US5645860A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Tissue graft and method for urinary urothelium reconstruction replacement
Assignee: Methodist Hospital
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Filing: 1996-04-16
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Granted: 1997-07-08
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Expires: 2016-04-16
Abstract
Abstract A method for surgical repair of a diseased or damaged bladder is described. Diseased or damaged bladder tissue is surgically replaced with submucosal tissue of a warm blooded vertebrate to promote regrowth of endogenous urinary bladder tissue.
Inventors
- 👤 Peter M. Knapp, Jr.
- 👤 James E. Lingeman
- 👤 Robert J. Demeter
- 👤 Stephen F. Badylak
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:10
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3604; A61L27/3629; A61K; A61K35/00; A61K35/12; A61K35/37; A61K35/38; A61L27/3641; A61L27/3679; A61L2430/00; A61L2430/22
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
77 words
A method of repairing a damaged or diseased portion of a urinary bladder by promoting the growth of endogenous urinary bladder tissues having a urine impermeable layer and a functional muscle layer which comprises a) surgically removing the damaged or diseased portion of the urinary bladder and b) replacing the removed portion of the bladder with a tissue graft construct comprising intestinal submucosa delaminated from both the tunica muscularis and the luminal portion of the tunica mucosa.
Claim 2
Independent Claim
77 words
A method of repairing a damaged or diseased portion of a urinary bladder by promoting the growth of endogenous urinary bladder tissues having a urine impermeable layer and a functional muscle layer which comprises a) surgically removing the damaged or diseased portion of the urinary bladder and b) replacing the removed portion of the bladder with a tissue graft construct comprising intestinal submucosa delaminated from both the tunica muscularis and the luminal portion of the tunica mucosa.
Claim 3
Dependent Claim
20 words
The method of claim 1, wherein the tissue graft construct is formed from two or more strips of intestinal tissue.
Claim 4
Independent Claim
76 words
A method of repairing a damaged or diseased portion of a urinary tract by promoting the growth of endogenous urothelial tissues having a urine impermeable layer and a functional muscle layer which comprises a) surgically removing the damaged or diseased portion of the urinary tract and b) replacing the removed portion of the tract with a tissue graft construct comprising intestinal submucosa delaminated from both the tunica muscularis and the luminal portion of the tunica mucosa.
Claim 5
Independent Claim
76 words
A method of repairing a damaged or diseased portion of a urinary tract by promoting the growth of endogenous urothelial tissues having a urine impermeable layer and a functional muscle layer which comprises a) surgically removing the damaged or diseased portion of the urinary tract and b) replacing the removed portion of the tract with a tissue graft construct comprising intestinal submucosa delaminated from both the tunica muscularis and the luminal portion of the tunica mucosa.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-07-07 | 2001-01-06 | 2001-07-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-07-07 | 2005-01-06 | 2005-07-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-07-07 | 2009-01-06 | 2009-07-08 | $7700.00 | Window Closed / Lapsed |