US5569198A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Microporous catheter
Assignee: Mmc/gatx Partnership No1
•
Filing: 1995-01-23
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Granted: 1996-10-29
•
Expires: 2015-01-23
Abstract
Abstract An apparatus for delivering an agent to a treatment area. The apparatus includes a catheter that has a distal portion and a proximal portion. The catheter defines a lumen. A pressure regulator is in fluid communication with the lumen. A selectively inflatable member is also in fluid communication with the lumen, and is formed from a membrane. The membrane has first and second portions. The first portion defines pores sized from about 0.05μ to about 1μ and has a pore density from about 10 6 pores/cm 2 to about 10 9 pores/cm 2 . The flux rate is from about 0.001 ml/(min·cm 2 ·atm) to about 0.4 ml/(min·cm 2 ·atm). The second portion is substantially impermeable.
Inventors
- 👤 Joel R. Racchini
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 03:50
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61N; A61N1/00; A61N1/18; A61N1/20; A61N1/30; A61N1/303; A61N1/306; A61M25/0043; A61M2025/0057; A61M2025/1043; A61M2025/105
Claims Analysis
Total Claims: 30
Claim 1
Independent Claim
94 words
An apparatus for delivering an agent to a treatment area using pressure, the apparatus not including phoretic delivery means, the apparatus comprising: a catheter having a distal portion and a proximal portion, the catheter defining a lumen; a selectively inflatable member in fluid communication with the lumen, wherein the selectively inflatable member is formed from a membrane having pores sized from about 10 Å to about 1μ and a pore density from about 10 4 pores/cm 2 to about 10 11 pores/cm 2 , further wherein the selectively inflatable member has a single chamber.
Claim 2
Independent Claim
94 words
An apparatus for delivering an agent to a treatment area using pressure, the apparatus not including phoretic delivery means, the apparatus comprising: a catheter having a distal portion and a proximal portion, the catheter defining a lumen; a selectively inflatable member in fluid communication with the lumen, wherein the selectively inflatable member is formed from a membrane having pores sized from about 10 Å to about 1μ and a pore density from about 10 4 pores/cm 2 to about 10 11 pores/cm 2 , further wherein the selectively inflatable member has a single chamber.
Claim 3
Dependent Claim
32 words
The apparatus of claim 1 wherein the membrane is arranged and configured to deliver the agent at a flux rate from about 0.001 ml/(min·cm 2 ·atm) to about 0.4 ml/(min·cm 2 ·atm).
Claim 4
Dependent Claim
32 words
The apparatus of claim 2 wherein the membrane is arranged and configured to deliver the agent at a flux rate from about 0.005 ml/(min·cm 2 ·atm) to about 0.1 ml/(min·cm 2 ·atm).
Claim 5
Dependent Claim
16 words
The apparatus of claim 1 wherein the pores are sized from about 0.05μ to about 1μ.
Claim 6
Dependent Claim
16 words
The apparatus of claim 4 wherein the pores are sized from about 0.08μ to about 0.5μ.
Claim 7
Dependent Claim
23 words
The apparatus of claim 1 wherein the pore density is from about 10 6 pores/cm 2 to about 10 9 pores/cm 2 .
Claim 8
Dependent Claim
32 words
The apparatus of claim 6 wherein the pores have a nominal size of about 0.05μ and a pore density from about 10 8 pores/cm 2 to about 10 9 pores/cm 2 .
Claim 9
Dependent Claim
32 words
The apparatus of claim 6 wherein the pores have a nominal size of about 0.1μ and a pore density from about 10 7 pores/cm 2 to about 10 8 pores/cm 2 .
Claim 10
Dependent Claim
32 words
The apparatus of claim 6 wherein the pores have a nominal size of about 0.2μ and a pore density from about 10 6 pores/cm 2 to about 10 7 pores/cm 2 .
Claim 11
Dependent Claim
18 words
The apparatus of claim 1 wherein the membrane that forms the selectively inflatable member is a continuous membrane.
Claim 12
Dependent Claim
14 words
The apparatus of claim 10 wherein the continuous membrane has a substantially uniform thickness.
Claim 13
Dependent Claim
11 words
The apparatus of claim 10 wherein the continuous membrane is seamless.
Claim 14
Dependent Claim
33 words
The apparatus of claim 12 wherein the continuous membrane has a portion that is substantially cylindrical and has oppositely disposed end portions, further wherein the oppositely disposed end portions tapper toward the catheter.
Claim 15
Dependent Claim
18 words
The apparatus of claim 13 wherein at least one of the oppositely disposed end portions is substantially impermeable.
Claim 16
Dependent Claim
26 words
The apparatus of claim 14 wherein both oppositely disposed end portions are substantially impermeable thereby causing the agent to be delivered in a substantially radial direction.
Claim 17
Independent Claim
109 words
An apparatus for delivering an agent to a treatment area, the apparatus comprising: a catheter having a distal portion and a proximal portion, the catheter defining a lumen; a selectively inflatable member in fluid communication with the lumen, wherein the selectively inflatable member is formed from a seamless and continuous membrane having pores sized from about 10 Å to about 1μ and has a pore density from about 10 4 pores/cm 2 to about 10 11 pores/cm 2 , further wherein the selectively inflatable member has a single chamber and oppositely disposed end portions, still further wherein at least one of the oppositely disposed end portions is substantially impermeable.
Claim 18
Independent Claim
109 words
An apparatus for delivering an agent to a treatment area, the apparatus comprising: a catheter having a distal portion and a proximal portion, the catheter defining a lumen; a selectively inflatable member in fluid communication with the lumen, wherein the selectively inflatable member is formed from a seamless and continuous membrane having pores sized from about 10 Å to about 1μ and has a pore density from about 10 4 pores/cm 2 to about 10 11 pores/cm 2 , further wherein the selectively inflatable member has a single chamber and oppositely disposed end portions, still further wherein at least one of the oppositely disposed end portions is substantially impermeable.
Claim 19
Independent Claim
133 words
An apparatus for delivering an agent to a treatment area, the apparatus comprising: a catheter having a distal portion and a proximal portion, the catheter defining a lumen; a selectively inflatable member in fluid communication with the lumen, wherein the selectively inflatable member is formed from a seamless and continuous membrane, has pores sized from about 10 Å to about 1μ, has a pore density from about 10 4 pores/cm 2 to about 10 11 pores/cm 2 , and is arranged and configured to deliver the agent at a flux rate from about 0.001 ml/(min·cm 2 ·atm) to about 0.4 ml/(min·cm 2 ·atm), further wherein the selectively inflatable member has a single chamber and oppositely disposed end portions, still further wherein at least one of the oppositely disposed end portions is substantially impermeable.
Claim 20
Independent Claim
133 words
An apparatus for delivering an agent to a treatment area, the apparatus comprising: a catheter having a distal portion and a proximal portion, the catheter defining a lumen; a selectively inflatable member in fluid communication with the lumen, wherein the selectively inflatable member is formed from a seamless and continuous membrane, has pores sized from about 10 Å to about 1μ, has a pore density from about 10 4 pores/cm 2 to about 10 11 pores/cm 2 , and is arranged and configured to deliver the agent at a flux rate from about 0.001 ml/(min·cm 2 ·atm) to about 0.4 ml/(min·cm 2 ·atm), further wherein the selectively inflatable member has a single chamber and oppositely disposed end portions, still further wherein at least one of the oppositely disposed end portions is substantially impermeable.
Claim 21
Independent Claim
140 words
An apparatus for delivering an agent to a treatment area, the apparatus comprising: a catheter having a distal portion and a proximal portion, the catheter defining a lumen; a selectively inflatable member in fluid communication with the lumen, wherein the selectively inflatable member is formed from a seamless membrane, the membrane having a portion that is substantially cylindrical, the substantially cylindrical portion having pores sized from about 10 Å to about 1μ, a pore density from about 10 4 pores/cm 2 to about 10 11 pores/cm 2 , further wherein the membrane is arranged and configured to deliver the agent at a flux rate from about 0.001 ml/(min·cm 2 ·atm) to about 0.4 ml/(min·cm 2 ·atm), still further wherein the selectively inflatable member has a single chamber and oppositely disposed end portions, the oppositely disposed end portions being substantially impermeable.
Claim 22
Independent Claim
140 words
An apparatus for delivering an agent to a treatment area, the apparatus comprising: a catheter having a distal portion and a proximal portion, the catheter defining a lumen; a selectively inflatable member in fluid communication with the lumen, wherein the selectively inflatable member is formed from a seamless membrane, the membrane having a portion that is substantially cylindrical, the substantially cylindrical portion having pores sized from about 10 Å to about 1μ, a pore density from about 10 4 pores/cm 2 to about 10 11 pores/cm 2 , further wherein the membrane is arranged and configured to deliver the agent at a flux rate from about 0.001 ml/(min·cm 2 ·atm) to about 0.4 ml/(min·cm 2 ·atm), still further wherein the selectively inflatable member has a single chamber and oppositely disposed end portions, the oppositely disposed end portions being substantially impermeable.
Claim 23
Independent Claim
134 words
An apparatus for delivering an agent to a treatment area, the apparatus comprising: a catheter having a distal portion and a proximal portion, the catheter defining a lumen; a selectively inflatable member in fluid communication with the lumen, wherein the selectively inflatable member is formed from a membrane having pores sized from about 10 Å to about 1μ and a pore density from about 10 4 pores/cm 2 to about 10 11 pores/cm 2 , the membrane being arranged and configured to deliver the agent at a flux rate from about 0.001 ml/(min·cm 2 ·atm) to about 0.4 ml/(min·cm 2 ·atm), further wherein the selectively inflatable member has a single chamber; and means confiqured to phoretically transport the agent from the chamber to the treatment area, the means being operably connected to the catheter.
Claim 24
Independent Claim
134 words
An apparatus for delivering an agent to a treatment area, the apparatus comprising: a catheter having a distal portion and a proximal portion, the catheter defining a lumen; a selectively inflatable member in fluid communication with the lumen, wherein the selectively inflatable member is formed from a membrane having pores sized from about 10 Å to about 1μ and a pore density from about 10 4 pores/cm 2 to about 10 11 pores/cm 2 , the membrane being arranged and configured to deliver the agent at a flux rate from about 0.001 ml/(min·cm 2 ·atm) to about 0.4 ml/(min·cm 2 ·atm), further wherein the selectively inflatable member has a single chamber; and means confiqured to phoretically transport the agent from the chamber to the treatment area, the means being operably connected to the catheter.
Claim 25
Dependent Claim
35 words
The apparatus of claim 19 wherein the means configured to phoretically transport the agent includes first and second electrodes configured to be connected to a power supply, the first electrode being positioned within the chamber.
Claim 26
Dependent Claim
22 words
The apparatus of claim 19 wherein the means configured to phoretically transport the agent includes an ultrasonic transducer positioned within the chamber.
Claim 27
Dependent Claim
32 words
The apparatus of claim 19 wherein the membrane is arranged and configured to deliver the agent at a flux rate from about 0.005 ml/(min·cm 2 ·atm) to about 0.1 ml/(min·cm 2 ·atm).
Claim 28
Dependent Claim
18 words
The apparatus of claim 19 wherein the membrane that forms the selectively inflatable member is a continuous membrane.
Claim 29
Dependent Claim
14 words
The apparatus of claim 23 wherein the continuous membrane has a substantially uniform thickness.
Claim 30
Dependent Claim
11 words
The apparatus of claim 23 wherein the continuous membrane is seamless.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-10-29 | 2000-04-29 | 2000-10-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-10-29 | 2004-04-29 | 2004-10-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-10-29 | 2008-04-29 | 2008-10-29 | $7700.00 | Window Closed / Lapsed |