US5539311A
Expired / Lapsed
US
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Method for reducing artifacts in magnetic resonance imaging
Assignee: Hitachi Healthcare Manufacturing Ltd
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Filing: 1993-12-03
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Granted: 1996-07-23
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Expires: 2013-12-03
Abstract
Abstract In magnetic resonance imaging, a first echo train is obtained by applying a readout gradient magnetic field to a region of interest to be imaged and periodically inverting the polarity of the readout gradient magnetic field, without applying an encoding gradient magnetic field to the region of interest. A periodic change of phase shift of the first echo train is detected from the first echo train. Information indicating phase shifts of all of the echoes in the first echo train is obtained using the periodic change of phase shift. A second echo train is obtained by applying a readout gradient magnetic field and an encoding magnetic field to the region of interest and periodically inverting the polarity of the readout gradient magnetic field. Phases of echoes in the second echo train are corrected using the information indicating phase shifts of all of the echoes in the first echo train.
Inventors
- 👤 Kenji Takiguchi
- 👤 Hiroyuki Itagaki
- 👤 Hidemi Shiono
- 👤 Etsuji Yamamoto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 08:17
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/54; G01R33/56; G01R33/565; G01R33/56554
Claims Analysis
Total Claims: 36
Claim 1
Independent Claim
200 words
A method for reducing artifacts in magnetic resonance imaging comprising the steps of: generating a first echo train by applying a readout gradient magnetic field in a first direction by inverting a polarity of the readout gradient magnetic field after selectively exciting a region of interest to be imaged; obtaining information indicating phase shifts of echoes from at least a part of the generated first echo train; generating a second echo train by applying the readout gradient magnetic field in said first direction by inverting the polarity of the readout gradient magnetic field after selectively exciting said region of interest to be imaged once again and by applying an encoding gradient magnetic field in a second direction perpendicular to said first direction; and correcting a phase of at least one echo in the generated second echo train on the basis of said information indicating the phase shifts of echoes; wherein a periodic change of phase shift of said first echo train is detected from a part of said first echo train and furthermore information indicating the phase shifts of all the echoes in said first echo train is obtained on the basis of the detected periodic change of phase shift.
Claim 2
Independent Claim
200 words
A method for reducing artifacts in magnetic resonance imaging comprising the steps of: generating a first echo train by applying a readout gradient magnetic field in a first direction by inverting a polarity of the readout gradient magnetic field after selectively exciting a region of interest to be imaged; obtaining information indicating phase shifts of echoes from at least a part of the generated first echo train; generating a second echo train by applying the readout gradient magnetic field in said first direction by inverting the polarity of the readout gradient magnetic field after selectively exciting said region of interest to be imaged once again and by applying an encoding gradient magnetic field in a second direction perpendicular to said first direction; and correcting a phase of at least one echo in the generated second echo train on the basis of said information indicating the phase shifts of echoes; wherein a periodic change of phase shift of said first echo train is detected from a part of said first echo train and furthermore information indicating the phase shifts of all the echoes in said first echo train is obtained on the basis of the detected periodic change of phase shift.
Claim 3
Dependent Claim
125 words
A method according to claim 1, wherein after generating said first echo train, applying the readout gradient magnetic field in said first direction by inverting the polarity of the readout gradient magnetic field after selectively exciting said region of interest to be imaged once again and applying the encoding gradient magnetic field in said second direction are repeated a plurality of times so that a plurality of second echo trains are generated; wherein the phase of at least one echo in each train of the generated plurality of second echo trains is corrected on the basis of said information indicating the phase shifts of echoes; and wherein an initial amplitude of said encoding gradient magnetic field is changed every repetition of said plurality of times.
Claim 4
Dependent Claim
66 words
A method according to claim 2, wherein after said region of interest to be imaged is selectively excited, an inversion radio frequency pulse is applied in said region of interest so that a polarity of magnetization in said region of interest is inverted, and then said readout gradient magnetic field is applied or said readout gradient magnetic field and said encoding gradient magnetic field are applied.
Claim 5
Dependent Claim
66 words
A method according to claim 1, wherein after said region of interest to be imaged is selectively excited, an inversion radio frequency pulse is applied in said region of interest so that a polarity of magnetization in said region of interest is inverted, and then said readout gradient magnetic field is applied or said readout gradient magnetic field and said encoding gradient magnetic field are applied.
Claim 6
Dependent Claim
32 words
A method according to claim 1, wherein the periodic change of phase shift of the first echo train is detected from a region of high signal level in the first echo train.
Claim 7
Dependent Claim
32 words
A method according to claim 1, wherein the periodic change of phase shift of the first echo train is detected from a phase difference between neighboring echoes in the first echo train.
Claim 8
Dependent Claim
75 words
A method according to claim 1, wherein the first echo train includes a first group of echoes generated when the polarity of the readout gradient magnetic field is positive, and a second group of echoes generated when the polarity of the readout gradient magnetic field is negative; and wherein the periodic change of phase shift of the first echo train is detected separately from the first group of echoes and the second group of echoes.
Claim 9
Dependent Claim
44 words
A method according to claim 1, wherein the first echo train includes a front part and a rear part; and wherein the periodic change of phase shift of the first echo train is detected from only the front part of the first echo train.
Claim 10
Independent Claim
216 words
A method of magnetic resonance imaging comprising the steps of: generating a first echo train by applying a readout gradient magnetic field in a first direction by inverting a polarity of the readout gradient magnetic field after selectively exciting a region of interest to be imaged; obtaining information indicating phase shifts of echoes from at least a part of the generated first echo train; generating a second echo train by applying the readout gradient magnetic field in said first direction by inverting the polarity of the readout gradient magnetic field after selectively exciting said region of interest to be imaged once again and by applying an encoding gradient magnetic field in a second direction perpendicular to said first direction; correcting a phase of at least one echo in the generated second echo train on the basis of said information indicating the phase shifts of echoes; and reconstructing an image from the second echo train in which the phase of at least one echo is corrected; wherein a periodic change of phase shift of said first echo train is detected from a part of said first echo train and furthermore information indicating the phase shifts of all the echoes in said first echo train is obtained on the basis of the detected periodic change of phase shift.
Claim 11
Independent Claim
216 words
A method of magnetic resonance imaging comprising the steps of: generating a first echo train by applying a readout gradient magnetic field in a first direction by inverting a polarity of the readout gradient magnetic field after selectively exciting a region of interest to be imaged; obtaining information indicating phase shifts of echoes from at least a part of the generated first echo train; generating a second echo train by applying the readout gradient magnetic field in said first direction by inverting the polarity of the readout gradient magnetic field after selectively exciting said region of interest to be imaged once again and by applying an encoding gradient magnetic field in a second direction perpendicular to said first direction; correcting a phase of at least one echo in the generated second echo train on the basis of said information indicating the phase shifts of echoes; and reconstructing an image from the second echo train in which the phase of at least one echo is corrected; wherein a periodic change of phase shift of said first echo train is detected from a part of said first echo train and furthermore information indicating the phase shifts of all the echoes in said first echo train is obtained on the basis of the detected periodic change of phase shift.
Claim 12
Dependent Claim
151 words
A method according to claim 9, wherein after generating said first echo train, applying the readout gradient magnetic field in said first direction by inverting the polarity of the readout gradient magnetic field after selectively exciting said region of interest to be imaged once again and applying the encoding gradient magnetic field in said second direction are repeated a plurality of times so that a plurality of second echo trains are generated; wherein the phase of at least one echo in each train of the generated plurality of second echo trains is corrected on the basis of said information indicating the phase shifts of echoes; wherein an image is reconstructed from the plurality of second echo trains in which the phase of at least one echo in each train is corrected; and wherein an initial amplitude of said encoding gradient magnetic field is changed every repetition of said plurality of times.
Claim 13
Dependent Claim
66 words
A method according to claim 10, wherein after said region of interest to be imaged is selectively excited, an inversion radio frequency pulse is applied in said region of interest so that a polarity of magnetization in said region of interest is inverted, and then said readout gradient magnetic field is applied or said readout gradient magnetic field and said encoding gradient magnetic field are applied.
Claim 14
Dependent Claim
66 words
A method according to claim 9, wherein after said region of interest to be imaged is selectively excited, an inversion radio frequency pulse is applied in said region of interest so that a polarity of magnetization in said region of interest is inverted, and then said readout gradient magnetic field is applied or said readout gradient magnetic field and said encoding gradient magnetic field are applied.
Claim 15
Dependent Claim
32 words
A method according to claim 9, wherein the periodic change of phase shift of the first echo train is detected from a region of high signal level in the first echo train.
Claim 16
Dependent Claim
32 words
A method according to claim 9, wherein the periodic change of phase shift of the first echo train is detected from a phase difference between neighboring echoes in the first echo train.
Claim 17
Dependent Claim
75 words
A method according to claim 9, wherein the first echo train includes a first group of echoes generated when the polarity of the readout gradient magnetic field is positive, and a second group of echoes generated when the polarity of the readout gradient magnetic field is negative; and wherein the periodic change of phase shift of the first echo train is detected separately from the first group of echoes and the second group of echoes.
Claim 18
Dependent Claim
44 words
A method according to claim 9, wherein the first echo train includes a front part and a rear part; and wherein the periodic change of phase shift of the first echo train is detected from only the front part of the first echo train.
Claim 19
Independent Claim
221 words
A method for reducing artifacts in magnetic resonance imaging comprising the steps of: selectively exciting a region of interest to be imaged a first time; generating a first echo train including a plurality of echoes from the region of interest by applying to the region of interest a readout gradient magnetic field having an intensity gradient in a first direction and periodically inverting a polarity of the readout gradient magnetic field; detecting a periodic change of phase shift of the first echo train from only a part of the first echo train; obtaining information indicating phase shifts of all of the echoes in the first echo train using the periodic change of phase shift; selectively exciting the region of interest a second time; generating a second echo train including a plurality of echoes from the region of interest by applying to the region of interest a readout gradient magnetic field having an intensity gradient in the first direction and periodically inverting a polarity of the readout gradient magnetic field, and an encoding gradient magnetic field having an intensity gradient in a second direction perpendicular to the first direction; and correcting a phase of at least one of the echoes in the second echo train based on the information indicating phase shifts of all of the echoes in the first echo train.
Claim 20
Independent Claim
221 words
A method for reducing artifacts in magnetic resonance imaging comprising the steps of: selectively exciting a region of interest to be imaged a first time; generating a first echo train including a plurality of echoes from the region of interest by applying to the region of interest a readout gradient magnetic field having an intensity gradient in a first direction and periodically inverting a polarity of the readout gradient magnetic field; detecting a periodic change of phase shift of the first echo train from only a part of the first echo train; obtaining information indicating phase shifts of all of the echoes in the first echo train using the periodic change of phase shift; selectively exciting the region of interest a second time; generating a second echo train including a plurality of echoes from the region of interest by applying to the region of interest a readout gradient magnetic field having an intensity gradient in the first direction and periodically inverting a polarity of the readout gradient magnetic field, and an encoding gradient magnetic field having an intensity gradient in a second direction perpendicular to the first direction; and correcting a phase of at least one of the echoes in the second echo train based on the information indicating phase shifts of all of the echoes in the first echo train.
Claim 21
Dependent Claim
111 words
A method according to claim 17, wherein the steps of selectively exciting the region of interest a second time, generating a second echo train, and correcting a phase of at least one of the echoes in the second echo train are repeated a plurality of times, thereby generating a plurality of second echo trains in each of which the phase of at least one of the echoes is corrected based on the information indicating phase shifts of all of the echoes in the first echo train; and wherein an initial amplitude of the encoding gradient magnetic field is changed before each repetition of the step of generating a second echo train.
Claim 22
Dependent Claim
124 words
A method according to claim 18, further comprising the steps of: applying an inversion radio frequency pulse to the region of interest to invert a polarity of magnetization in the region of interest between the step of selectively exciting the region of interest a first time and the step of generating a first echo train; and applying an inversion radio frequency pulse to the region of interest to invert a polarity of magnetization in the region of interest between the step of selectively exciting the region of interest a second time and the step of generating least one second echo train each time the steps of selectively exciting the region of interest a second time and generating least one second echo train are performed.
Claim 23
Dependent Claim
100 words
A method according to claim 17, further comprising the steps of: applying an inversion radio frequency pulse to the region of interest to invert a polarity of magnetization in the region of interest between the step of selectively exciting the region of interest a first time and the step of generating a first echo train; and applying an inversion radio frequency pulse to the region of interest to invert a polarity of magnetization in the region of interest between the step of selectively exciting the region of interest a second time and the step of generating a second echo train.
Claim 24
Dependent Claim
66 words
A method according to claim 17, wherein the first echo train includes a high signal level region in which echoes have relatively high signal levels, and a low signal level region in which echoes have relatively low signal levels; and wherein the periodic change of phase shift of the first echo train is detected from only the high signal level region of the first echo train.
Claim 25
Dependent Claim
31 words
A method according to claim 17, wherein the periodic change of phase shift is detected from a phase difference between neighboring echoes in only a part of the first echo train.
Claim 26
Dependent Claim
75 words
A method according to claim 17, wherein the first echo train includes a first group of echoes generated when the polarity of the readout gradient magnetic field is positive, and a second group of echoes generated when the polarity of the readout gradient magnetic field is negative; and wherein the periodic change of phase shift of the first echo train is detected separately from the first group of echoes and the second group of echoes.
Claim 27
Dependent Claim
44 words
A method according to claim 17, wherein the first echo train includes a front part and a rear part; and wherein the periodic change of phase shift of the first echo train is detected from only the front part of the first echo train.
Claim 28
Independent Claim
239 words
A method of magnetic resonance imaging comprising the steps of: selectively exciting a region of interest to be imaged a first time; generating a first echo train including a plurality of echoes from the region of interest by applying to the region of interest a readout gradient magnetic field having an intensity gradient in a first direction and periodically inverting a polarity of the readout gradient magnetic field; detecting a periodic change of phase shift of the first echo train from only a part of the first echo train; obtaining information indicating phase shifts of all of the echoes in the first echo train using the periodic change of phase shift; selectively exciting the region of interest a second time; generating a second echo train including a plurality of echoes from the region of interest by applying to the region of interest a readout gradient magnetic field having an intensity gradient in the first direction and periodically inverting a polarity of the readout gradient magnetic field, and an encoding gradient magnetic field having an intensity gradient in a second direction perpendicular to the first direction; correcting a phase of at least one of the echoes in the second echo train based on the information indicating phase shifts of all of the echoes in the first echo train; and reconstructing an image from the second echo train in which the phase of at least one of the echoes is corrected.
Claim 29
Independent Claim
239 words
A method of magnetic resonance imaging comprising the steps of: selectively exciting a region of interest to be imaged a first time; generating a first echo train including a plurality of echoes from the region of interest by applying to the region of interest a readout gradient magnetic field having an intensity gradient in a first direction and periodically inverting a polarity of the readout gradient magnetic field; detecting a periodic change of phase shift of the first echo train from only a part of the first echo train; obtaining information indicating phase shifts of all of the echoes in the first echo train using the periodic change of phase shift; selectively exciting the region of interest a second time; generating a second echo train including a plurality of echoes from the region of interest by applying to the region of interest a readout gradient magnetic field having an intensity gradient in the first direction and periodically inverting a polarity of the readout gradient magnetic field, and an encoding gradient magnetic field having an intensity gradient in a second direction perpendicular to the first direction; correcting a phase of at least one of the echoes in the second echo train based on the information indicating phase shifts of all of the echoes in the first echo train; and reconstructing an image from the second echo train in which the phase of at least one of the echoes is corrected.
Claim 30
Dependent Claim
136 words
A method according to claim 25, wherein the steps of selectively exciting the region of interest a second time, generating a second echo train, and correcting a phase of at least one of the echoes in the second echo train are repeated a plurality of times, thereby generating a plurality of second echo trains in each of which the phase of at least one of the echoes is corrected based on the information indicating phase shifts of all of the echoes in the first echo train; wherein an initial amplitude of the encoding gradient magnetic field is changed before each repetition of the step of generating a second echo train; and wherein the image is reconstructed from the plurality of second echo trains in which the phase of at least one of the echoes is corrected.
Claim 31
Dependent Claim
124 words
A method according to claim 26, further comprising the steps of: applying an inversion radio frequency pulse to the region of interest to invert a polarity of magnetization in the region of interest between the step of selectively exciting the region of interest a first time and the step of generating a first echo train; and applying an inversion radio frequency pulse to the region of interest to invert a polarity of magnetization in the region of interest between the step of selectively exciting the region of interest a second time and the step of generating least one second echo train each time the steps of selectively exciting the region of interest a second time and generating least one second echo train are performed.
Claim 32
Dependent Claim
100 words
A method according to claim 25, further comprising the steps of: applying an inversion radio frequency pulse to the region of interest to invert a polarity of magnetization in the region of interest between the step of selectively exciting the region of interest a first time and the step of generating a first echo train; and applying an inversion radio frequency pulse to the region of interest to invert a polarity of magnetization in the region of interest between the step of selectively exciting the region of interest a second time and the step of generating a second echo train.
Claim 33
Dependent Claim
66 words
A method according to claim 25, wherein the first echo train includes a high signal level region in which echoes have relatively high signal levels, and a low signal level region in which echoes have relatively low signal levels; and wherein the periodic change of phase shift of the first echo train is detected from only the high signal level region of the first echo train.
Claim 34
Dependent Claim
31 words
A method according to claim 25, wherein the periodic change of phase shift is detected from a phase difference between neighboring echoes in only a part of the first echo train.
Claim 35
Dependent Claim
75 words
A method according to claim 25, wherein the first echo train includes a first group of echoes generated when the polarity of the readout gradient magnetic field is positive, and a second group of echoes generated when the polarity of the readout gradient magnetic field is negative; and wherein the periodic change of phase shift of the first echo train is detected separately from the first group of echoes and the second group of echoes.
Claim 36
Dependent Claim
44 words
A method according to claim 25, wherein the first echo train includes a front part and a rear part; and wherein the periodic change of phase shift of the first echo train is detected from only the front part of the first echo train.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-07-23 | 2000-01-22 | 2000-07-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-07-23 | 2004-01-22 | 2004-07-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-07-23 | 2008-01-22 | 2008-07-23 | $7700.00 | Window Closed / Lapsed |