channel located centrally therein, said flow channel comprising: a needle cannnla having a sharp end at the proximal end of the hub; and a blunt cannula at the distal end of the hub; said blunt cannula being a male member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said blunt cannula; and a proximal cylindrical end portion; said male member is designed to engage said female member when the coupling system is connected to the injection site; said hub comprises: a first sleeve located on the proximal end of the hub and designed to engage a closure on said medicament-containing cartridge; a second sleeve located on the distal end of the hub having internal threads thereon to engage said catheter connected to said pre-slit injection site; and a middle portion integral with and connecting the sleeves on the proximal and distal ends of the hub; said first sleeve covering in a spaced relationship and extending beyond the sharp end of said needle cannula to prevent accidental needle strike.

Claim 4

A coupling system for transferring a medicament from a cartridge to a pre-slit injection site wherein said pre-slit injection site comprises: a cylindrical housing having a first end and a second end; internal male luer threads located in said cylindrical housing adjacent to said second end to receive and engage a catheter having female luer threads thereon; a hollow cylindrical funnel-shaped fluid flow member providing a sterile fluid flow coupling when said catheter is engaged with said pre-slit injection site; said hollow cylindrical funnel-shaped fluid flow member being a female member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said cylindrical funnel-shaped fluid flow member; and a proximal cylindrical end portion; and a resealable septum located at the first end of said housing to seal said pre-slit injection site when said pre-slit injection site is not engaged by said catheter; wherein said coupling system in combination with a cartridge comprises: a cartridge, comprising a hollow body prefilled with a medicament having a sealed diaphragm on the distal end thereof and a piston axially and reciprocally slideable through the interior of said body; and a coupling system for transferring said medicament from said cartridge to the pre-slit injection site, said coupling system comprising: a hub having a proximal and distal end and a flow channel located centrally therein, said flow channel comprising: a needle cannnla having a sharp end at the proximal end of the hub; and a blunt cannula at the distal end of the hub; said blunt cannula being a male member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said blunt cannula; and a proximal cylindrical end portion; said male member is designed to engage said female member when the coupling system is connected to the injection site; said hub comprises: a first sleeve located on the proximal end of the hub and designed to engage a closure on said medicament-containing cartridge; a second sleeve located on the distal end of the hub having internal threads thereon to engage said catheter connected to said pre-slit injection site; and a middle portion integral with and connecting the sleeves on the proximal and distal ends of the hub; said first sleeve covering in a spaced relationship and extending beyond the sharp end of said needle cannula to prevent accidental needle strike.

Claim 5

A coupling system for transferring a medicament form a cartridge to a pre-slit injection site in combination with a cartridge and holder assembly, the combination comprising: (a) a pre-slit injection site; (b) a cartridge in a cartridge holder; and (c) a coupling system; wherein said pre-slit injection site comprises: a cylindrical housing having a first end and a second end; internal male luer threads located in said cylindrical housing adjacent to said second end to receive and engage a catheter having female luer threads thereon; a hollow cylindrical funnel-shaped fluid flow member providing a sterile fluid flow coupling when said catheter is engaged with said pre-slit injection site; said hollow cylindrical funnel-shaped fluid flow member being a female member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said cylindrical funnel-shaped fluid flow member; and a proximal cylindrical end portion; and a resealable septum located at the first end of said housing to seal said pre-slit injection site when said pre-slit site is not engaged by said catheter; wherein said cartridge comprises: a hollow body prefilled with a medicament having a sealed diaphragm on the distal end thereof and a piston axially and reciprocally slideable through the interior of said body; and said cartridge holder comprises a frame, a damp and a plunger element containing a piston stem; said cartridge loaded into the frame of said cartridge holder; and wherein said coupling system for transferring said medicament from said cartridge to said pre-slit injection site comprises: a hub having a flow channel located centrally therein, said flow channel comprising: a needle cannula having a sharp end at the proximal end of the hub; and a blunt cannula at the distal end of the hub; said blunt cannula being a male member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said blunt cannula; and a proximal cylindrical end portion; said male member is designed to engage said female member when the coupling system is connected to the injection site; said hub comprising: a first sleeve located on the proximal end of the hub and designed to engage a closure on a cartridge; a second sleeve located on the distal end of the hub having internal threads thereon to engage said catheter connected to said pre-slit injection site; and a middle portion integral with and connecting the sleeves on the proximal and distal ends of the hub; said first sleeve covering in a spaced relationship and extending beyond the sharp end of said needle cannula to prevent accidental needle strikes, wherein said cartridge can be advanced distally through said holder by rotating said clamp such that the proximal end of said needle cannula penetrates said diaphragm, and said piston stem can be connected to said piston and actuated to drive said piston through said cartridge and expulse the fluid contents of said cartridge through said fluid flow channel into an injection site.

Claim 6

A coupling system for transferring a medicament form a cartridge to a pre-slit injection site in combination with a cartridge and holder assembly, the combination comprising: (a) a pre-slit injection site; (b) a cartridge in a cartridge holder; and (c) a coupling system; wherein said pre-slit injection site comprises: a cylindrical housing having a first end and a second end; internal male luer threads located in said cylindrical housing adjacent to said second end to receive and engage a catheter having female luer threads thereon; a hollow cylindrical funnel-shaped fluid flow member providing a sterile fluid flow coupling when said catheter is engaged with said pre-slit injection site; said hollow cylindrical funnel-shaped fluid flow member being a female member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said cylindrical funnel-shaped fluid flow member; and a proximal cylindrical end portion; and a resealable septum located at the first end of said housing to seal said pre-slit injection site when said pre-slit site is not engaged by said catheter; wherein said cartridge comprises: a hollow body prefilled with a medicament having a sealed diaphragm on the distal end thereof and a piston axially and reciprocally slideable through the interior of said body; and said cartridge holder comprises a frame, a damp and a plunger element containing a piston stem; said cartridge loaded into the frame of said cartridge holder; and wherein said coupling system for transferring said medicament from said cartridge to said pre-slit injection site comprises: a hub having a flow channel located centrally therein, said flow channel comprising: a needle cannula having a sharp end at the proximal end of the hub; and a blunt cannula at the distal end of the hub; said blunt cannula being a male member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said blunt cannula; and a proximal cylindrical end portion; said male member is designed to engage said female member when the coupling system is connected to the injection site; said hub comprising: a first sleeve located on the proximal end of the hub and designed to engage a closure on a cartridge; a second sleeve located on the distal end of the hub having internal threads thereon to engage said catheter connected to said pre-slit injection site; and a middle portion integral with and connecting the sleeves on the proximal and distal ends of the hub; said first sleeve covering in a spaced relationship and extending beyond the sharp end of said needle cannula to prevent accidental needle strikes, wherein said cartridge can be advanced distally through said holder by rotating said clamp such that the proximal end of said needle cannula penetrates said diaphragm, and said piston stem can be connected to said piston and actuated to drive said piston through said cartridge and expulse the fluid contents of said cartridge through said fluid flow channel into an injection site.

Claim 7

A coupling system for transferring a medicament from a cartridge to a pre-slit injection site wherein said pre-slit injection site comprises: a cylindrical housing having a first end and a second end; internal male luer threads located in said cylindrical housing adjacent to said second end to receive and engage a catheter having female luer threads thereon; a hollow cylindrical funnel-shaped fluid flow member providing a sterile fluid flow coupling when said catheter is engaged with said pre-slit injection site; said hollow cylindrical funnel-shaped fluid flow member being a female member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said cylindrical funnel-shaped fluid flow member; and a proximal cylindrical end portion; and a resealable septum located at the first end of said housing to seal said pre-slit injection site when said pre-slit site is not engaged by said catheter; wherein said coupling system comprises: a hub having a proximal and distal end and a flow channel located centrally therein, said flow channel comprising: a needle cannula having a sharp end at the proximal end of the hub; and a blunt cannula at the distal end of the hub; said blunt cannula being a male member comprising: a distal cylindrical end portion having a retention button thereon; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said blunt cannula; and a proximal cylindrical end portion; said male member is designed to engage said female member when the coupling system is connected to the injection site; said hub comprising: a first sleeve located on the proximal end of the hub and designed to engage a closure on a cartridge; a second sleeve located on the distal end of the hub having internal threads thereon to engage said catheter connected to said pre-slit injection site; and a middle portion integral with and connecting the sleeves on the proximal and distal ends of the hub; said first sleeve covering in a spaced relationship and extending beyond the sharp end of said needle cannula.

Claim 8

A coupling system for transferring a medicament from a cartridge to a pre-slit injection site wherein said pre-slit injection site comprises: a cylindrical housing having a first end and a second end; internal male luer threads located in said cylindrical housing adjacent to said second end to receive and engage a catheter having female luer threads thereon; a hollow cylindrical funnel-shaped fluid flow member providing a sterile fluid flow coupling when said catheter is engaged with said pre-slit injection site; said hollow cylindrical funnel-shaped fluid flow member being a female member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said cylindrical funnel-shaped fluid flow member; and a proximal cylindrical end portion; and a resealable septum located at the first end of said housing to seal said pre-slit injection site when said pre-slit site is not engaged by said catheter; wherein said coupling system comprises: a hub having a proximal and distal end and a flow channel located centrally therein, said flow channel comprising: a needle cannula having a sharp end at the proximal end of the hub; and a blunt cannula at the distal end of the hub; said blunt cannula being a male member comprising: a distal cylindrical end portion having a retention button thereon; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said blunt cannula; and a proximal cylindrical end portion; said male member is designed to engage said female member when the coupling system is connected to the injection site; said hub comprising: a first sleeve located on the proximal end of the hub and designed to engage a closure on a cartridge; a second sleeve located on the distal end of the hub having internal threads thereon to engage said catheter connected to said pre-slit injection site; and a middle portion integral with and connecting the sleeves on the proximal and distal ends of the hub; said first sleeve covering in a spaced relationship and extending beyond the sharp end of said needle cannula.

Claim 9

A coupling system for transferring a medicament from a cartridge to a pre-slit injection site wherein said pre-slit injection site comprises: a cylindrical housing having a first end and a second end; internal male luer threads located in said cylindrical housing adjacent to said second end to receive and engage a catheter having female luer threads thereon; a hollow cylindrical funnel-shaped fluid flow member providing a sterile fluid flow coupling when said catheter is engaged with said pre-slit injection site; said hollow cylindrical funnel-shaped fluid flow member being a female member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said cylindrical funnel-shaped fluid flow member; and a proximal cylindrical end portion; and a resealable septum located at the first end of said housing to seal said pre-slit injection site when said pre-slit injection site is not engaged by said catheter; wherein said coupling system in combination with a cartridge comprises: a cartridge, comprising a hollow body prefilled with a medicament having a sealed diaphragm on the distal end thereof and a piston axially and reciprocally slideable through the interior of said body; and a coupling system for transferring said medicament from said cartridge to the pre-slit injection site, said coupling system comprising: a hub having a proximal and distal end and a flow channel located centrally therein, said flow channel comprising: a needle cannula having a sharp end at the proximal end of the hub; and a blunt cannula at the distal end of the hub; said blunt cannula being a male member comprising: a distal cylindrical end portion having a retention button thereon; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said blunt cannula; and a proximal cylindrical end portion; said male member is designed to engage said female member when the coupling system is connected to the injection site; said hub comprises: a first sleeve located on the proximal end of the hub and designed to engage a closure on said medicament-containing cartridge; a second sleeve located on the distal end of the hub having internal threads thereon to engage said catheter connected to said pre-slit injection site; and a middle portion integral with and connecting the sleeves on the proximal and distal ends of the hub; said first sleeve covering in a spaced relationship and extending beyond the sharp end of said needle cannula to prevent accidental needle strike.

Claim 10

A coupling system for transferring a medicament from a cartridge to a pre-slit injection site wherein said pre-slit injection site comprises: a cylindrical housing having a first end and a second end; internal male luer threads located in said cylindrical housing adjacent to said second end to receive and engage a catheter having female luer threads thereon; a hollow cylindrical funnel-shaped fluid flow member providing a sterile fluid flow coupling when said catheter is engaged with said pre-slit injection site; said hollow cylindrical funnel-shaped fluid flow member being a female member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said cylindrical funnel-shaped fluid flow member; and a proximal cylindrical end portion; and a resealable septum located at the first end of said housing to seal said pre-slit injection site when said pre-slit injection site is not engaged by said catheter; wherein said coupling system in combination with a cartridge comprises: a cartridge, comprising a hollow body prefilled with a medicament having a sealed diaphragm on the distal end thereof and a piston axially and reciprocally slideable through the interior of said body; and a coupling system for transferring said medicament from said cartridge to the pre-slit injection site, said coupling system comprising: a hub having a proximal and distal end and a flow channel located centrally therein, said flow channel comprising: a needle cannula having a sharp end at the proximal end of the hub; and a blunt cannula at the distal end of the hub; said blunt cannula being a male member comprising: a distal cylindrical end portion having a retention button thereon; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said blunt cannula; and a proximal cylindrical end portion; said male member is designed to engage said female member when the coupling system is connected to the injection site; said hub comprises: a first sleeve located on the proximal end of the hub and designed to engage a closure on said medicament-containing cartridge; a second sleeve located on the distal end of the hub having internal threads thereon to engage said catheter connected to said pre-slit injection site; and a middle portion integral with and connecting the sleeves on the proximal and distal ends of the hub; said first sleeve covering in a spaced relationship and extending beyond the sharp end of said needle cannula to prevent accidental needle strike.

Claim 11

A coupling system for transferring a medicament from a cartridge to a pre-slit injection site in combination with a cartridge and holder assembly, the combination comprising: (a) a pre-slit injection site; (b) a cartridge in a cartridge holder; and (c) a coupling system; wherein said pre-slit injection site comprises: a cylindrical housing having a first end and a second end; internal male luer threads located in said cylindrical housing adjacent to said second end to receive and engage a catheter having female luer threads thereon; a hollow cylindrical funnel-shaped fluid flow member providing a sterile fluid flow coupling when said catheter is engaged with said pre-slit injection site; said hollow cylindrical funnel-shaped fluid flow member being a female member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said cylindrical funnel-shaped fluid flow member; and a proximal cylindrical end portion; and a resealable septum located at the first end of said housing to seal said pre-slit injection site when said pre-slit site is not engaged by said catheter; wherein said cartridge comprises: a hollow body prefilled with a medicament having a sealed diaphragm on the distal end thereof and a piston axially and reciprocally slideable through the interior of said body; and said cartridge holder comprises a frame, a clamp and a plunger element containing a piston stem; said cartridge loaded into the frame of said cartridge holder; and wherein said coupling system for transferring said medicament from said cartridge to said pre-slit injection site comprises: a hub having a flow channel located centrally therein, said flow channel comprising: a needle cannula having a sharp end at the proximal end of the hub; and a blunt cannula at the distal end of the hub; said blunt cannula being a male member comprising: a distal cylindrical end portion having a retention button thereon; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said blunt cannula; and a proximal cylindrical end portion; said male member is designed to engage said female member when the coupling system is connected to the injection site; said hub comprising: a first sleeve located on the proximal end of the hub and designed to engage a closure on a cartridge; a second sleeve located on the distal end of the hub having internal threads thereon to engage said catheter connected to said pre-slit injection site; and a middle portion integral with and connecting the sleeves on the proximal and distal ends of the hub; said first sleeve covering in a spaced relationship and extending beyond the sharp end of said needle cannula to prevent accidental needle strikes, wherein said cartridge can be advanced distally through said holder by rotating said clamp such that the proximal end of said needle cannula penetrates said diaphragm, and said piston stem can be connected to said piston and actuated to drive said piston through said cartridge and expulse the fluid contents of said cartridge through said fluid flow channel into an injection site.

Claim 12

A coupling system for transferring a medicament from a cartridge to a pre-slit injection site in combination with a cartridge and holder assembly, the combination comprising: (a) a pre-slit injection site; (b) a cartridge in a cartridge holder; and (c) a coupling system; wherein said pre-slit injection site comprises: a cylindrical housing having a first end and a second end; internal male luer threads located in said cylindrical housing adjacent to said second end to receive and engage a catheter having female luer threads thereon; a hollow cylindrical funnel-shaped fluid flow member providing a sterile fluid flow coupling when said catheter is engaged with said pre-slit injection site; said hollow cylindrical funnel-shaped fluid flow member being a female member comprising: a distal cylindrical end portion; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said cylindrical funnel-shaped fluid flow member; and a proximal cylindrical end portion; and a resealable septum located at the first end of said housing to seal said pre-slit injection site when said pre-slit site is not engaged by said catheter; wherein said cartridge comprises: a hollow body prefilled with a medicament having a sealed diaphragm on the distal end thereof and a piston axially and reciprocally slideable through the interior of said body; and said cartridge holder comprises a frame, a clamp and a plunger element containing a piston stem; said cartridge loaded into the frame of said cartridge holder; and wherein said coupling system for transferring said medicament from said cartridge to said pre-slit injection site comprises: a hub having a flow channel located centrally therein, said flow channel comprising: a needle cannula having a sharp end at the proximal end of the hub; and a blunt cannula at the distal end of the hub; said blunt cannula being a male member comprising: a distal cylindrical end portion having a retention button thereon; a middle tapered portion having a taper angle of from about 2° to about 20° to the longitudinal axis of said blunt cannula; and a proximal cylindrical end portion; said male member is designed to engage said female member when the coupling system is connected to the injection site; said hub comprising: a first sleeve located on the proximal end of the hub and designed to engage a closure on a cartridge; a second sleeve located on the distal end of the hub having internal threads thereon to engage said catheter connected to said pre-slit injection site; and a middle portion integral with and connecting the sleeves on the proximal and distal ends of the hub; said first sleeve covering in a spaced relationship and extending beyond the sharp end of said needle cannula to prevent accidental needle strikes, wherein said cartridge can be advanced distally through said holder by rotating said clamp such that the proximal end of said needle cannula penetrates said diaphragm, and said piston stem can be connected to said piston and actuated to drive said piston through said cartridge and expulse the fluid contents of said cartridge through said fluid flow channel into an injection site.