US5582596A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Applicator for applying a biocompatible adhesive
Assignee: Chemo Sero Therapeutic Research Institute Kaketsuken
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Filing: 1993-09-24
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Granted: 1996-12-10
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Expires: 2013-09-24
Abstract
Abstract An applicator for applying a biocompatible adhesive containing human or aal protein as a principal ingredient to a surgical site of living body includes a housing to which a sterile gas is supplied, a sterile-gas supply tube connected to the housing, two adjacent sterile-gas ejecting nozzles for ejecting the sterile gas in the same direction, two adapters to which respective nozzles of syringe barrels are connected, and a pair of solution tubes, each having one end connected to the adapter and the other end protruded outwardly from the sterile gas ejection nozzle through an interior of the housing. Respective solutions supplied from the syringes via the pair of barrel adapters are ejected from the outlets of the solution tubes. The sterile gas is ejected from two sterile-gas ejection nozzles in the same direction. Consequently, the solutions are sprayed and mixed by the sterile gas, and then applied to the surgical site.
Inventors
- 👤 Nobuto Fukunaga
- 👤 Katsumi Kawakami
- 👤 Takanori Uchida
- 👤 Yoshimitsu Ishihara
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 22:38
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/00491; A61L; A61L26/00; A61L26/0061; A61B2017/00495
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
242 words
An applicator useful for applying a biocompatible adhesive containing human or animal protein to a surgical site of a living body, comprising a spray head, a pair of syringes each including a barrel and a nozzle at one end of the barrel, the syringes adapted to feed a protein solution and a coagulation solution, wherein the nozzles are fitted into the spray head, wherein the spray head is adapted to spray the protein and coagulation solutions fed from the syringes by ejection of a sterile gas, wherein the spray head comprises a housing including a pair of adapters for receiving the nozzles of the syringes, a pair of adjacent sterile-gas ejecting nozzles in the housing, each having a longitudinal axes, wherein the longitudinal axis thereof are arranged for guiding and ejecting the sterile gas, and a pair of solution tubes, one arranged and associated within each sterile-gas ejecting nozzle, each having a longitudinal axes parallel to the longitudinal axes of the gas ejecting nozzles, wherein one end of each of the solution tubes is connected to one of the adapters, and the other end of each solution tube protrudes from the end of the associated sterile-gas ejecting nozzle, wherein the solution tubes are arranged such that when the solutions are fed from the syringes, they are conveyed through the solution tubes and ejected therefrom, and a sterile-gas supply tube connected to the interior of the housing adapted to supply the sterile gas.
Claim 2
Dependent Claim
242 words
An applicator useful for applying a biocompatible adhesive containing human or animal protein to a surgical site of a living body, comprising a spray head, a pair of syringes each including a barrel and a nozzle at one end of the barrel, the syringes adapted to feed a protein solution and a coagulation solution, wherein the nozzles are fitted into the spray head, wherein the spray head is adapted to spray the protein and coagulation solutions fed from the syringes by ejection of a sterile gas, wherein the spray head comprises a housing including a pair of adapters for receiving the nozzles of the syringes, a pair of adjacent sterile-gas ejecting nozzles in the housing, each having a longitudinal axes, wherein the longitudinal axis thereof are arranged for guiding and ejecting the sterile gas, and a pair of solution tubes, one arranged and associated within each sterile-gas ejecting nozzle, each having a longitudinal axes parallel to the longitudinal axes of the gas ejecting nozzles, wherein one end of each of the solution tubes is connected to one of the adapters, and the other end of each solution tube protrudes from the end of the associated sterile-gas ejecting nozzle, wherein the solution tubes are arranged such that when the solutions are fed from the syringes, they are conveyed through the solution tubes and ejected therefrom, and a sterile-gas supply tube connected to the interior of the housing adapted to supply the sterile gas.
Claim 3
Dependent Claim
34 words
An applicator according to claim 1, wherein each of the sterile-gas ejecting nozzles has its inner periphery surface formed with a plurality of ribs for supporting the associated solution tube in coaxial relationship therewith.
Claim 4
Dependent Claim
21 words
An applicator according to claim 1, wherein the distance between the pair of solution tubes is about 1 to 20 mm.
Claim 5
Dependent Claim
21 words
An applicator according to claim 1, wherein the distance between the pair of solution tubes is about 1 to 5 mm.
Claim 6
Dependent Claim
24 words
An applicator according to claim 1, wherein each solution tubes independently protrude outwardly from the associated sterile-gas ejection nozzles about 0.1 to 10 mm.
Claim 7
Dependent Claim
39 words
An applicator according to claim 1, wherein the spray head has an elongated hollow extension of about 5 to 50 cm, wherein the elongated hollow extension includes a pair of through holes through which the solution tubes outwardly protrude.
Claim 8
Dependent Claim
27 words
An applicator according to claim 6, wherein the sterile-gas supply tube is connected to the interior of the elongated hollow extension of about 5 to 50 cm.
Claim 9
Dependent Claim
16 words
An applicator according to claim 1, which further comprises a holder holding the pair of syringes.
Claim 10
Dependent Claim
23 words
An applicator according to claim 8, wherein the holder includes a pair of parallel concave portions adapted to receive the pair of syringes.
Claim 11
Dependent Claim
20 words
An applicator according to claim 1, which further comprises a pair of plungers inserted into the pair of syringe barrels.
Claim 12
Dependent Claim
20 words
An applicator according to claim 10, which further comprises an actuator holder holding and simultaneously moving the pair of plungers.
Claim 13
Dependent Claim
91 words
An applicator according to claim 1, which further comprises a pair of plungers adapted to be inserted into the pair of syringe barrels, a holder holding the pair of syringes, an actuator holding the pair of plungers, and a frame including a supporting member supporting the holder; a pushing member for biasing and moving the actuator; a sterile gas supply source for supplying the sterile gas; and switching means for controlling a supply of the sterile gas from the sterile gas supply source and for controlling movement of the pushing member.
Claim 14
Dependent Claim
24 words
An applicator according to claim 12, wherein the sterile gas supply source is a portable gas cylinder adapted to include the sterile gas therein.
Claim 15
Dependent Claim
11 words
An applicator according to claim 12, which is a gun-type applicator.
Claim 16
Dependent Claim
28 words
An applicator according to claim 1, wherein the sterile-gas supply tube includes a sterilizing filter adapted to sterilize the gas before the gas is introduced into the housing.
Claim 17
Dependent Claim
175 words
A spray head useful in an applicator for applying a biocompatible adhesive containing human or animal protein to a surgical site of a living body, comprising a housing including a pair of adapters for receiving nozzles of a syringe, a pair of adjacent sterile-gas ejecting nozzles in the housing, each having a longitudinal axes, wherein the longitudinal axis thereof are arranged for guiding and ejecting a sterile gas, and a pair of solution tubes, one arranged and associated within each sterile-gas ejecting nozzle, each having a longitudinal axes parallel to the longitudinal axes of the gas ejecting nozzles, wherein one end of each of the solution tubes is connected to one of the adapters, and the other end of each solution tube protrudes from the end of the associated sterile-gas ejecting nozzle, wherein the solution tubes are arranged such that when the solutions are fed from syringes, they are conveyed through the solution tubes and ejected therefrom, and a sterile-gas supply tube connected to the interior of the housing adapted to supply the sterile gas.
Claim 18
Dependent Claim
175 words
A spray head useful in an applicator for applying a biocompatible adhesive containing human or animal protein to a surgical site of a living body, comprising a housing including a pair of adapters for receiving nozzles of a syringe, a pair of adjacent sterile-gas ejecting nozzles in the housing, each having a longitudinal axes, wherein the longitudinal axis thereof are arranged for guiding and ejecting a sterile gas, and a pair of solution tubes, one arranged and associated within each sterile-gas ejecting nozzle, each having a longitudinal axes parallel to the longitudinal axes of the gas ejecting nozzles, wherein one end of each of the solution tubes is connected to one of the adapters, and the other end of each solution tube protrudes from the end of the associated sterile-gas ejecting nozzle, wherein the solution tubes are arranged such that when the solutions are fed from syringes, they are conveyed through the solution tubes and ejected therefrom, and a sterile-gas supply tube connected to the interior of the housing adapted to supply the sterile gas.
Claim 19
Dependent Claim
35 words
A spray head according to claim 16, wherein each of the sterile-gas ejecting nozzles has its inner periphery surface formed with a plurality of ribs for supporting the associated solution tube in coaxial relationship therewith.
Claim 20
Dependent Claim
22 words
A spray head according to claim 16, wherein the distance between the pair of solution tubes is about 1 to 20 mm.
Claim 21
Dependent Claim
22 words
A spray head according to claim 16, wherein the distance between the pair of solution tubes is about 1 to 5 mm.
Claim 22
Dependent Claim
25 words
A spray head according to claim 16, wherein each solution tubes independently protrude outwardly from the associated sterile-gas ejection nozzles about 0.1 to 10 mm.
Claim 23
Dependent Claim
40 words
A spray head according to claim 16, wherein the spray head has an elongated hollow extension of about 5 to 50 cm, wherein the elongated hollow extension includes a pair of through holes through which the solution tubes outwardly protrude.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-12-10 | 2000-06-10 | 2000-12-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-12-10 | 2004-06-10 | 2004-12-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-12-10 | 2008-06-10 | 2008-12-10 | $7700.00 | Window Closed / Lapsed |