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US5558094B1 Expired / Lapsed US ⏱️ 0.0 years remaining

Methods for using persistent gases as ultrasound contrast media

Assignee: GE Healthcare Ltd
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Filing: 1995-02-01
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Granted: 1999-01-19
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Expires: 2015-02-01
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Abstract

Abstract Disclosed herein are agents for enhancing the contrast in an ultrasound image. These agents are extremely small bubbles, or "microbubbles," comprised of specially selected gases. The microbubbles described herein exhibit long life spans in solution and may be produced at a size small enough to traverse the lungs, thus enabling improved ultrasound imaging of the cardiovascular system and other vital organs. Also disclosed herein is a method for selecting gases from which contrast agents may be produced. The method is based on calculations using inherent physical properties of gases and describes a means to associate the properties of a gas with the time for dissolution of microbubbles comprised of the gas.

Inventors

  • 👤 Steven M Quay

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 16:51
CPC Classifications
A; A61; A61K; A61K49/00; A61K49/22; A61K49/222; A61K49/223

Claims Analysis

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2002-01-18 2002-07-20 2003-01-19 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2006-01-18 2006-07-20 2007-01-19 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2010-01-18 2010-07-20 2011-01-19 $7700.00 Window Closed / Lapsed

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