US5538694A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device for simultaneously or sequentially carrying out chemical reactions
Assignee: German Cancer Research Center
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Filing: 1993-02-27
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Granted: 1996-07-23
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Expires: 2013-02-27
Abstract
Abstract A device for simultaneously or sequentially carrying out chemical reactionsncludes a stack of four rods; and a carrier plate which is displaceable. The stack of four rods is composed of a first rod which has a position which is fixed and which has a plurality of throughgoing bores defined therein; a second rod which is in contact with the first rod, which is fixedly connected to the carrier plate so that the second rod is displaceable, and which has a throughgoing bore defined therethrough; a third rod which is in contact with the second rod, which is disposed so that it is displaceable by the carrier plate, arid which has defined therein a plurality of reaction chambers which are provided with two openings located opposite one another and which are present in a number n; and a fourth rod which is in contact with the third rod, which is fixedly connected to the carrier plate, and which has a throughgoing bore defined therein. The openings of the reaction chambers of the third rod and the throughgoing bores of all least one of the first, second, and fourth rods are positionable so that a plurality of positions are provided by means of displacing the rods with respect to one another in which a throughgoing connection is produced which extends through the stack of rods and comprises a reaction chamber and at least one throughgoing bore of the first, second and fourth rods.
Inventors
- 👤 Hajo Delius
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 19:35
CPC Classifications
C; C07; C07K; C07K1/00; C07K1/04; C07K1/045; B; B01; B01J; B01J19/00; B01J19/0046; B01J2219/00; B01J2219/00274; B01J2219/00277; B01J2219/00279; B01J2219/00306; B01J2219/00313; B01J2219/00319; B01J2219/00324; B01J2219/00328; B01J2219/00351; B01J2219/00353; B01J2219/00414; B01J2219/00418; B01J2219/00423; B01J2219/00497; B01J2219/005; B01J2219/00583; B01J2219/00585; B01J2219/0059; B01J2219/00596; B01J2219/0068; B01J2219/00686; B01J2219/00689; B01J2219/00718; B01J2219/0072; B01J2219/00722; C40; C40B; C40B40/00; C40B40/04; C40B40/06; C40B60/00; C40B60/14
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
321 words
A device for one of simultaneously or sequentially carrying out chemical reactions, comprising: a stack of four rods which has a longitudinal axis and in which the four rods are disposed on parallel and in sequentially stacked contact with one another, only one of which four rods includes reaction chambers defined therein, and three of which four rods are displaceable along the longitudinal axis of the stack; and a carrier plate which is displaceable along an axis which is parallel to the longitudinal axis of the stack, wherein the stack of four rods is comprised of: a first rod which has a position which is fixed and which has a plurality of throughgoing bores defined therein; a second rod which is in contact with the first rod, which is fixedly connected to the carrier plate so that the second rod is displaceable relative to the first rod, and which has a throughgoing bore defined therethrough; a third rod which is in contact with the second rod, which is disposed so that it is displaceable by the carrier plate, and which has defined therein a plurality of reaction chambers which are provided with two openings located opposite one another and which are present in a number n; and a fourth rod which is in contact with the third rod, which is fixedly connected to the carrier plate, and which has a throughgoing bore defined therein, and wherein the openings of respective ones of the reaction chambers of the third rod and the throughgoing bores of at least one of the first, second, and fourth rods are positionable so that a plurality of positions are provided by means of displacing the rods with respect to one another in which a throughgoing connection is produced which extends through the stack of rods and comprises a reaction chamber of the third rod and at least one throughgoing bore of the first, second and fourth rods.
Claim 2
Independent Claim
321 words
A device for one of simultaneously or sequentially carrying out chemical reactions, comprising: a stack of four rods which has a longitudinal axis and in which the four rods are disposed on parallel and in sequentially stacked contact with one another, only one of which four rods includes reaction chambers defined therein, and three of which four rods are displaceable along the longitudinal axis of the stack; and a carrier plate which is displaceable along an axis which is parallel to the longitudinal axis of the stack, wherein the stack of four rods is comprised of: a first rod which has a position which is fixed and which has a plurality of throughgoing bores defined therein; a second rod which is in contact with the first rod, which is fixedly connected to the carrier plate so that the second rod is displaceable relative to the first rod, and which has a throughgoing bore defined therethrough; a third rod which is in contact with the second rod, which is disposed so that it is displaceable by the carrier plate, and which has defined therein a plurality of reaction chambers which are provided with two openings located opposite one another and which are present in a number n; and a fourth rod which is in contact with the third rod, which is fixedly connected to the carrier plate, and which has a throughgoing bore defined therein, and wherein the openings of respective ones of the reaction chambers of the third rod and the throughgoing bores of at least one of the first, second, and fourth rods are positionable so that a plurality of positions are provided by means of displacing the rods with respect to one another in which a throughgoing connection is produced which extends through the stack of rods and comprises a reaction chamber of the third rod and at least one throughgoing bore of the first, second and fourth rods.
Claim 3
Dependent Claim
55 words
The device according to claim 1, wherein the third rod has a plurality of different positions having a number n relative to the second and fourth rods in which the throughgoing bores of the second and fourth rods and the openings of one of the reaction chambers of the third rod produce a throughgoing connection.
Claim 4
Dependent Claim
16 words
The device according to claim 1, wherein the third rod has defined therein a throughgoing bore.
Claim 5
Dependent Claim
96 words
The device according to claim 1, wherein the plurality of throughgoing bores defined in the first rod are spaced apart by a predetermined distance, wherein the respective openings of the reaction chambers in the third rod are spaced apart by a predetermined distance, and wherein the predetermined distance by which the plurality of throughgoing bores defined in the first rod are spaced apart and the predetermined distance by which the respective openings of the reaction chambers in the third rod are spaced apart are the same so that an alignment produces a throughgoing connection thereof respectively.
Claim 6
Dependent Claim
77 words
The device according to claim 4, wherein the third rod has defined therein a throughgoing bore which is disposed at a predetermined distance from the respective two openings located opposite one another of one of the reaction chambers of the third rod, and wherein the predetermined distance of the throughgoing bore of the third rod and the predetermined distance by which the openings of the reaction chambers in the third rod are spaced apart is the same.
Claim 7
Dependent Claim
34 words
The device according to claim 1, wherein the respective throughgoing bores of the second and the fourth rods extend perpendicular to the longitudinal axis of the stack and lie on a common straight line.
Claim 8
Dependent Claim
37 words
The device according to claim 1, further comprising a plurality of reagent lines, and wherein the plurality of throughgoing bores of the first rod are respectively connected in a liquid-tight manner with the plurality of reagent lines.
Claim 9
Dependent Claim
68 words
The device according to claim 1, further comprising a first stepping motor for moving the carrier plate along an axis which is parallel to the stack, and wherein the third rod is displaced by the carrier plate so that the throughgoing bores of the second and fourth rods are aligned with the two openings of one of the reaction chambers, the two openings being located opposite one another.
Claim 10
Dependent Claim
26 words
The device according to claim 8, further comprising a second stepping motor for moving the third rod along an axis which is parallel to the stack.
Claim 11
Dependent Claim
25 words
The device according to claim 9, wherein at least one of the first stepping motor and the second stepping motor are controlled by a computer.
Claim 12
Dependent Claim
63 words
The device according to claim 1, further comprising at least one stop, and wherein the third rod is displaced by the carrier plate and abuts one of the at least one stop so that the throughgoing bores of the second and fourth rods are aligned with the two openings of one of the reaction chambers, the two openings being located opposite one another.
Claim 13
Dependent Claim
26 words
The device according to claim 11, further comprising a second stepping motor for moving the third rod along an axis which is parallel to the stack.
Claim 14
Dependent Claim
16 words
The device according to claim 12, wherein the second stepping motor is controlled by a computer.
Claim 15
Dependent Claim
29 words
The device according to claim 1, wherein the four rods are made of a material selected from the group consisting of a metal, a plastic, and a machinable glass.
Claim 16
Dependent Claim
34 words
The device according to claim 14, wherein the four rods are in contact with a one another by way of contact surfaces that are machined to be planar and that effect a liquid-tight seal.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-07-23 | 2000-01-22 | 2000-07-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-07-23 | 2004-01-22 | 2004-07-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-07-23 | 2008-01-22 | 2008-07-23 | $7700.00 | Window Closed / Lapsed |