Atrial and ventricular capture detection and threshold-seeking pacemaker

Claim 2

A dual chamber pacemaker pulse generator for attachment with atrial and ventricular pacing and sensing electrodes said electrodes being for delivering electrical pulses from said generator for pacing and sensing depolarizations of a patient's heart in the atrium and the ventricle respectively, said pacing being at adjustable atrial and ventricular pacing pulse energies wherein said generator comprises: variable escape interval timing means for establishing an atrial normal rate escape interval; atrial pace pulse generator means for generating an atrial pace pulse through said atrial pacing electrodes at the end of said atrial normal rate escape interval in the absence of an atrial sensed event signal at a normal pace pulse energy; atrial sensing means adapted to be coupled through said atrial sense electrodes for generating an atrial sensed event signal in response to a natural depolarization of atrial tissue during at least a major portion of said atrial normal rate escape interval; atrial-ventricular delay timing means for establishing an A-V delay interval commencing in timed relation to an atrial sensed event signal or an atrial pace pulse and where in relation to a pace pulse said A-V delay interval comprises a first and second temporal portion; ventricular sensing means adapted to be coupled to said ventricular electrodes for generating a ventricular sensed event signal in response to a depolarization of ventricular tissue; ventricular pace pulse generator means for generating a ventricular pace pulse at said ventricular electrodes at the end of said A-V delay interval in the absence of a ventricular sensed event signal detected within said A-V delay interval; atrial stimulation threshold test means for operating said escape interval timing means at atrial pace test escape intervals and for initiating the delivery of an atrial pace test stimulus by said atrial pace pulse generator means at the end of an atrial pace test escape interval operated by said atrial test means at an atrial pace test pulse energy varying from said normal atrial pace pulse energy in an atrial pace test cycle; atrial capture detection means responsive to said ventricular sensing means for declaring atrial capture following the delivery of an atrial pace test stimulus by the detection of a ventricular sensed event signal in said second temporal portion of the A-V delay interval following the delivery of the atrial pace test stimulus; and atrial loss of capture detection means responsive to said ventricular sensing means for declaring atrial loss of capture following the delivery of an atrial pace test stimulus by the absence of a ventricular sensed event signal detected in the A-V delay interval.

Claim 3

The pacemaker pulse generator of claim 1 wherein said atrial stimulation threshold test means further comprises: means for setting the atrial test escape interval to correspond to an atrial pace test rate exceeding the natural atrial depolarization rate of the patient's atrium; and means for determining a starting atrial pace test pulse energy that consistently results in capture of the patient's atrium at said atrial test rate.

Claim 4

The pacemaker pulse generator of claim 2 wherein said atrial capture detection means further comprises: means for defining a time window interval commencing with said A-V delay interval and timing out at a time within said A-V delay interval before a conducted ventricular depolarization resulting from the capture of the atrium would have been expected to appear at the site of the ventricular electrodes said time window thereby defining a portion of said A-V delay interval; and means for declaring a ventricular sensed event occurring during said time window interval as a natural ventricular depolarization not resulting from capture of the patient's atrium by the preceding atrial pace test stimlus and not indicative of atrial capture or loss of capture by the preceding atrial pace test stimulus.

Claim 5

The pacemaker pulse generator of claim 3 wherein said atrial stimulation threshold test means further comprises: means for reducing the atrial pace test pulse energy of the succeeding atrial pace test stimuli and repeating the delivery of atrial pace test stimuli by said atrial pace pulse generator means at the end of successive test escape intervals at successively reduced atrial test pace pulse energies until atrial loss of capture is declared at a reduced atrial test pulse energy; and means responsive to declaration of atrial loss of capture for repeating the delivery of atrial pace test stimuli by said atrial pace pulse generator means at the end of successive atrial test escape intervals at the atrial pace test pulse energy of a preceding declared atrial capture until such atrial capture is declared at least twice.

Claim 6

The pacemaker pulse generator of claim 4 wherein said pulse energy reducing means further comprises means for reducing the atrial pace test stimulus pulse width until atrial loss of capture is declared at a reduced pulse width indicative of the atrial stimulation pulse width threshold and for thereafter reducing the atrial pace test stimulus pulse amplitude until atrial loss of capture is declared at a reduced pulse amplitude indicative of the atrial stimulation pulse amplitude threshold.

Claim 7

The pacemaker pulse generator of claim 5 further comprising: means for storing a value representative of the atrial test stimulus pulse width and pulse amplitude at atrial loss of capture or at atrial capture; and means operable on command of a remote programmer located outside the patient's body for telemetering said stored atrial pulse width and amplitude values to said remote programmer.

Claim 8

The pacemaker pulse generator of claim 6 further comprising: means for setting the normal atrial pace pulse energy at a normal pace pulse width and pulse amplitude exceeding the atrial loss of capture stimulation threshold pulse width and pulse amplitude by a safety margin.

Claim 9

The pacemaker pulse generator of claim 7 wherein said atrial pace pulse generator means further comprises: means responsive to the atrial loss of capture declared by said atrial loss of capture detection means for generating an atrial backup pace pulse for pacing the atrium at the end of the following atrial pace normal rate escape interval.

Claim 10

The pacemaker pulse generator of claim 1 wherein said atrial pace pulse generator means further comprises: means responsive to the atrial loss of capture declared by said atrial loss of capture detection means for generating an atrial backup pace pulse for pacing the atrium at the end of the following atrial pace normal rate escape interval.

Claim 11

The pacemaker pulse generator of claim 1 further comprising: means for storing a value representing the energy of an atrial test pulse that caused said atrial loss of capture detection means to determine loss of capture due to absence of a sensed ventricular event as atrial stimulation threshold data.

Claim 12

The pacemaker pulse generator of claim 10 further comprising: means for setting the normal atrial pace pulse energy at a normal pace pulse energy exceeding an energy value represented by the atrial stimulation threshold data by a safety margin.

Claim 13

The pacemaker pulse generator of claim 1 wherein said atrial capture detection means further comprises: means for defining a time window interval commencing with said A-V delay interval and timing out at a time within said A-V delay interval before the conducted ventricular depolarization resulting from the capture of the atrium would be expected to appear at the site of the ventricular electrodes; and means for declaring a ventricular sensed event occurring during said time window interval as a natural ventricular depolarization not resulting from capture of the patient's atrium by the preceding atrial pace test stimulus and not indicative of atrial capture or loss of capture by the preceding atrial test stimulus.

Claim 14

The pacemaker pulse generator of claim 12 wherein said atrial stimulation threshold test means further comprises: means for reducing the atrial test pulse energy of the succeeding atrial pace test stimuli and repeating the delivery of atrial pace test stimuli by said atrial pace pulse generator means at the end of successive test escape intervals at successively reduced atrial test pace pulse energies until atrial loss of capture is declared at a reduced atrial test pulse energy; and means responsive to declaration of atrial loss of capture for repeating the delivery of atrial pace test stimuli by said atrial pace pulse generator means at the end of successive atrial test escape intervals at the atrial pace test pulse energy of a preceding declared atrial capture until such atrial capture is declared at least twice.

Claim 15

A dual chamber pacemaker pulse generator for attachment with atrial and ventricular pacing and sensing electrodes said electrodes being for delivering electrical pulses from said generator for pacing and sensing depolarizations of a patient's heart in the atrium and the ventricle, respectively, aid pacing being at adjustable atrial and ventricular pacing pulse energies and wherein said generator comprises: variable escape interval timing means for establishing an atrial normal rate escape interval and an atrial test escape interval; atrial pace pulse generator means for generating an atrial pace pulse through said atrial pacing electrodes at the end of said atrial normal rate escape interval in the absence of an atrial sensed event signal at a normal pace pulse energy; atrial sensing means adapted to be coupled through said atrial sense electrodes for generating an atrial sensed event signal in response to a natural depolarization of atrial tissue during at least a major portion of said atrial normal rate escape interval; atrial-ventricular delay timing means for establishing an A-V delay interval commencing in timed relation to an atrial sensed event signal or an atrial pace pulse; ventricular sensing means adapted to be coupled through said ventricular sense electrodes for generating a ventricular sensed event signal ventricular pace pulse generator means for generating a ventricular pace pulse through said ventricular pacing electrodes at the end of said A-V delay interval in the absence of a ventricular sensed event signal detected within said A-V delay interval; means for establishing a ventricular refractory period time interval following delivery of a ventricular pace pulse; ventricular stimulation threshold test means periodically operable for initiating a ventricular stimulation threshold test further comprising: means for operating said escape interval timing means at atrial pace test escape intervals and said atrial-ventricular delay timing means at a test A-V delay interval commencing in timed relation to the delivery of an atrial pace pulse; means for operating said atrial pace pulse generator means to generate an atrial pace pulse at the end of the atrial pace test escape interval at an atrial pace pulse energy sufficient to ensure that atrial capture is achieved and that a conducted ventricular depolarization follows outside said test A-V delay interval; and means for initiating the delivery of a ventricular pace test stimulus by said ventricular pace pulse generator means at the end of said test A-V delay interval which is timed to render the patient's ventricle refractory to potential subsequent intrinsically conducted depolarization stimulus captures and depolarizes the ventricle; and ventricular capture detection means responsive to said ventricular sensing means for declaring ventricular capture by the absence of a ventricular sensed event signal in the ventricular refractory period following delivery of the ventricular pace test stimulus.

Claim 16

A dual chamber pacemaker pulse generator for attachment with atrial and ventricular pacing and sensing electrodes said electrodes being for delivering electrical pulses from said generator for pacing and sensing depolarizations of a patient's heart in the atrium and the ventricle, respectively, aid pacing being at adjustable atrial and ventricular pacing pulse energies and wherein said generator comprises: variable escape interval timing means for establishing an atrial normal rate escape interval and an atrial test escape interval; atrial pace pulse generator means for generating an atrial pace pulse through said atrial pacing electrodes at the end of said atrial normal rate escape interval in the absence of an atrial sensed event signal at a normal pace pulse energy; atrial sensing means adapted to be coupled through said atrial sense electrodes for generating an atrial sensed event signal in response to a natural depolarization of atrial tissue during at least a major portion of said atrial normal rate escape interval; atrial-ventricular delay timing means for establishing an A-V delay interval commencing in timed relation to an atrial sensed event signal or an atrial pace pulse; ventricular sensing means adapted to be coupled through said ventricular sense electrodes for generating a ventricular sensed event signal ventricular pace pulse generator means for generating a ventricular pace pulse through said ventricular pacing electrodes at the end of said A-V delay interval in the absence of a ventricular sensed event signal detected within said A-V delay interval; means for establishing a ventricular refractory period time interval following delivery of a ventricular pace pulse; ventricular stimulation threshold test means periodically operable for initiating a ventricular stimulation threshold test further comprising: means for operating said escape interval timing means at atrial pace test escape intervals and said atrial-ventricular delay timing means at a test A-V delay interval commencing in timed relation to the delivery of an atrial pace pulse; means for operating said atrial pace pulse generator means to generate an atrial pace pulse at the end of the atrial pace test escape interval at an atrial pace pulse energy sufficient to ensure that atrial capture is achieved and that a conducted ventricular depolarization follows outside said test A-V delay interval; and means for initiating the delivery of a ventricular pace test stimulus by said ventricular pace pulse generator means at the end of said test A-V delay interval which is timed to render the patient's ventricle refractory to potential subsequent intrinsically conducted depolarization stimulus captures and depolarizes the ventricle; and ventricular capture detection means responsive to said ventricular sensing means for declaring ventricular capture by the absence of a ventricular sensed event signal in the ventricular refractory period following delivery of the ventricular pace test stimulus.

Claim 17

The pacemaker pulse generator of claim 14 wherein said ventricular stimulation threshold test means further comprises: means for setting the atrial test escape interval to correspond to an atrial test rate exceeding the natural atrial depolarization rate of the patient's atrium; and means for determining a starting atrial pace and ventricular pace test pulse energy that consistently results in capture of the patient's atrium and ventricle, respectively, at said atrial test rate.

Claim 18

The pacemaker pulse generator of claim 14 further comprising: ventricular loss of capture detection means responsive to said ventricular sensing means for declaring ventricular loss of capture following the delivery of a ventricular pace test stimulus by the presence of a ventricular sensed event signal detected within the ventricular refractory period.

Claim 19

The pacemaker pulse generator of claim 16 wherein said ventricular loss of capture detection means further comprises: means operable in response to a declaration of ventricular loss of capture for repeating the delivery of ventricular pace test stimuli by said ventricular pace pulse generator means during a next test pacing cycle at the ventricular test pace pulse energy previously declared as ventricular capture to confirm the threshold capture energy over at least two test pacing cycles.

Claim 20

The pacemaker pulse generator of claim 17 further comprising a test pacing cycle repeating means for reducing the ventricular pace test stimulus pulse width through a series of test pacing cycles until ventricular loss of capture is declared at a reduced pulse width indicative of the ventricular stimulation pulse width threshold and for thereafter reducing the ventricular pace test stimulus pulse amplitude through a series of test pacing cycles until ventricular loss of capture is declared at a reduced pulse amplitude indicative of the ventricular stimulation pulse amplitude threshold.

Claim 21

The pacemaker pulse generator of claim 18 further comprising: means for storing values representing the ventricular test pulse width and pulse amplitude at ventricular loss of capture and/or ventricular capture as ventricular threshold test data; and means operable on command of a remote programmer located outside the patient's body for telemetering said stored ventricular threshold test data to said remote programmer.

Claim 22

The pacemaker pulse generator of claim 19 further comprising: means for setting a normal ventricular pace pulse energy value at a normal pace pulse width and pulse amplitude exceeding at least one of the ventricular loss of capture stimulation threshold pulse width and pulse amplitude values by a safety margin.

Claim 23

The pacemaker pulse generator of claim 20 wherein said ventricular loss of capture detection means further comprises: means responsive to the ventricular loss of capture declared by said ventricular loss of capture detection means for providing a backup pacing pulse to capture the ventricle at the end of the following normal escape interval.

Claim 24

The pacemaker pulse generator of claim 16 wherein said ventricular loss of capture detection means further comprises: means responsive to the ventricular loss of capture declared by said ventricular loss of capture detection means for providing a backup pacing pulse to capture the ventricle at the end of the following normal escape interval.

Claim 25

The pacemaker pulse generator of claim 16 further comprising: means for storing the ventricular test pulse width and pulse amplitude values at ventricular loss of capture and/or ventricular capture as ventricular threshold test data; and means operable on command of a remote programmer located outside the patient's body for telemetering said stored ventricular threshold test data to said remote programmer.

Claim 26

The pacemaker pulse generator of claim 16 further comprising: means for setting a normal ventricular pace pulse energy at a normal pace pulse energy exceeding the ventricular loss of capture stimulation threshold pulse energy by a safety margin.

Claim 27

The pacemaker pulse generator of claim 14 further comprising a test pacing cycle repeating means for reducing the ventricular pace test stimulus pulse energy through a series of test pacing cycles until ventricular loss of capture is declared at a reduced pulse energy level indicative of the ventricular stimulation pulse energy threshold.

Claim 28

A dual chamber pacemaker implantable pulse generator for attachment with atrial and ventricular pacing and sensing electrodes said electrodes being for delivering electrical pulses from said generator for pacing and sensing depolarization of a patient's heart in the atrium and the ventricle respectively, said being at adjustable atrial and ventricular pacing pulse energies, said generator comprising: variable escape interval timing means for establishing a normal atrial rate escape interval; atrial pace pulse generator means for generating an atrial pace pulse through said atrial pacing electrodes at the end of said normal atrial rate escape interval in the absence of an atrial sensed event signal at a normal pace pulse energy; atrial sensing means adapted to be coupled through said atrial sense electrodes for generating an atrial sensed event signal in response to a natural depolarization of atrial tissue during at least a major portion of said normal atrial rate escape interval; atrial-ventricular delay timing means for establishing an A-V delay interval commencing in timed relation to an atrial sensed event signal or an atrial pace pulse and where in relation to a pace pulse said A-V delay interval comprises a first and second temporal portion; ventricular sensing means adapted to be coupled to said ventricular electrodes for generating a ventricular sensed event signal in response to a depolarization of ventricular tissue; ventricular pace pulse generator means for generating a ventricular pace pulse at said ventricular electrodes at the end of said A-V delay interval in the absence of a ventricular sensed event signal detected within said A-V delay interval; means for establishing a ventricular refractory period time interval following delivery of a ventricular pace pulse; pace test stimulus by the presence of a ventricular sensed event signal detected within the ventricular refractory period; and ventricular capture detection means responsive to said ventricular sensing means for declaring ventricular capture by the absence of a ventricular sensed event signal in the ventricular refractory period following delivery of the ventricular pace test stimulus; and means for periodically triggering the operation of said atrial and ventricular stimulation threshold test means in a predetermined sequence of successive test pacing cycles to derive atrial and ventricular stimulation threshold test data related to the declarations of atrial and ventricular capture and loss of capture.

Claim 29

A dual chamber pacemaker implantable pulse generator for attachment with atrial and ventricular pacing and sensing electrodes said electrodes being for delivering electrical pulses from said generator for pacing and sensing depolarization of a patient's heart in the atrium and the ventricle respectively, said being at adjustable atrial and ventricular pacing pulse energies, said generator comprising: variable escape interval timing means for establishing a normal atrial rate escape interval; atrial pace pulse generator means for generating an atrial pace pulse through said atrial pacing electrodes at the end of said normal atrial rate escape interval in the absence of an atrial sensed event signal at a normal pace pulse energy; atrial sensing means adapted to be coupled through said atrial sense electrodes for generating an atrial sensed event signal in response to a natural depolarization of atrial tissue during at least a major portion of said normal atrial rate escape interval; atrial-ventricular delay timing means for establishing an A-V delay interval commencing in timed relation to an atrial sensed event signal or an atrial pace pulse and where in relation to a pace pulse said A-V delay interval comprises a first and second temporal portion; ventricular sensing means adapted to be coupled to said ventricular electrodes for generating a ventricular sensed event signal in response to a depolarization of ventricular tissue; ventricular pace pulse generator means for generating a ventricular pace pulse at said ventricular electrodes at the end of said A-V delay interval in the absence of a ventricular sensed event signal detected within said A-V delay interval; means for establishing a ventricular refractory period time interval following delivery of a ventricular pace pulse; pace test stimulus by the presence of a ventricular sensed event signal detected within the ventricular refractory period; and ventricular capture detection means responsive to said ventricular sensing means for declaring ventricular capture by the absence of a ventricular sensed event signal in the ventricular refractory period following delivery of the ventricular pace test stimulus; and means for periodically triggering the operation of said atrial and ventricular stimulation threshold test means in a predetermined sequence of successive test pacing cycles to derive atrial and ventricular stimulation threshold test data related to the declarations of atrial and ventricular capture and loss of capture.

Claim 30

The pacemaker pulse generator of claim 26 further comprising: means for storing said atrial and ventricular stimulation threshold test data; means for retriving and transmitting said stored atrial and ventricular stimulation threshold test data on command to a remote receiver for review and analysis.

Claim 31

The pacemaker pulse generator of claim 26 further comprising: means for storing said atrial and ventricular stimulation threshold test data; and means for adjusting the atrial and ventricular pace pulse energies of the atrial and ventricular pace pulses generated by said atrial and ventricular pace pulse generator means to energy values in excess of said stored atrial and ventricular stimulation threshold test data.

Claim 32

The pacemaker pulse generator of claim 26 wherein said atrial capture detection means further comprises: means for defining a time window interval commencing with said A-V delay interval and timing out at a time within said A-V delay interval before the conducted ventricular depolarization resulting from the capture of the atrium would be expected to appear at the site of the ventricular electrodes; and means for declaring a ventricular sensed event occurring during said time window interval as a natural ventricular depolarization not resulting from capture of the patient's atrium by the preceding atrial pace test stimulus and not indicative of atrial capture or loss of capture by the preceding atrial pace test stimulus.

Claim 33

The pacemaker pulse generator of claim 26 wherein said ventricular loss of capture detection means further comprises: means responsive to the ventricular loss of capture declared by said ventricular loss of capture detection means for providing a backup pacing cycle employing backup atrial and ventricular pace pulse energies at the end of the following normal escape interval.

Claim 34

The pacemaker pulse generator of claim 26 wherein said test pacing cycle repeating means further comprises: means for reducing the ventricular pace test stimulus pulse width through a series of test pacing cycles until ventricular loss of capture is declared at a reduced pulse width indicative of the ventricular stimulation pulse width threshold and for thereafter reducing the ventricular pace test stimulus pulse amplitude through a series of test pacing cycles until ventricular loss of capture is declared at a reduced pulse amplitude indicative of the ventricular stimulation pulse amplitude threshold.

Claim 35

The pacemaker pulse generator of claim 26 wherein said test pacing cycle repeating means further comprises: means for reducing the atrial test pulse energy of the succeeding atrial pace test pulse and repeating delivery of atrial pace test pulse by said atrial pace pulse generator means at the end of successive test escape intervals at successively reduced atrial test pace pulse energies until atrial loss of capture is declared at a reduced atrial test pulse energy; and means responsive to declaration of atrial loss of capture for repeating the delivery of atrial pace test stimuli by said atrial pace pulse generator means at the end of successive atrial test escape intervals at the atrial pace test pulse energy of a preceding declared atrial capture until such atrial capture is declared at least twice.

Claim 36

The pacemaker pulse generator of claim 32 wherein said test pacing cycle repeating means further comprises: means for reducing a ventricular pace test pulse width through a series of test pacing cycles until ventricular loss of capture is declared at a reduced pulse width indicative of the ventricular stimulation pulse width threshold and for thereafter reducing the ventricular pace test stimulus pulse amplitude through a series of test pacing cycles until ventricular loss of capture is declared at a reduced pulse amplitude indicative of the ventricular stimulation pulse amplitude threshold.

Claim 37

In a pacemaker pulse generator having atrial and ventricular pulse generators for generating and applying atrial and ventricular pacing pulses to the atrium and ventricle of the heart separated by an A-V delay interval to evoke stimulated atrial and ventricular depolarizations and capture the atrium and ventricle and a ventricular sense amplifier for sensing natural depolarizations of the ventricle, a method of testing for the stimulation threshold energy of the ventricle comprising the steps of: determining the patient's atrial escape interval; operating said atrial pulse generator to deliver an atrial pace pulse at an energy sufficient to capture the atrium when said atrial escape interval times out; setting a test pace A-V delay interval; operating said ventricular pulse generator to deliver a ventricular test stimulus at the end of said test pace A-V delay interval; setting a ventricular sense time window; operating said ventricular sense amplifier during said ventricular sense time window to sense a depolarization of the ventricle; declaring capture of the ventricle by the ventricular test stimulus if a depolarization of the ventricle is not sensed in the ventricular sense time window; and declaring loss of capture of the ventricle by the ventricular test stimulus if a depolarization of the ventricle is sensed in the ventricular sense time window.

Claim 38

In a pacemaker pulse generator having atrial and ventricular pulse generators for generating and applying atrial and ventricular pacing pulses to the atrium and ventricle of the heart separated by an A-V delay interval to evoke stimulated atrial and ventricular depolarizations and capture the atrium and ventricle and a ventricular sense amplifier for sensing natural depolarizations of the ventricle, a method of testing for the stimulation threshold energy of the ventricle comprising the steps of: determining the patient's atrial escape interval; operating said atrial pulse generator to deliver an atrial pace pulse at an energy sufficient to capture the atrium when said atrial escape interval times out; setting a test pace A-V delay interval; operating said ventricular pulse generator to deliver a ventricular test stimulus at the end of said test pace A-V delay interval; setting a ventricular sense time window; operating said ventricular sense amplifier during said ventricular sense time window to sense a depolarization of the ventricle; declaring capture of the ventricle by the ventricular test stimulus if a depolarization of the ventricle is not sensed in the ventricular sense time window; and declaring loss of capture of the ventricle by the ventricular test stimulus if a depolarization of the ventricle is sensed in the ventricular sense time window.

Claim 39

In a pacemaker pulse generator having an atrial pulse generator for generating and applying atrial pacing pulses to the atrium of the heart to evoke a stimulated depolarization and capture the atrium and a ventricular sense amplifier for sensing natural depolarizations of the ventricle, apparatus for testing for the stimulation threshold energy of the atrium comprising: means for determining the patient's atrial escape interval; means for operating said atrial pulse generator to deliver an atrial test pulse at a test energy to the atrium in the atrial escape interval timed to capture the atrium if the test energy is sufficient to capture the atrium after said atrial escape interval times out; means for setting a paced A-V delay interval beginning after a PVC blanking period following said atrial test pulse; means for operating the ventricular sense amplifier during at least the paced A-V delay interval to sense a depolarization of the ventricle; means for declaring capture of the atrium by the atrial test pacing pulse if a depolarization of the ventricle is sensed in the paced A-V delay interval; and means for declaring loss of capture of the atrium by the atrial test pacing pulse if a depolarization of the ventricle is not sensed in the paced A-V delay interval.

Claim 40

In a pacemaker pulse generator having an atrial pulse generator for generating and applying atrial pacing pulses to the atrium of the heart to evoke a stimulated depolarization and capture the atrium and a ventricular sense amplifier for sensing natural depolarizations of the ventricle, apparatus for testing for the stimulation threshold energy of the atrium comprising: means for determining the patient's atrial escape interval; means for operating said atrial pulse generator to deliver an atrial test pulse at a test energy to the atrium in the atrial escape interval timed to capture the atrium if the test energy is sufficient to capture the atrium after said atrial escape interval times out; means for setting a paced A-V delay interval beginning after a PVC blanking period following said atrial test pulse; means for operating the ventricular sense amplifier during at least the paced A-V delay interval to sense a depolarization of the ventricle; means for declaring capture of the atrium by the atrial test pacing pulse if a depolarization of the ventricle is sensed in the paced A-V delay interval; and means for declaring loss of capture of the atrium by the atrial test pacing pulse if a depolarization of the ventricle is not sensed in the paced A-V delay interval.

Claim 41

In a pacemaker pulse generator having atrial and ventricular pulse generators for generating and applying atrial and ventricular pacing pulses to the atrium and ventricle of the heart separated by an A-V delay interval to evoke stimulated atrial and ventricular depolarizations and capture the atrium and ventricle and a ventricular sense amplifier for sensing natural depolarizations of the ventricle, apparatus for testing for the stimulation threshold energy of the ventricle comprising: means for determining the patient's atrial escape interval; means for operating said atrial pulse generator to deliver an atrial pace pulse at an energy sufficient to capture the atrium after said atrial escape interval times out; means for setting a test pace A-V delay interval; means for operating said ventricular pulse generator to deliver a ventricular test stimulus at the end of said test pace A-V delay interval; means for setting a ventricular sense time window; means for operating said ventricular sense amplifier during said ventricular sense time window to sense a depolarization of the ventricle; means for declaring capture of the ventricle by the ventricular test stimulus if a depolarization of the ventricle is not sensed in the ventricular sense time window; and means for declaring loss of capture of the ventricle by the ventricular test stimulus if a depolarization of the ventricle is sensed in the ventricular sense time window.

Claim 42

In a pacemaker pulse generator having atrial and ventricular pulse generators for generating and applying atrial and ventricular pacing pulses to the atrium and ventricle of the heart separated by an A-V delay interval to evoke stimulated atrial and ventricular depolarizations and capture the atrium and ventricle and a ventricular sense amplifier for sensing natural depolarizations of the ventricle, apparatus for testing for the stimulation threshold energy of the ventricle comprising: means for determining the patient's atrial escape interval; means for operating said atrial pulse generator to deliver an atrial pace pulse at an energy sufficient to capture the atrium after said atrial escape interval times out; means for setting a test pace A-V delay interval; means for operating said ventricular pulse generator to deliver a ventricular test stimulus at the end of said test pace A-V delay interval; means for setting a ventricular sense time window; means for operating said ventricular sense amplifier during said ventricular sense time window to sense a depolarization of the ventricle; means for declaring capture of the ventricle by the ventricular test stimulus if a depolarization of the ventricle is not sensed in the ventricular sense time window; and means for declaring loss of capture of the ventricle by the ventricular test stimulus if a depolarization of the ventricle is sensed in the ventricular sense time window.