US5631278A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Methods of killing protozoal parasites
Assignee: Thomas Jefferson University
•
Filing: 1993-12-02
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Granted: 1997-05-20
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Expires: 2013-12-02
Abstract
Abstract Methods of inhibiting the proliferation of protozoal parasites employing taxol or taxol analogs are provided by the present invention. Such methods may be useful for treating such infections in mammals such as humans.
Inventors
- 👤 Theodore F. Taraschi
- 👤 Bruno Pouvelle
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 23:51
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/335; A61K31/337; Y; Y02; Y02A; Y02A50/00; Y02A50/30
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
48 words
A method of inhibiting the proliferation of a protozoal parasite comprising contacting the protozoal parasite with an amount of taxol or taxol analog effective to inhibit the proliferation of said parasite wherein said parasite is selected from the group consisting of Babesia, Pneumocystis, Cryptosporidium, Sarcocystis, Isospora, and Toxoplasma.
Claim 2
Independent Claim
48 words
A method of inhibiting the proliferation of a protozoal parasite comprising contacting the protozoal parasite with an amount of taxol or taxol analog effective to inhibit the proliferation of said parasite wherein said parasite is selected from the group consisting of Babesia, Pneumocystis, Cryptosporidium, Sarcocystis, Isospora, and Toxoplasma.
Claim 3
Dependent Claim
23 words
The method of claim 1 wherein the parasite is contacted with from about 0.1 μM to about 1 μM taxol or taxol analog.
Claim 4
Dependent Claim
18 words
The method of claim 1 wherein the period of contact is from about 8 to about 48 hours.
Claim 5
Dependent Claim
11 words
The method of claim 1 wherein said taxol analog is taxotere.
Claim 6
Independent Claim
33 words
A method of inhibiting the asexual reproduction of a Sporozoa protozoal parasite comprising contacting the protozoal parasite with an amount of taxol or taxol analog effective to inhibit the reproduction of said parasite.
Claim 7
Independent Claim
33 words
A method of inhibiting the asexual reproduction of a Sporozoa protozoal parasite comprising contacting the protozoal parasite with an amount of taxol or taxol analog effective to inhibit the reproduction of said parasite.
Claim 8
Dependent Claim
24 words
The method of claim 5, wherein said Sporozoa parasite is selected from the group consisting of Plasmodium, Babesia, Pneumocystis, Cryptosporidium, Sarcocystis, Isospora, and Toxoplasma.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-05-19 | 2000-11-18 | 2001-05-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-05-19 | 2004-11-18 | 2005-05-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-05-19 | 2008-11-18 | 2009-05-20 | $7700.00 | Window Closed / Lapsed |