US5653233A
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Method and apparatus for improved temporal resolution in dynamic MRI
Assignee: Leland Stanford Junior University
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Filing: 1995-08-11
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Granted: 1997-08-05
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Expires: 2015-08-11
Abstract
Abstract Temporal resolution in dynamic magnetic resonance imaging is obtained by establishing a representation of static material in the field of view by averaging all signal acquisitions for a full field of view, and Fourier transforming the averaged data to yield an averaged image. The known dynamic portion of the image is set to zero to yield an image restricted to the static portion of the image. The averaged static portion is then inverse transformed to generate a synthetic MR raw data set that is an estimate of the data that would be collected if the object consisted only of the static material. The synthetic data are subtracted from the MR data for each view to eliminate the data for static material. The resulting data then represents the dynamic material which can be individually reconstructed.
Inventors
- 👤 Norbert J. Pelc
- 👤 Jill O. Fredrickson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 13:44
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/54; G01R33/56; G01R33/561; G01R33/4818; G01R33/4824; G01R33/563; G01R33/56308
Claims Analysis
Total Claims: 28
Claim 1
Independent Claim
127 words
A method for magnetic resonance (MR) imaging of an object which occupies a full field of view and within which a portion exhibits time varying signal, said dynamic portion occupying substantially only a portion of the full field of view, comprising the steps of: a) obtaining MR data for a plurality of time frames, each time frame composed of subframes, b) combining the data from multiple time frames to obtain data representative of an average image, c) using said data representing an average image to obtain data representing the static portion of the object and d) using the data from the static portion obtained in step c) and the data from one subframe to produce an image of the dynamic portion of the object during said subframe.
Claim 2
Independent Claim
127 words
A method for magnetic resonance (MR) imaging of an object which occupies a full field of view and within which a portion exhibits time varying signal, said dynamic portion occupying substantially only a portion of the full field of view, comprising the steps of: a) obtaining MR data for a plurality of time frames, each time frame composed of subframes, b) combining the data from multiple time frames to obtain data representative of an average image, c) using said data representing an average image to obtain data representing the static portion of the object and d) using the data from the static portion obtained in step c) and the data from one subframe to produce an image of the dynamic portion of the object during said subframe.
Claim 3
Dependent Claim
31 words
The method as defined by claim 1 wherein step c) includes a reverse Fourier transform of said image to k-space, and step d) includes Fourier transforming k-space data to image data.
Claim 4
Dependent Claim
21 words
The method as defined by claim 2 wherein said magnetic resonance imaging is segmented k-space imaging using spin warp phase encoding.
Claim 5
Dependent Claim
19 words
The method as defined by claim 3 wherein a plurality of phase encoding amplitudes are employed in step a).
Claim 6
Dependent Claim
17 words
The method as defined by claim 4 wherein alternate phase encoding amplitudes are employed in step d).
Claim 7
Dependent Claim
31 words
The method as defined by claim 5 wherein alternative phase encoding amplitudes are odd number frames employing odd number encoding amplitudes and even number frames employing even number phase encoding amplitudes.
Claim 8
Dependent Claim
29 words
The method as defined by claim 5 wherein each frame employs every Nth phase encoding amplitude where 1/N is the area of dynamic material in a field of view.
Claim 9
Dependent Claim
26 words
The method as defined by claim 2 wherein said magnetic resonance imaging is TRIADS and in which a motion cycle is mapped to phase encoding amplitude.
Claim 10
Dependent Claim
19 words
The method as defined by claim 2 wherein Fourier transform data are collected as spirals in Fourier transform space.
Claim 11
Dependent Claim
13 words
The method as defined by claim 2 wherein said imaging is cardiac imaging.
Claim 12
Dependent Claim
13 words
The method as defined by claim 2 wherein said imaging is functional MRI.
Claim 13
Dependent Claim
15 words
The method as defined by claim 2 wherein said imaging is based on respiration cycle.
Claim 14
Dependent Claim
19 words
The method as defined by claim 1 wherein said dynamic material is centrally located in said field of view.
Claim 15
Dependent Claim
34 words
The method as defined by claim 1 wherein said dynamic material is offset from a center of said field of view, and all measured data are multiplied by linearly varying phase shifts in k-space.
Claim 16
Dependent Claim
19 words
The method as defined by claim 1 wherein a plurality of phase encoding amplitudes are employed in step a).
Claim 17
Dependent Claim
17 words
The method as defined by claim 15 wherein alternate phase encoding amplitudes are employed in step d).
Claim 18
Dependent Claim
29 words
The method as defined by claim 15 wherein each frame employs every Nth phase encoding amplitude where 1/N is the area of dynamic material in a field of view.
Claim 19
Dependent Claim
131 words
Apparatus for dynamic magnetic resonance (MR) imaging of an object which occupies a full field of view and within which a dynamic portion exhibits time varying signal, said dynamic portion occupying substantially only a portion of the full field of view, said apparatus comprising: a) means obtaining MR data for a plurality of time frames, each time frame composed of subframes, b) means combining the data from multiple time frames to obtain data representative of an average image, c) means using said data representing an average image to obtain data representing the static portion of the object, and d) means using the data from the static portion obtained in step c) and the data from one subframe to produce an image of the dynamic portion of the object during said subframe.
Claim 20
Dependent Claim
131 words
Apparatus for dynamic magnetic resonance (MR) imaging of an object which occupies a full field of view and within which a dynamic portion exhibits time varying signal, said dynamic portion occupying substantially only a portion of the full field of view, said apparatus comprising: a) means obtaining MR data for a plurality of time frames, each time frame composed of subframes, b) means combining the data from multiple time frames to obtain data representative of an average image, c) means using said data representing an average image to obtain data representing the static portion of the object, and d) means using the data from the static portion obtained in step c) and the data from one subframe to produce an image of the dynamic portion of the object during said subframe.
Claim 21
Dependent Claim
165 words
Apparatus for magnetic resonance imaging known dynamic material in a field of view in an object having static material comprising: a) means establishing a magnetic field through said object, b) means applying a plurality of phase encoding amplitude pulses to said object for segmented k-space imaging and spin warp encoding, c) means obtaining magnetic resonance data for a plurality of frames of all material in said field of view, d) means averaging all magnetic resonance data to obtain an average image, e) means setting the dynamic material of said average image to zero to obtain an image of static material, f) means transforming said image of static material to generate a synthetic magnetic resonance data set of static data, g) means subtracting said synthetic magnetic resonance data set from said magnetic resonance data for each of said plurality of frames to produce magnetic resonance data sets for dynamic material in each frame, and h) means transforming said data sets for dynamic material to frame images.
Claim 22
Dependent Claim
165 words
Apparatus for magnetic resonance imaging known dynamic material in a field of view in an object having static material comprising: a) means establishing a magnetic field through said object, b) means applying a plurality of phase encoding amplitude pulses to said object for segmented k-space imaging and spin warp encoding, c) means obtaining magnetic resonance data for a plurality of frames of all material in said field of view, d) means averaging all magnetic resonance data to obtain an average image, e) means setting the dynamic material of said average image to zero to obtain an image of static material, f) means transforming said image of static material to generate a synthetic magnetic resonance data set of static data, g) means subtracting said synthetic magnetic resonance data set from said magnetic resonance data for each of said plurality of frames to produce magnetic resonance data sets for dynamic material in each frame, and h) means transforming said data sets for dynamic material to frame images.
Claim 23
Dependent Claim
45 words
Apparatus as defined by claim 19 wherein said f) means includes performing a reverse Fourier transform of said image to k-space, and said f) means includes Fourier transforming k-space data to image data, and said h) means includes Fourier transforming k-space data to image data.
Claim 24
Dependent Claim
20 words
Apparatus as defined by claim 20 wherein the magnetic resonance imaging is segmented k-space imaging using spin warp phase encoding.
Claim 25
Dependent Claim
19 words
Apparatus as defined by claim 20 wherein a plurality of phase encoding amplitudes are employed by said a) means.
Claim 26
Dependent Claim
17 words
Apparatus as defined by claim 22 wherein alternate phase encoding amplitudes are employed by said e) means.
Claim 27
Dependent Claim
30 words
Apparatus as defined by claim 23 wherein alternative phase encoding amplitudes are odd number frames employing odd number encoding amplitudes and even number frames employing even number phase encoding amplitudes.
Claim 28
Dependent Claim
28 words
Apparatus as defined by claim 23 wherein each frame employs every Nth phase encoding amplitude where 1/N is the area of dynamic material in a field of view.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-08-04 | 2001-02-03 | 2001-08-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-08-04 | 2005-02-03 | 2005-08-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-08-04 | 2009-02-03 | 2009-08-05 | $7700.00 | Window Closed / Lapsed |