US5531772A
Expired / Lapsed
US
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Rate responsive cardiac pacemaker with filtered impedance sensing and method
Assignee: Intermedics Inc
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Filing: 1994-11-18
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Granted: 1996-07-02
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Expires: 2014-11-18
Abstract
Abstract An implantable, rate responsive pacemaker, sensitive to impedance changes in the heart as an indicator of cardiac stroke volume, wherein common interfering signals such as the intracardiac electrogram, myoelectric signals, pacing artifacts and pacing after-potentials are eliminated from the measurement of impedance. The cardiac pacemaker senses varying impedance of the heart by discharging an active capacitor through an electrode implanted within the heart to a second electrode or to the case or can of the pacemaker. The active capacitor is discharged for a selected short period of time after which the voltage remaining on the capacitor is measured. To minimize error in the measurement of voltage discharged from the active capacitor, the selected short period of time for discharge can be varied dynamically by the cardiac pacemaker. Prior to discharge of this active capacitor, however, the cardiac pacemaker samples the electrical condition of the heart or the body of the patient between the two electrodes by charging a passive capacitor. The sampled voltage on the passive capacitor is subtracted from the residual voltage on the active capacitor and the resulting voltage is used to adjust the rate of the pacemaker.
Inventors
- 👤 David Prutchi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 13:49
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/362; A61N1/365; A61N1/36514; A61N1/36521
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
133 words
A cardiac stimulation apparatus comprising means for pacing a patient's heart; means for measuring impedance within the patient's body, said impedance measuring means including means for sampling an intrinsic voltage condition of the patient's body at at least one location within the patient's body and for producing a first signal correlated to said intrinsic voltage condition, means for applying an electric current between at least two points on said apparatus, means for sensing a voltage in response to the application of said electrical current and for producing a second signal correlated to said voltage, and means for combining said first and second signals to produce a combined signal; means for deriving a metabolic demand parameter from said combined signal; and means for adjusting a pacing parameter in relation to said metabolic demand parameter.
Claim 2
Dependent Claim
133 words
A cardiac stimulation apparatus comprising means for pacing a patient's heart; means for measuring impedance within the patient's body, said impedance measuring means including means for sampling an intrinsic voltage condition of the patient's body at at least one location within the patient's body and for producing a first signal correlated to said intrinsic voltage condition, means for applying an electric current between at least two points on said apparatus, means for sensing a voltage in response to the application of said electrical current and for producing a second signal correlated to said voltage, and means for combining said first and second signals to produce a combined signal; means for deriving a metabolic demand parameter from said combined signal; and means for adjusting a pacing parameter in relation to said metabolic demand parameter.
Claim 3
Dependent Claim
57 words
The cardiac stimulation apparatus according to claim 1 wherein said means for measuring impedance further comprises timing means for controlling said means for sampling to sample said intrinsic voltage condition during a first pre-determined time and for controlling said means for applying said electric current to apply said electric current during a second pre-determined period of time.
Claim 4
Dependent Claim
29 words
The cardiac stimulation apparatus according to claim 2 wherein said means for combining said first and second signals comprises means for subtracting said second signal from said first signal.
Claim 5
Dependent Claim
58 words
The cardiac stimulation apparatus according to claim 3 further comprising means for sensing a second parameter correlated to physiologic need of said patient and wherein said means for determining said pacing parameter in relation to said metabolic demand parameter further comprises means for determining said pacing parameter in relation to both said demand parameter and said second parameter.
Claim 6
Dependent Claim
29 words
The cardiac stimulation apparatus according to claim 1 wherein said means for combining said first and second signals comprises means for subtracting said second signal from said first signal.
Claim 7
Dependent Claim
58 words
The cardiac stimulation apparatus according to claim 5 further comprising means for sensing a second parameter correlated to physiologic need of said patient and wherein said means for determining said pacing parameter in relation to said metabolic demand parameter further comprises means for determining said pacing parameter in relation to both said demand parameter and said second parameter.
Claim 8
Dependent Claim
58 words
The cardiac stimulation apparatus according to claim 1 further comprising means for sensing a second parameter correlated to physiologic need of said patient and wherein said means for determining said pacing parameter in relation to said metabolic demand parameter further comprises means for determining said pacing parameter in relation to both said demand parameter and said second parameter.
Claim 9
Dependent Claim
17 words
The cardiac stimulation apparatus according to claim 1 wherein said means for sampling comprises a passive capacitor.
Claim 10
Dependent Claim
23 words
The cardiac stimulation apparatus according to claim 8 wherein said means for sampling further comprises a buffer and a sample and hold circuit.
Claim 11
Dependent Claim
57 words
The cardiac stimulation apparatus according to claim 9 wherein said means for measuring impedance further comprises timing means for controlling said means for sampling to sample said intrinsic voltage condition during a first pre-determined time and for controlling said means for applying said electric current to apply said electric current during a second pre-determined period of time.
Claim 12
Dependent Claim
29 words
The cardiac stimulation apparatus according to claim 10 wherein said means for combining said first and second signals comprises means for subtracting said second signal from said first signal.
Claim 13
Dependent Claim
25 words
The cardiac stimulation apparatus according to claim 11 wherein said means for combining said first and second signals further comprises a sample and hold circuit.
Claim 14
Dependent Claim
58 words
The cardiac stimulation apparatus according to claim 12 further comprising means for sensing a second parameter correlated to physiologic need of said patient and wherein said means for determining said pacing parameter in relation to said metabolic demand parameter further comprises means for determining said pacing parameter in relation to both said demand parameter and said second parameter.
Claim 15
Dependent Claim
80 words
The cardiac stimulation apparatus according to claim 1 wherein said means for applying an electric current further comprises means for variably controlling a length of time during which said electric current is applied and wherein said means for sensing a voltage in response to the application of said electric current is responsive to sample said voltage at the end of said length of time and wherein said cardiac stimulation apparatus further comprises means for dynamically adjusting said length of time.
Claim 16
Dependent Claim
50 words
The cardiac stimulation apparatus according to claim 14 wherein said means for applying an electric current comprises an active capacitance and said means for dynamically adjusting said length of time comprises means for setting said length of time as a function of said active capacitance and said metabolic demand parameter.
Claim 17
Dependent Claim
48 words
The cardiac stimulation apparatus according to claim 15 wherein said means for setting said length of time comprise means for setting said length of time to a length of time substantially equal to a product of said active capacitance and a rolling average of said metabolic demand parameter.
Claim 18
Independent Claim
113 words
A method for controlling a cardiac stimulation apparatus for pacing a patient's heart at a controlled rate comprising the steps of: sampling an intrinsic voltage condition of the patient's body at at least one location within the patient's body, producing a first signal correlated to said intrinsic voltage condition, applying an electric current between at least two points on said apparatus, sensing a voltage in response to the application of said electrical current producing a second signal correlated to said voltage, combining said first and second signals to produce a combined signal; deriving a metabolic demand parameter from said combined signal; and determining said controlled rate in relation to said metabolic demand parameter.
Claim 19
Independent Claim
113 words
A method for controlling a cardiac stimulation apparatus for pacing a patient's heart at a controlled rate comprising the steps of: sampling an intrinsic voltage condition of the patient's body at at least one location within the patient's body, producing a first signal correlated to said intrinsic voltage condition, applying an electric current between at least two points on said apparatus, sensing a voltage in response to the application of said electrical current producing a second signal correlated to said voltage, combining said first and second signals to produce a combined signal; deriving a metabolic demand parameter from said combined signal; and determining said controlled rate in relation to said metabolic demand parameter.
Claim 20
Dependent Claim
45 words
The method according to claim 17 further comprising timing said step of sampling to sample said intrinsic voltage condition during a first pre-determined time, and timing said step of applying said electric current to apply said electric current during a second pre-determined period of time.
Claim 21
Dependent Claim
25 words
The method according to claim 18 wherein said step of combining said first and second signals comprises subtracting said second signal from said first signal.
Claim 22
Dependent Claim
47 words
The method according to claim 19 further comprising sensing a second parameter correlated to physiologic need of said patient and wherein said step of determining said controlled rate in relation to said metabolic demand parameter further comprises determining said controlled rate in relation to both said parameters.
Claim 23
Dependent Claim
25 words
The method according to claim 17 wherein said step of combining said first and second signals comprises subtracting said second signal from said first signal.
Claim 24
Dependent Claim
47 words
The method according to claim 21 further comprising sensing a second parameter correlated to physiologic need of said patient and wherein said step of determining said controlled rate in relation to said metabolic demand parameter further comprises determining said controlled rate in relation to both said parameters.
Claim 25
Dependent Claim
47 words
The method according to claim 17 further comprising sensing a second parameter correlated to physiologic need of said patient and wherein said step of determining said controlled rate in relation to said metabolic demand parameter further comprises determining said controlled rate in relation to both said parameters.
Claim 26
Dependent Claim
137 words
A cardiac stimulation apparatus comprising means for pacing a patient's heart; means for measuring impedance within the patient's body, said impedance measuring means including means for applying an electric current between at least two points on said apparatus, said means for applying an electric current further having means for variably controlling a length of time during which said electric current is applied, means for periodically and automatically adjusting said length of time to minimize measuring error, and means for sensing a voltage in response to the application of said electrical current responsive to sample said voltage at the end of said length of time and for producing a signal correlated to said voltage, means for deriving a metabolic demand parameter from said signal; and means for adjusting a pacing parameter in relation to said metabolic demand parameter.
Claim 27
Dependent Claim
137 words
A cardiac stimulation apparatus comprising means for pacing a patient's heart; means for measuring impedance within the patient's body, said impedance measuring means including means for applying an electric current between at least two points on said apparatus, said means for applying an electric current further having means for variably controlling a length of time during which said electric current is applied, means for periodically and automatically adjusting said length of time to minimize measuring error, and means for sensing a voltage in response to the application of said electrical current responsive to sample said voltage at the end of said length of time and for producing a signal correlated to said voltage, means for deriving a metabolic demand parameter from said signal; and means for adjusting a pacing parameter in relation to said metabolic demand parameter.
Claim 28
Dependent Claim
50 words
The cardiac stimulation apparatus according to claim 24 wherein said means for applying an electric current comprises an active capacitance and said means for dynamically adjusting said length of time comprises means for setting said length of time as a function of said active capacitance and said metabolic demand parameter.
Claim 29
Dependent Claim
48 words
The cardiac stimulation apparatus according to claim 25 wherein said means for setting said length of time comprise means for setting said length of time to a length of time substantially equal to a product of said active capacitance and a rolling average of said metabolic demand parameter.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-07-02 | 2000-01-01 | 2000-07-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-07-02 | 2004-01-01 | 2004-07-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-07-02 | 2008-01-01 | 2008-07-02 | $7700.00 | Window Closed / Lapsed |